Injectafer
Injectafer Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Injectafer is a brand name. Its generic name is Ferric Carboxymaltose.
Injectafer Introduction
Injectafer is an injectable medication used to treat iron deficiency anemia. It is used when traditional oral iron medications have been ineffective or can't be taken.Uses for Injectafer
Injectafer is used to treat iron-deficiency anemia, a condition in which the body does not have enough healthy red blood cells due to a lack of iron. It works by supplementing the body with iron so that the body can make healthy red blood cells. It is especially useful in patients who cannot take oral iron products due to poor absorption or gastrointestinal intolerance.Mechanism of Action
Injectafer works by supplementing the body with iron, which is needed to produce hemoglobin, the substance in the red blood cells that carries oxygen to other parts of the body. It works by binding iron to an amino acid chain that is easily absorbed into the bloodstream and transported to the cells that need it. This allows for maximum iron absorption in a short period of time.How Long Does It Take to Work?
Injectafer generally begins to take effect within two to four hours of administration, and full therapeutic effects can be seen within 24 to 36 hours.Absorption and Route of Elimination
Injectafer is absorbed by the intestines and enters circulation quickly. It is then eliminated via the kidneys in the urine.Dosage and Administration
Injectafer is administered as an intravenous infusion over 30 minutes. The recommended dose is a single dose of 1000 mg administered intravenously over 30 minutes.Side Effects
Common side effects of Injectafer include headache, nausea, vomiting, abdominal pain, and dizziness.Toxicity
Injectafer has a low toxicity, and no serious reactions have been reported with its use.Precaution
Injectafer should be used with caution in patients with known hypersensitivities to the product or its components.Interactions
Injectafer may interact with certain medications that you may be taking. Therefore, it is important to inform your doctor of all medications you are taking, including vitamins, minerals and herbs before starting this medication.Disease Interactions
Injectafer may interact with certain diseases, such as kidney disease, liver disease and heart disease. Therefore, it is important to inform your doctor of any diseases you have before taking this medication.Drug Interactions
Injectafer may interact with certain medications, such as traditional oral iron therapies, antacids, and anti-inflammatories. Therefore, it is important to inform your doctor of all medications you are taking before starting on this medication.Food Interactions
Injectafer should not be taken with foods that are high in vitamin C, as this may interfere with the absorption of the medication.Pregnancy Use
Injectafer should be used with caution during pregnancy, as it may affect fetal growth and development. Therefore, it is recommended to discuss the risks and benefits of taking this medication with your doctor before using it during pregnancy.Lactation Use
Injectafer is excreted in breast milk, and should be used with caution while breastfeeding.Acute Overdose
An acute overdose of Injectafer is not likely to cause serious harm. However, it is important to seek medical attention if an overdose is suspected.Contraindication
Injectafer is contraindicated in patients with known hypersensitivity to the product or any of its components. It is also contraindicated in patients with a history of iron overload, or conditions associated with iron overload, such as hemochromatosis.Use Direction
FerricCarboxymaltose should be administered as an intravenous infusion over 30 minutes. The recommended dose is 1000 mg administered intravenously over 30 minutes.Storage Conditions
Injectafer should be stored at room temperature, between 59°F and 86°F (15°C and 30°C). It should be stored away from light and moisture.Volume of Distribution
The volume of distribution of Injectafer is estimated to be 4.05 L/kg.Half Life
The half-life of Injectafer is approximately 5 hours.Clearance
The clearance of Injectafer is estimated to be 1.25 L/h/kg.Here you find in details version of Injectafer
Some Frequently Asked Questions About Injectafer
What is Injectafer?
Ferric carboxymaltose is a sterile, injectable, iron replacement product used to treat iron deficiency anemia (IDA) in adults. It is an iron complex consisting of a labile, non-esterified, low-molecular-weight fraction of ferric hydroxide with a carboxymaltose molecule. It is the only injectable iron replacement product available in the United States.
What are the uses of Injectafer?
Ferric carboxymaltose is used to treat iron deficiency anemia, which is a condition in which the body does not have enough healthy red blood cells because of an iron-deficiency. This medicine works by giving the body needed iron to create new healthy red blood cells.
Who produces Injectafer?
Ferric carboxymaltose is produced by laboratories such as Alvogen Pharma, Inc. and Baxter International Inc. in the United States.
Is a prescription needed to obtain Injectafer?
Yes, a prescription is needed to obtain Injectafer.
Is Injectafer a generic drug?
No, Injectafer is not a generic drug.
What should I tell my doctor before receiving Injectafer?
You should tell your doctor if you have a history of liver or kidney disease, any allergies, or if you are pregnant or breastfeeding.
What form does Injectafer come in?
Injectafer comes in a single-use vial or prefilled syringe and is administered as an intravenous (IV) infusion.
How often is Injectafer administered?
Injectafer is usually administered as an intravenous (IV) infusion once a month.
How long does Injectafer take to work?
Injectafer usually begins to work within a few days after receiving the first infusion. The full effect may take up to a month.
What are the possible side effects of Injectafer?
Side effects can occur with Injectafer and may include nausea, vomiting, diarrhea, dizziness, headache, skin rash, and an irregular heartbeat.
Can Injectafer be used with other medications?
You should always tell your doctor and pharmacist about all medications you are taking, including prescription, non-prescription, herbal, and nutritional supplements, before starting with Injectafer. Certain medications may interact with Injectafer and affect how it works, or increase the risk of side effects.
What should I do if I forget to take a dose of Injectafer?
If you forget to take a dose of Injectafer, contact your doctor or nurse immediately. You should not take a double dose to make up for the missed dose.
Does Injectafer require special storage conditions?
Yes, Injectafer should be stored at temperatures between 2°C to 25°C (35°F to 77°F). It should not be frozen, and should not be exposed to light.
What should I do if I experience an allergic reaction to Injectafer?
If you experience an allergic reaction to Injectafer such as skin rash, itching or hives, swelling of the face, lips, or tongue, breathing problems, or dizziness, stop using the medication and contact your doctor immediately.
How long does Injectafer stay in the body?
The half-life of Injectafer is about 3 days, but it can vary based on individual factors such as age, weight, and kidney and liver function.
What should I do if I have an overdose of Injectafer?
If you think you have taken an overdose of Injectafer, seek medical attention immediately. Symptoms of an overdose include increased heart rate, shortness of breath, and unusual fatigue or dizziness.
Can I take Injectafer if I’m pregnant or breastfeeding?
You should not take Injectafer if you are pregnant or breastfeeding unless your doctor has specifically recommended it. Discuss the potential risks and benefits with your doctor.
Is Injectafer covered by insurance?
It depends on the individual’s insurance plan. Contact your insurance provider to confirm coverage.
Is there a generic version of Injectafer available?
No, there is not a generic version of Injectafer available.
Can Injectafer be taken with food or alcohol?
Injectafer should be taken as directed by your doctor. Ask your doctor if it is safe to take with food or alcohol.
What is the recommended dosage of Injectafer?
The recommended dose of Injectafer is 15 to 1000 mg (based on body weight) administered as an intravenous (IV) infusion over at least 15 minutes, not more than once a month.
How should Injectafer be administered?
Injectafer should be administered as an IV infusion over at least 15 minutes. Your healthcare provider will determine the best dosage and infusion rate for you.
Is Injectafer safe for children?
Injectafer is not approved for use in children; however, it is possible that it could be prescribed for a child in certain circumstances. Speak with your child's doctor to determine if Injectafer is right for your child.
Can Injectafer be taken with other iron supplements?
No, Injectafer should not be taken with other iron supplements such as oral iron tablets or iron drops. Taking other iron supplements with Injectafer can lead to toxicity.
What should I do if I experience problems with the device used to administer Injectafer?
If you experience any problems with the device used to administer Injectafer, contact your healthcare provider immediately.
What is the most common side effect of Injectafer?
The most common side effect of Injectafer is nausea.
Is Injectafer considered a safe medication?
Injectafer is considered safe when used as directed. However, some people may be more sensitive to the effects of Injectafer and may experience side effects such as nausea, vomiting, headache, and skin rash.
How long does a Injectafer infusion take?
The infusion of Injectafer usually takes 15 minutes or less to complete.
What is the difference between Injectafer and other iron replacement products?
Injectafer is an injectable iron replacement product while other iron replacement products are taken orally. Injectafer is more effective in restoring hemoglobin levels in people with iron deficiency anemia than traditional oral supplements.
Can Injectafer be used to treat anemia not related to iron deficiency?
No, Injectafer is not recommended for use in people with anemia not related to iron deficiency.
Is Injectafer safe for long-term use?
Injectafer is generally safe for long-term use, but should only be used under the supervision of a healthcare professional. Speak to your doctor if you have any concerns.
What are the potential benefits of Injectafer?
Injectafer is generally used to treat iron deficiency anemia and can help to improve energy levels, restore red blood cell production, and improve muscle and organ function.
Is Injectafer available over-the-counter?
No, Injectafer is not available over-the-counter; it is a prescription only medicine.
Does Injectafer have any drug interactions?
Certain medications may interact with Injectafer and affect how it works, or increase the risk of side effects. It is important to tell your doctor and pharmacist about all medications you are taking before starting with Injectafer.
Who should not take Injectafer?
Injectafer is not recommended for people with a history of liver or kidney disease, any allergies, or those who are pregnant or breastfeeding unless specifically recommended by a doctor. Speak to your doctor if you have any concerns.
Can Injectafer interact with other medications?
Yes, certain medications can interact with Injectafer and affect how it works, or increase the risk of side effects. It is important to tell your doctor and pharmacist about all medications you are taking, including prescription, non-prescription, herbal, and nutritional supplements, before starting with Injectafer.
What are the signs of an allergic reaction to Injectafer?
Signs of an allergic reaction to Injectafer can include skin rash, itching or hives, swelling of the face, lips, or tongue, breathing problems, or dizziness. If you experience any of these signs, stop using Injectafer and contact your doctor or healthcare provider immediately.