Hi-gab

Hi-gab Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Hi-gab is a brand name. Its generic name is Gabapentin.

Introduction

Hi-gab is a white to off-white crystalline solid with a pK a1 of 3.7 and a pK a2 of 11. It's structural formula is: C9H17NO2•HCl

Uses For

Hi-gab is used to treat partial seizures, post-herpetic neuralgia, and neuropathic pain associated with diabetic peripheral neuropathy.

Mechanism of Action

Hi-gab binds to calcium channels located in the central nervous system. This action results in a reduction of the release of several neurotransmitters, including glutamate, substance P, and calcitonin gene-related peptide, which are important for controlling seizures and pain perception.

How Long Does It Take to Work?

The effects of gabapentin can begin to occur within a few hours of first taking the medication. In some cases, it may take up to two weeks for the full effects to be felt.

Absorption

Hi-gab is rapidly absorbed after oral administration, with peak plasma concentrations occurring within 1.5-2 hours.

Route of Elimination

Hi-gab is primarily eliminated via renal excretion and is eliminated in urine as unchanged drug.

Dosage

The recommended starting dosage of gabapentin is:

• For partial seizures in adults and adolescents aged 12 and older: 300mg orally three times a day for the first week; the dosage can then be increased up to a maximum of 2400mg/day.
• For post-herpetic neuralgia in adults and adolescents aged 12 and older: the starting dosage is 300mg orally, three times a day; the dosage can then be increased up to a maximum of 2400mg/day.
• For neuropathic pain associated with diabetic peripheral neuropathy in adults and adolescents aged 12 and older: the starting dosage is 300mg orally, followed by an escalation to 1800mg/day.

Administration

Hi-gab should be taken orally with or without food as prescribed by your doctor.

Side Effect

Common side effects of gabapentin include fatigue, dizziness, drowsiness, headache, nausea, blurred vision, dry mouth or changes in taste, constipation, nervousness, unsteadiness, insomnia, and weight gain.

Toxicity

Hi-gab is generally safe and well tolerated, however excessive doses may lead to acute toxicity. Symptoms of toxicity include confusion, disorientation, irregular heart rate, low blood pressure, and respiratory depression.

Precautions

Before taking gabapentin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Interaction

Hi-gab may interact with other drugs and supplements. It is important to tell your doctor or pharmacist about all drugs and supplements you are taking, as they could affect how gabapentin works. These drugs include, but are not limited to: antacids, opioids, certain antibiotics, antifungals, anticonvulsants, MAO inhibitors, narcotics, or certain calcium channel blockers.

Disease Interaction

Using gabapentin in combination with other drugs that affect central nervous system activity may increase the risk of serious side effects. These drugs include, but are not limited to: cold or allergy medicines, narcotic pain medicines, sleeping pills, muscle relaxers, and medicines for seizures, depression, or anxiety.

Drug Interaction

Drug interactions may affect how gabapentin works in your body, and could increase your risk of serious side effects. These interactions include, but are not limited to: certain antibiotics, antifungals, anticonvulsants, MAO inhibitors, narcotics, or certain calcium channel blockers. Be sure to tell your doctor or pharmacist about all drugs and supplements you are taking.

Food Interactions

Eating certain foods can increase the absorption of gabapentin, thus increasing the level of the drug in your body, which in turn can increase the risk of serious side effects. Therefore, it is important to avoid foods high in fat or cholesterol when taking this medication.

Pregnancy Use

Hi-gab should not be used during pregnancy unless the benefit outweighs the risk. If you become pregnant while taking gabapentin, it is important to talk to your doctor about the potential risks.

Lactation Use

It is not known if gabapentin is excreted into human milk. Because of this, it is recommended that if you are breastfeeding, you should not use gabapentin.

Acute Overdose

Symptoms of an acute overdose may include confusion, disorientation, irregular heart rate, low blood pressure, and respiratory depression.

Contraindication

Hi-gab is contraindicated in patients who have known hypersensitivity to the drug. It should also be avoided in patients with a history of renal insufficiency, as gabapentin is primarily eliminated via renal excretion.

Use Direction

Take gabapentin exactly as prescribed by your doctor. Do not take more or less than what is recommended. Taking too much gabapentin can cause serious side effects. If you are taking any other medications or supplements, talk to your doctor before using gabapentin.

Storage Condition

Hi-gab should be stored in a dry, cool place away from direct sunlight at room temperature. Keep it in a tightly closed container.

Volume of Distribution

The volume of distribution is 0.85-1.9 L/kg.

Half Life

The half life of gabapentin is 5-7 hours.

Clearance

The clearance of gabapentin is 210-310 ml/min.

Here you find in details version of Hi-gab

Some Frequently Asked Questions About Hi-gab

What is Hi-gab?

Hi-gab is an anti-epileptic medication, also called an anticonvulsant. It is used to treat certain types of seizures and is also used to treat nerve pain associated with various conditions, such as postherpetic neuralgia.

What is Hi-gab used for?

Hi-gab is used to control partial seizures in adults with epilepsy. It is also used to treat certain types of nerve pain and to treat restless legs syndrome.

How long does it take for Hi-gab to work?

The effects of Hi-gab may be seen within 2-3 days. As with any medication, individual response will vary.

How fast does Hi-gab work?

The effects of Hi-gab usually occur quite rapidly, but as with any medication, individual response will vary.

What are the side effects of Hi-gab?

The most common side effects of Hi-gab are drowsiness, dizziness, and headache. Other side effects may include swelling, confusion, depression, and difficulty breathing.

Can Hi-gab cause anxiety?

Yes, Hi-gab can cause anxiety. If you are experiencing anxiety after taking Hi-gab, it is important to talk to your doctor about the possibility of side effects.

Can you take Hi-gab with alcohol?

It is not recommended to take Hi-gab with alcohol. Combining Hi-gab with alcohol may increase the risk of side effects such as drowsiness. It is best to avoid drinking alcohol while taking Hi-gab.

Can you take Hi-gab with other medications?

Yes, Hi-gab can be taken with other medications. However, it is important to tell your doctor about all the medications, supplements, and vitamins you are taking to avoid possible interactions. Always check with your doctor before taking Hi-gab with other medications.

Is Hi-gab a narcotic?

No, Hi-gab is not a narcotic. It is an anti-epileptic medication, also called an anticonvulsant.

How long does Hi-gab stay in your system?

Hi-gab can stay in your system for up to 72 hours after your last dose. However, this time frame can vary depending on several factors, including your age, kidney function, and metabolism.

Is Hi-gab an opioid?

No, Hi-gab is not an opioid. It is an anti-epileptic medication, also called an anticonvulsant.

Can I take Hi-gab while pregnant?

It is not recommended to take Hi-gab while pregnant. Talk to your doctor about the risks and benefits of taking Hi-gab during pregnancy.

Can I take Hi-gab while breastfeeding?

It is not recommended to take Hi-gab while breastfeeding. Talk to your doctor about the risks and benefits of taking Hi-gab while breastfeeding.

Can Hi-gab help with nerve pain?

Yes, Hi-gab can be used to treat nerve pain. It is commonly used to treat postherpetic neuralgia, a common complication of shingles.

Does Hi-gab cause weight gain?

Yes, weight gain is a possible side effect of Hi-gab. If you are experiencing weight gain while taking Hi-gab, it is important to talk to your doctor about the possibility of adjusting the dosage.

Can you overdose on Hi-gab?

Yes, it is possible to overdose on Hi-gab. Taking too much Hi-gab can cause symptoms such as confusion, drowsiness, and slowed breathing. If you think you have overdosed on Hi-gab, it is important to seek medical attention immediately.

Is Hi-gab effective for treating seizures?

Yes, Hi-gab is effective for treating certain types of seizures. It is used to control partial seizures in adults with epilepsy.

What are the long-term effects of Hi-gab?

The long-term effects of Hi-gab are largely unknown. Common side effects may include increased fatigue, changes in behavior, and dizziness. Rare side effects may include severe allergic reactions and serotonin syndrome.

Can Hi-gab cause hair loss?

Yes, hair loss is a possible side effect of Hi-gab. If you are experiencing hair loss while taking Hi-gab, it is important to talk to your doctor about the possibility of adjusting the dosage.

Can I take ibuprofen with Hi-gab?

Yes, ibuprofen can be taken with Hi-gab. However, it is important to talk to your doctor before taking any medications together.

Does Hi-gab cause hallucinations?

Yes, hallucinations are a possible side effect of Hi-gab. If you experience hallucinations after taking Hi-gab, it is important to talk to your doctor about the possibility of adjusting the dosage.

Does Hi-gab affect blood pressure?

Yes, Hi-gab may affect blood pressure. Taking Hi-gab may increase the risk of low blood pressure, which can cause dizziness and light-headedness.

Can I take Tylenol with Hi-gab?

Yes, Tylenol can be taken with Hi-gab. However, it is important to talk to your doctor before taking any medications together.

Is Hi-gab habit forming?

No, Hi-gab is not a habit forming medication. However, if you feel like you need to take higher doses then you should talk to your doctor about the possibility of adjusting the dosage.

Does Hi-gab help with anxiety?

Yes, Hi-gab can help with anxiety. It is used to treat certain types of anxiety disorders. However, it is important to talk to your doctor before starting Hi-gab to treat anxiety.

Does Hi-gab help with sleep?

Yes, Hi-gab can help with sleep. It is used to treat certain types of sleep disorders, such as insomnia and restless legs syndrome.

Can I take Hi-gab with Xanax?

Yes, Hi-gab can be taken with Xanax. However, it is important to talk to your doctor before taking any medications together.

Can I take Hi-gab with Wellbutrin?

Yes, Hi-gab can be taken with Wellbutrin. However, it is important to talk to your doctor before taking any medications together.

Can I take Hi-gab with Prozac?

Yes, Hi-gab can be taken with Prozac. However, it is important to talk to your doctor before taking any medications together.

Can Hi-gab cause liver damage?

Yes, liver damage is a possible side effect of Hi-gab. If you experience any signs or symptoms of liver damage after taking Hi-gab, it is important to talk to your doctor about the possibility of adjusting the dosage.

Does Hi-gab help with nerve pain?

Yes, Hi-gab can help with nerve pain. It is commonly used to treat postherpetic neuralgia, a common complication of shingles.

Does Hi-gab cause constipation?

Yes, constipation is a possible side effect of Hi-gab. If you experience constipation while taking Hi-gab, it is important to talk to your doctor about the possibility of adjusting the dosage.

Can Hi-gab cause dizziness?

Yes, dizziness is a possible side effect of Hi-gab. If you experience dizziness after taking Hi-gab, it is important to talk to your doctor about the possibility of adjusting the dosage.

Is Hi-gab an anti-inflammatory?

No, Hi-gab is not an anti-inflammatory. It is an anti-epileptic medication, also called an anticonvulsant.

Can I take Hi-gab with Ativan?

Yes, Hi-gab can be taken with Ativan. However, it is important to talk to your doctor before taking any medications together.

Can I take Hi-gab with Flexeril?

Yes, Hi-gab can be taken with Flexeril. However, it is important to talk to your doctor before taking any medications together.

Can I take Hi-gab with Tramadol?

Yes, Hi-gab can be taken with Tramadol. However, it is important to talk to your doctor before taking any medications together.

Does Hi-gab help with depression?

Yes, Hi-gab can help with depression. It is used to treat certain types of depression and has been shown to be effective in reducing symptoms of depression.

Does Hi-gab help with withdrawal symptoms?

Yes, Hi-gab can help with withdrawal symptoms. It is commonly used to treat drug and alcohol withdrawal, as well as nicotine withdrawal.

Can I take Hi-gab with Ambien?

Yes, Hi-gab can be taken with Ambien. However, it is important to talk to your doctor before taking any medications together.

Can I take Hi-gab with Zoloft?

Yes, Hi-gab can be taken with Zoloft. However, it is important to talk to your doctor before taking any medications together.

What is the maximum dosage of Hi-gab?

The maximum dosage of Hi-gab is 1800 mg per day. However, it is important to talk to your doctor to determine the best dosage for you.