Gzide Xr

Gzide Xr Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Gzide Xr is a brand name. Its generic name is Gliclazide.

Introduction

Gzide Xr (also known as glyburide) is an oral anti-diabetic medication used to treat type 2 diabetes. It works by encouraging the release of insulin and lowering the blood sugar levels. It may also be used for other conditions as determined by your doctor.

Uses for

Gzide Xr is used to treat type 2 diabetes by helping to lower the blood sugar levels. It is usually prescribed after other diabetes medications have been tried without successful treatment of symptom.

Mechanism of Action

Gzide Xr works to treat type 2 diabetes by increasing the effect of insulin, which signals the body to lower the blood sugar level. It can help control glucose levels by increasing the release of insulin and reducing the amount of sugar produced by the liver.

How Long Does it Take to Work?

The duration of action of gliclazide is usually 6 to 12 hours, however it can take up to two weeks for it to reach its maximal effect.

Absorption

Gzide Xr is rapidly absorbed in the gastrointestinal tract. It is mainly absorbed in the small intestine, with some absorption in the stomach.

Route of Elimination

Gzide Xr is eliminated mainly through the kidneys. Approximately 70-90% of it is excreted unchanged in the urine.

Dosage

For adults, the recommended starting dose is 30-60mg once daily before the morning meal. The dose can be increased by 30-60mg every 1-2 weeks until the desired blood sugar levels have been achieved. It is important to take the same amount and time of dose each day.

Administration

Gzide Xr should be taken as directed by your doctor, usually once daily before a meal. It should be swallowed whole with a glass of water.

Side Effect

Gzide Xr can cause side effects such as nausea, vomiting, dizziness, headache, blurred vision, paleness, stomach pain, loss of appetite, diarrhea, lightheadedness, fatigue, and constipation.

Toxicity

Gzide Xr is considered to be a low toxicity medication. In case of overdose, symptomatic and supportive treatment should be provided.

Precautions

Gzide Xr can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.

Interaction

Gzide Xr can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.

Disease Interaction

Gzide Xr may interact with certain diseases and conditions such as liver, kidney, or heart disease; thyroid disorders; and asthma. It is important to tell your doctor about all of your medical conditions before taking gliclazide.

Drug Interactions

Gzide Xr may interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.

Food Interactions

Gzide Xr can interact with certain foods and beverages and increase the risk of side effects. It is important to avoid foods high in sugar and fat while taking gliclazide.

Pregnancy Use

Gzide Xr should not be used during pregnancy. Consult your doctor about the potential risks and benefits of taking gliclazide during pregnancy.

Lactation Use

It is unknown whether gliclazide is excreted in breast milk. It is recommended to avoid taking gliclazide while breastfeeding.

Acute Overdose

In case of an acute overdose of gliclazide, symptomatic and supportive treatment should be provided.

Contraindication

Gzide Xr should not be used in patients with diabetic ketoacidosis, type 1 diabetes, type 3 diabetes, and in those allergic to it.

Use Direction

Gzide Xr should be taken exactly as prescribed by your doctor. Do not increase or decrease the dose, or take the medication for a longer period of time than prescribed.

Storage Conditions

Gzide Xr should be stored at room temperature, away from direct sunlight, heat and moisture. It should be kept out of the reach of children and pets.

Volume of Distribution

The volume of distribution of gliclazide is approximately 20-50 L/kg.

Half life

The elimination half-life of gliclazide is 1.5-4.5 hours.

Clearance

The clearance of gliclazide in adults is 0.15-0.3 ml/min/kg.

Here you find in details version of Gzide Xr

Some Frequently Asked Questions About Gzide Xr

What is Gzide Xr?

Gzide Xr is a medication which belongs to the group of medicines called sulfonylureas. It is used to control blood glucose levels in people with type 2 diabetes.

How does Gzide Xr work?

Gzide Xr works by increasing the amount of insulin that is released by the pancreas which helps to control blood glucose levels in people with Type 2 diabetes.

What are the uses of Gzide Xr?

Gzide Xr is used to control blood glucose levels in people with Type 2 diabetes.

What are the side effects of Gzide Xr?

Gzide Xr may cause some side effects, including headache, nausea, weight gain, tiredness, and some skin rashes.

Does Gzide Xr cause hypoglycemia?

Yes, Gzide Xr can cause hypoglycemia, which is a condition where the blood glucose levels become too low. Symptoms of hypoglycemia include sweating, hunger, shakiness, dizziness, and confusion.

How should Gzide Xr be taken?

Gzide Xr should be taken orally usually once or twice a day as directed by your doctor.

How long does it take for Gzide Xr to work?

Gzide Xr usually starts to work within 1-2 hours after it is taken.

Does Gzide Xr need to be taken with food?

No, Gzide Xr does not need to be taken with food. It can be taken before, with, or after meals.

What is the recommended dose of Gzide Xr?

The recommended dose of Gzide Xr depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.

What should I do if I forget to take Gzide Xr?

If you forget to take Gzide Xr, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.

Should I avoid alcohol while taking Gzide Xr?

Yes, it is recommended to avoid alcohol while taking Gzide Xr as it can increase the risk of adverse effects such as low blood sugar.

Can Gzide Xr be taken while pregnant or breastfeeding?

Gzide Xr should not be taken while pregnant or breastfeeding. Speak to your doctor before taking any medication while pregnant or breastfeeding.

What foods should I avoid while taking Gzide Xr?

It is important to follow a healthy and balanced diet while taking Gzide Xr. Avoid foods high in sugar, fat, and cholesterol.

Is Gzide Xr available as a generic medication?

Yes, Gzide Xr is available as a generic medication.

What other medications should not be taken with Gzide Xr?

Certain medications can interact with Gzide Xr and should not be taken together. This includes ACE inhibitors, diuretics, sulfonamides, cimetidine, and other sulfonylureas.

Can I take Gzide Xr with metformin?

Yes, Gzide Xr can be taken with metformin. It is important to take both medications as prescribed by your doctor.

Are there any alternatives to Gzide Xr?

Yes, there are other medications available to control blood glucose levels. Speak to your doctor or pharmacist about other alternatives.

Can Gzide Xr be used to treat type 1 diabetes?

No, Gzide Xr is not suitable for use in people with type 1 diabetes.

Does Gzide Xr cause weight gain?

Gzide Xr can cause weight gain in some cases. It is important to follow a healthy and balanced diet and to exercise regularly.

What should I do if I experience side effects while taking Gzide Xr?

If you experience side effects while taking Gzide Xr, speak to your doctor or pharmacist. They may be able to suggest a change in dosage or medication to help alleviate the side effects.

Can diabetic ketoacidosis occur while taking Gzide Xr?

Yes, diabetic ketoacidosis can occur while taking Gzide Xr. Symptoms include dry mouth, thirst, fatigue, fruity odor on breath, and rapid breathing.

How should Gzide Xr be stored?

Gzide Xr should be stored at room temperature away from direct sunlight and heat. Do not keep Gzide Xr in the refrigerator or freezer.

Can I overdose on Gzide Xr?

Yes, it is possible to overdose on Gzide Xr. If you or someone you know has taken an overdose, call your local poison control center or emergency services immediately.

Can I donate blood while taking Gzide Xr?

No, it is recommended that you do not donate blood while taking Gzide Xr.

Can I take Gzide Xr if I have kidney disease?

It is recommended that you speak to your doctor before taking Gzide Xr if you have kidney disease. Your doctor may recommend a different medication.

Is Gzide Xr a blood thinner?

No, Gzide Xr is not a blood thinner. It is used to control blood glucose levels in people with Type 2 diabetes.

Can Gzide Xr be used to treat Type 1 diabetes?

No, Gzide Xr is not suitable for use in people with Type 1 diabetes.

Can Gzide Xr cause low blood pressure?

Yes, Gzide Xr can cause low blood pressure, which can cause dizziness, lightheadedness, and fainting.

Can I take Gzide Xr while taking other medications?

It is important to let your doctor know about all medications that you are taking before taking Gzide Xr. Certain medications can interact with Gzide Xr.

Does Gzide Xr raise cholesterol levels?

Yes, Gzide Xr can raise cholesterol levels. It is important to follow a healthy and balanced diet to help maintain healthy cholesterol levels.

Is Gzide Xr a steroid?

No, Gzide Xr is not a steroid. It is used to control blood glucose levels in people with Type 2 diabetes.

Does Gzide Xr cause diarrhea?

Yes, Gzide Xr can cause diarrhea. If you experience diarrhea while taking Gzide Xr, speak to your doctor or pharmacist.

Can I take Gzide Xr with ibuprofen?

It is recommended that you do not take Gzide Xr with ibuprofen as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.

Can I take Gzide Xr with muscle relaxers?

It is recommended that you do not take Gzide Xr with muscle relaxers as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.

What should I do if I miss a dose of Gzide Xr?

If you miss a dose of Gzide Xr, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.

Can I take Gzide Xr while breastfeeding?

No, it is recommended that you do not take Gzide Xr while breastfeeding. Speak to your doctor before taking any medications while breastfeeding.

Can I take Gzide Xr while pregnant?

No, it is recommended that you do not take Gzide Xr while pregnant. Speak to your doctor before taking any medications while pregnant.

Can Gzide Xr cause headaches?

Yes, Gzide Xr can cause headaches in some people. If you experience headaches while taking Gzide Xr, speak to your doctor or pharmacist.

Can I take Gzide Xr with other diabetes medications?

Yes, Gzide Xr can be taken with other diabetes medications. It is important to follow the instructions of your doctor or pharmacist.

What should I do if I experience low blood sugar while taking Gzide Xr?

If you experience low blood sugar while taking Gzide Xr, it is important to eat or drink something sugary, such as fruit juice, honey, candy, or a glucose tablet. It is also important to speak to your doctor or pharmacist.

Are there any foods that I should avoid while taking Gzide Xr?

It is important to follow a healthy and balanced diet while taking Gzide Xr. Avoid foods high in sugar, fat, and cholesterol.

How long can I take Gzide Xr for?

The length of time that you take Gzide Xr for depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.

Is Gzide Xr a controlled substance?

No, Gzide Xr is not a controlled substance.