Gliclaz
Gliclaz Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Gliclaz is a brand name. Its generic name is Gliclazide.
Introduction
Gliclaz (also known as glyburide) is an oral anti-diabetic medication used to treat type 2 diabetes. It works by encouraging the release of insulin and lowering the blood sugar levels. It may also be used for other conditions as determined by your doctor.Uses for
Gliclaz is used to treat type 2 diabetes by helping to lower the blood sugar levels. It is usually prescribed after other diabetes medications have been tried without successful treatment of symptom.Mechanism of Action
Gliclaz works to treat type 2 diabetes by increasing the effect of insulin, which signals the body to lower the blood sugar level. It can help control glucose levels by increasing the release of insulin and reducing the amount of sugar produced by the liver.How Long Does it Take to Work?
The duration of action of gliclazide is usually 6 to 12 hours, however it can take up to two weeks for it to reach its maximal effect.Absorption
Gliclaz is rapidly absorbed in the gastrointestinal tract. It is mainly absorbed in the small intestine, with some absorption in the stomach.Route of Elimination
Gliclaz is eliminated mainly through the kidneys. Approximately 70-90% of it is excreted unchanged in the urine.Dosage
For adults, the recommended starting dose is 30-60mg once daily before the morning meal. The dose can be increased by 30-60mg every 1-2 weeks until the desired blood sugar levels have been achieved. It is important to take the same amount and time of dose each day.Administration
Gliclaz should be taken as directed by your doctor, usually once daily before a meal. It should be swallowed whole with a glass of water.Side Effect
Gliclaz can cause side effects such as nausea, vomiting, dizziness, headache, blurred vision, paleness, stomach pain, loss of appetite, diarrhea, lightheadedness, fatigue, and constipation.Toxicity
Gliclaz is considered to be a low toxicity medication. In case of overdose, symptomatic and supportive treatment should be provided.Precautions
Gliclaz can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Interaction
Gliclaz can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Disease Interaction
Gliclaz may interact with certain diseases and conditions such as liver, kidney, or heart disease; thyroid disorders; and asthma. It is important to tell your doctor about all of your medical conditions before taking gliclazide.Drug Interactions
Gliclaz may interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Food Interactions
Gliclaz can interact with certain foods and beverages and increase the risk of side effects. It is important to avoid foods high in sugar and fat while taking gliclazide.Pregnancy Use
Gliclaz should not be used during pregnancy. Consult your doctor about the potential risks and benefits of taking gliclazide during pregnancy.Lactation Use
It is unknown whether gliclazide is excreted in breast milk. It is recommended to avoid taking gliclazide while breastfeeding.Acute Overdose
In case of an acute overdose of gliclazide, symptomatic and supportive treatment should be provided.Contraindication
Gliclaz should not be used in patients with diabetic ketoacidosis, type 1 diabetes, type 3 diabetes, and in those allergic to it.Use Direction
Gliclaz should be taken exactly as prescribed by your doctor. Do not increase or decrease the dose, or take the medication for a longer period of time than prescribed.Storage Conditions
Gliclaz should be stored at room temperature, away from direct sunlight, heat and moisture. It should be kept out of the reach of children and pets.Volume of Distribution
The volume of distribution of gliclazide is approximately 20-50 L/kg.Half life
The elimination half-life of gliclazide is 1.5-4.5 hours.Clearance
The clearance of gliclazide in adults is 0.15-0.3 ml/min/kg.Here you find in details version of Gliclaz
Some Frequently Asked Questions About Gliclaz
What is Gliclaz?
Gliclaz is a medication which belongs to the group of medicines called sulfonylureas. It is used to control blood glucose levels in people with type 2 diabetes.
How does Gliclaz work?
Gliclaz works by increasing the amount of insulin that is released by the pancreas which helps to control blood glucose levels in people with Type 2 diabetes.
What are the uses of Gliclaz?
Gliclaz is used to control blood glucose levels in people with Type 2 diabetes.
What are the side effects of Gliclaz?
Gliclaz may cause some side effects, including headache, nausea, weight gain, tiredness, and some skin rashes.
Does Gliclaz cause hypoglycemia?
Yes, Gliclaz can cause hypoglycemia, which is a condition where the blood glucose levels become too low. Symptoms of hypoglycemia include sweating, hunger, shakiness, dizziness, and confusion.
How should Gliclaz be taken?
Gliclaz should be taken orally usually once or twice a day as directed by your doctor.
How long does it take for Gliclaz to work?
Gliclaz usually starts to work within 1-2 hours after it is taken.
Does Gliclaz need to be taken with food?
No, Gliclaz does not need to be taken with food. It can be taken before, with, or after meals.
What is the recommended dose of Gliclaz?
The recommended dose of Gliclaz depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I forget to take Gliclaz?
If you forget to take Gliclaz, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Should I avoid alcohol while taking Gliclaz?
Yes, it is recommended to avoid alcohol while taking Gliclaz as it can increase the risk of adverse effects such as low blood sugar.
Can Gliclaz be taken while pregnant or breastfeeding?
Gliclaz should not be taken while pregnant or breastfeeding. Speak to your doctor before taking any medication while pregnant or breastfeeding.
What foods should I avoid while taking Gliclaz?
It is important to follow a healthy and balanced diet while taking Gliclaz. Avoid foods high in sugar, fat, and cholesterol.
Is Gliclaz available as a generic medication?
Yes, Gliclaz is available as a generic medication.
What other medications should not be taken with Gliclaz?
Certain medications can interact with Gliclaz and should not be taken together. This includes ACE inhibitors, diuretics, sulfonamides, cimetidine, and other sulfonylureas.
Can I take Gliclaz with metformin?
Yes, Gliclaz can be taken with metformin. It is important to take both medications as prescribed by your doctor.
Are there any alternatives to Gliclaz?
Yes, there are other medications available to control blood glucose levels. Speak to your doctor or pharmacist about other alternatives.
Can Gliclaz be used to treat type 1 diabetes?
No, Gliclaz is not suitable for use in people with type 1 diabetes.
Does Gliclaz cause weight gain?
Gliclaz can cause weight gain in some cases. It is important to follow a healthy and balanced diet and to exercise regularly.
What should I do if I experience side effects while taking Gliclaz?
If you experience side effects while taking Gliclaz, speak to your doctor or pharmacist. They may be able to suggest a change in dosage or medication to help alleviate the side effects.
Can diabetic ketoacidosis occur while taking Gliclaz?
Yes, diabetic ketoacidosis can occur while taking Gliclaz. Symptoms include dry mouth, thirst, fatigue, fruity odor on breath, and rapid breathing.
How should Gliclaz be stored?
Gliclaz should be stored at room temperature away from direct sunlight and heat. Do not keep Gliclaz in the refrigerator or freezer.
Can I overdose on Gliclaz?
Yes, it is possible to overdose on Gliclaz. If you or someone you know has taken an overdose, call your local poison control center or emergency services immediately.
Can I donate blood while taking Gliclaz?
No, it is recommended that you do not donate blood while taking Gliclaz.
Can I take Gliclaz if I have kidney disease?
It is recommended that you speak to your doctor before taking Gliclaz if you have kidney disease. Your doctor may recommend a different medication.
Is Gliclaz a blood thinner?
No, Gliclaz is not a blood thinner. It is used to control blood glucose levels in people with Type 2 diabetes.
Can Gliclaz be used to treat Type 1 diabetes?
No, Gliclaz is not suitable for use in people with Type 1 diabetes.
Can Gliclaz cause low blood pressure?
Yes, Gliclaz can cause low blood pressure, which can cause dizziness, lightheadedness, and fainting.
Can I take Gliclaz while taking other medications?
It is important to let your doctor know about all medications that you are taking before taking Gliclaz. Certain medications can interact with Gliclaz.
Does Gliclaz raise cholesterol levels?
Yes, Gliclaz can raise cholesterol levels. It is important to follow a healthy and balanced diet to help maintain healthy cholesterol levels.
Is Gliclaz a steroid?
No, Gliclaz is not a steroid. It is used to control blood glucose levels in people with Type 2 diabetes.
Does Gliclaz cause diarrhea?
Yes, Gliclaz can cause diarrhea. If you experience diarrhea while taking Gliclaz, speak to your doctor or pharmacist.
Can I take Gliclaz with ibuprofen?
It is recommended that you do not take Gliclaz with ibuprofen as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
Can I take Gliclaz with muscle relaxers?
It is recommended that you do not take Gliclaz with muscle relaxers as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
What should I do if I miss a dose of Gliclaz?
If you miss a dose of Gliclaz, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Can I take Gliclaz while breastfeeding?
No, it is recommended that you do not take Gliclaz while breastfeeding. Speak to your doctor before taking any medications while breastfeeding.
Can I take Gliclaz while pregnant?
No, it is recommended that you do not take Gliclaz while pregnant. Speak to your doctor before taking any medications while pregnant.
Can Gliclaz cause headaches?
Yes, Gliclaz can cause headaches in some people. If you experience headaches while taking Gliclaz, speak to your doctor or pharmacist.
Can I take Gliclaz with other diabetes medications?
Yes, Gliclaz can be taken with other diabetes medications. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I experience low blood sugar while taking Gliclaz?
If you experience low blood sugar while taking Gliclaz, it is important to eat or drink something sugary, such as fruit juice, honey, candy, or a glucose tablet. It is also important to speak to your doctor or pharmacist.
Are there any foods that I should avoid while taking Gliclaz?
It is important to follow a healthy and balanced diet while taking Gliclaz. Avoid foods high in sugar, fat, and cholesterol.
How long can I take Gliclaz for?
The length of time that you take Gliclaz for depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
Is Gliclaz a controlled substance?
No, Gliclaz is not a controlled substance.