Gliclam
Gliclam Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Gliclam is a brand name. Its generic name is Gliclazide.
Introduction
Gliclam (also known as glyburide) is an oral anti-diabetic medication used to treat type 2 diabetes. It works by encouraging the release of insulin and lowering the blood sugar levels. It may also be used for other conditions as determined by your doctor.Uses for
Gliclam is used to treat type 2 diabetes by helping to lower the blood sugar levels. It is usually prescribed after other diabetes medications have been tried without successful treatment of symptom.Mechanism of Action
Gliclam works to treat type 2 diabetes by increasing the effect of insulin, which signals the body to lower the blood sugar level. It can help control glucose levels by increasing the release of insulin and reducing the amount of sugar produced by the liver.How Long Does it Take to Work?
The duration of action of gliclazide is usually 6 to 12 hours, however it can take up to two weeks for it to reach its maximal effect.Absorption
Gliclam is rapidly absorbed in the gastrointestinal tract. It is mainly absorbed in the small intestine, with some absorption in the stomach.Route of Elimination
Gliclam is eliminated mainly through the kidneys. Approximately 70-90% of it is excreted unchanged in the urine.Dosage
For adults, the recommended starting dose is 30-60mg once daily before the morning meal. The dose can be increased by 30-60mg every 1-2 weeks until the desired blood sugar levels have been achieved. It is important to take the same amount and time of dose each day.Administration
Gliclam should be taken as directed by your doctor, usually once daily before a meal. It should be swallowed whole with a glass of water.Side Effect
Gliclam can cause side effects such as nausea, vomiting, dizziness, headache, blurred vision, paleness, stomach pain, loss of appetite, diarrhea, lightheadedness, fatigue, and constipation.Toxicity
Gliclam is considered to be a low toxicity medication. In case of overdose, symptomatic and supportive treatment should be provided.Precautions
Gliclam can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Interaction
Gliclam can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Disease Interaction
Gliclam may interact with certain diseases and conditions such as liver, kidney, or heart disease; thyroid disorders; and asthma. It is important to tell your doctor about all of your medical conditions before taking gliclazide.Drug Interactions
Gliclam may interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.Food Interactions
Gliclam can interact with certain foods and beverages and increase the risk of side effects. It is important to avoid foods high in sugar and fat while taking gliclazide.Pregnancy Use
Gliclam should not be used during pregnancy. Consult your doctor about the potential risks and benefits of taking gliclazide during pregnancy.Lactation Use
It is unknown whether gliclazide is excreted in breast milk. It is recommended to avoid taking gliclazide while breastfeeding.Acute Overdose
In case of an acute overdose of gliclazide, symptomatic and supportive treatment should be provided.Contraindication
Gliclam should not be used in patients with diabetic ketoacidosis, type 1 diabetes, type 3 diabetes, and in those allergic to it.Use Direction
Gliclam should be taken exactly as prescribed by your doctor. Do not increase or decrease the dose, or take the medication for a longer period of time than prescribed.Storage Conditions
Gliclam should be stored at room temperature, away from direct sunlight, heat and moisture. It should be kept out of the reach of children and pets.Volume of Distribution
The volume of distribution of gliclazide is approximately 20-50 L/kg.Half life
The elimination half-life of gliclazide is 1.5-4.5 hours.Clearance
The clearance of gliclazide in adults is 0.15-0.3 ml/min/kg.Here you find in details version of Gliclam
Some Frequently Asked Questions About Gliclam
What is Gliclam?
Gliclam is a medication which belongs to the group of medicines called sulfonylureas. It is used to control blood glucose levels in people with type 2 diabetes.
How does Gliclam work?
Gliclam works by increasing the amount of insulin that is released by the pancreas which helps to control blood glucose levels in people with Type 2 diabetes.
What are the uses of Gliclam?
Gliclam is used to control blood glucose levels in people with Type 2 diabetes.
What are the side effects of Gliclam?
Gliclam may cause some side effects, including headache, nausea, weight gain, tiredness, and some skin rashes.
Does Gliclam cause hypoglycemia?
Yes, Gliclam can cause hypoglycemia, which is a condition where the blood glucose levels become too low. Symptoms of hypoglycemia include sweating, hunger, shakiness, dizziness, and confusion.
How should Gliclam be taken?
Gliclam should be taken orally usually once or twice a day as directed by your doctor.
How long does it take for Gliclam to work?
Gliclam usually starts to work within 1-2 hours after it is taken.
Does Gliclam need to be taken with food?
No, Gliclam does not need to be taken with food. It can be taken before, with, or after meals.
What is the recommended dose of Gliclam?
The recommended dose of Gliclam depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I forget to take Gliclam?
If you forget to take Gliclam, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Should I avoid alcohol while taking Gliclam?
Yes, it is recommended to avoid alcohol while taking Gliclam as it can increase the risk of adverse effects such as low blood sugar.
Can Gliclam be taken while pregnant or breastfeeding?
Gliclam should not be taken while pregnant or breastfeeding. Speak to your doctor before taking any medication while pregnant or breastfeeding.
What foods should I avoid while taking Gliclam?
It is important to follow a healthy and balanced diet while taking Gliclam. Avoid foods high in sugar, fat, and cholesterol.
Is Gliclam available as a generic medication?
Yes, Gliclam is available as a generic medication.
What other medications should not be taken with Gliclam?
Certain medications can interact with Gliclam and should not be taken together. This includes ACE inhibitors, diuretics, sulfonamides, cimetidine, and other sulfonylureas.
Can I take Gliclam with metformin?
Yes, Gliclam can be taken with metformin. It is important to take both medications as prescribed by your doctor.
Are there any alternatives to Gliclam?
Yes, there are other medications available to control blood glucose levels. Speak to your doctor or pharmacist about other alternatives.
Can Gliclam be used to treat type 1 diabetes?
No, Gliclam is not suitable for use in people with type 1 diabetes.
Does Gliclam cause weight gain?
Gliclam can cause weight gain in some cases. It is important to follow a healthy and balanced diet and to exercise regularly.
What should I do if I experience side effects while taking Gliclam?
If you experience side effects while taking Gliclam, speak to your doctor or pharmacist. They may be able to suggest a change in dosage or medication to help alleviate the side effects.
Can diabetic ketoacidosis occur while taking Gliclam?
Yes, diabetic ketoacidosis can occur while taking Gliclam. Symptoms include dry mouth, thirst, fatigue, fruity odor on breath, and rapid breathing.
How should Gliclam be stored?
Gliclam should be stored at room temperature away from direct sunlight and heat. Do not keep Gliclam in the refrigerator or freezer.
Can I overdose on Gliclam?
Yes, it is possible to overdose on Gliclam. If you or someone you know has taken an overdose, call your local poison control center or emergency services immediately.
Can I donate blood while taking Gliclam?
No, it is recommended that you do not donate blood while taking Gliclam.
Can I take Gliclam if I have kidney disease?
It is recommended that you speak to your doctor before taking Gliclam if you have kidney disease. Your doctor may recommend a different medication.
Is Gliclam a blood thinner?
No, Gliclam is not a blood thinner. It is used to control blood glucose levels in people with Type 2 diabetes.
Can Gliclam be used to treat Type 1 diabetes?
No, Gliclam is not suitable for use in people with Type 1 diabetes.
Can Gliclam cause low blood pressure?
Yes, Gliclam can cause low blood pressure, which can cause dizziness, lightheadedness, and fainting.
Can I take Gliclam while taking other medications?
It is important to let your doctor know about all medications that you are taking before taking Gliclam. Certain medications can interact with Gliclam.
Does Gliclam raise cholesterol levels?
Yes, Gliclam can raise cholesterol levels. It is important to follow a healthy and balanced diet to help maintain healthy cholesterol levels.
Is Gliclam a steroid?
No, Gliclam is not a steroid. It is used to control blood glucose levels in people with Type 2 diabetes.
Does Gliclam cause diarrhea?
Yes, Gliclam can cause diarrhea. If you experience diarrhea while taking Gliclam, speak to your doctor or pharmacist.
Can I take Gliclam with ibuprofen?
It is recommended that you do not take Gliclam with ibuprofen as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
Can I take Gliclam with muscle relaxers?
It is recommended that you do not take Gliclam with muscle relaxers as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.
What should I do if I miss a dose of Gliclam?
If you miss a dose of Gliclam, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.
Can I take Gliclam while breastfeeding?
No, it is recommended that you do not take Gliclam while breastfeeding. Speak to your doctor before taking any medications while breastfeeding.
Can I take Gliclam while pregnant?
No, it is recommended that you do not take Gliclam while pregnant. Speak to your doctor before taking any medications while pregnant.
Can Gliclam cause headaches?
Yes, Gliclam can cause headaches in some people. If you experience headaches while taking Gliclam, speak to your doctor or pharmacist.
Can I take Gliclam with other diabetes medications?
Yes, Gliclam can be taken with other diabetes medications. It is important to follow the instructions of your doctor or pharmacist.
What should I do if I experience low blood sugar while taking Gliclam?
If you experience low blood sugar while taking Gliclam, it is important to eat or drink something sugary, such as fruit juice, honey, candy, or a glucose tablet. It is also important to speak to your doctor or pharmacist.
Are there any foods that I should avoid while taking Gliclam?
It is important to follow a healthy and balanced diet while taking Gliclam. Avoid foods high in sugar, fat, and cholesterol.
How long can I take Gliclam for?
The length of time that you take Gliclam for depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.
Is Gliclam a controlled substance?
No, Gliclam is not a controlled substance.