gilenya
gilenya Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? gilenya is a brand name. Its generic name is Fingolimod.
Introduction
gilenya is a medicine which is used to treat relapsing multiple sclerosis (MS) in adult adults. It belongs to the class of drugs called sphingosine 1-phosphate (S1P) receptor modulators or immunomodulators. It works by decreasing the activity of the immune system, which can reduce the number and severity of MS relapses and result in improved physical function.Uses For
gilenya is used to reduce the number and severity of relapses of multiple sclerosis (MS) in adults. It works by decreasing the activity of the immune system, resulting in improved physical function.Mechanism of Action
gilenya works by binding to S1P receptors located on immune cells such as T cells and B cells. This binding blocks the release of the cells from the lymph nodes, preventing them from entering the blood circulation and reducing the number of relapses of MS.How Long Does it Take to Work?
It usually takes several weeks for gilenya to start working. It can take several months or even years to see the full benefit of gilenya in reducing the number and severity of MS relapses.Absorption
gilenya is readily absorbed from the gastrointestinal tract. It reaches its maximum concentration in 1-2 hours after oral administration.Route of Elimination
gilenya is eliminated primarily by the liver. A small portion is eliminated in the feces and urine.Dose
The recommended dose of gilenya is 0.5mg (one capsule) taken orally once daily in the morning. It should be taken with food. If a dose is missed, it should be taken as soon as possible, unless it is almost time for the next dose. Do not take a double dose to make up for a missed dose.Administration
gilenya should be taken orally once daily in the morning with food.Side Effects
The most common side effects of gilenya are headache, diarrhea, fatigue, dizziness, nausea, abdominal pain, upper respiratory tract infection, and cough.Toxicity
gilenya is generally well-tolerated. However, it can cause serious and potentially life-threatening side effects such as liver toxicity, low levels of white blood cells, a weakened immune system, macular edema, bradycardia, and decreased cardiac contractility.Precaution
Patients should be advised to notify their healthcare provider if any of the following occur while taking gilenya: new or worsening MS symptoms, liver toxicity, low white blood cell count, signs of infection, macular edema, or bradycardia.Interaction
gilenya can interact with certain other medications such as live attenuated vaccines, stavudine, voriconazole, and telithromycin. Patients should discuss any other medications they are taking with their healthcare provider before starting gilenya.Disease Interaction
gilenya is not recommended for use in patients with certain diseases such as active hepatitis B or C or a history of a clinically significant liver disorder.Drug Interaction
gilenya can interact with certain other medications such as live attenuated vaccines, stavudine, voriconazole, and telithromycin. Patients should discuss any other medications they are taking with their healthcare provider before starting gilenya.Food Interactions
gilenya should be taken with food. It is not known if gilenya interacts with food.Pregnancy Use
gilenya is not recommended for use in pregnant women. Pregnant women should inform their healthcare provider if they become pregnant while taking gilenya.Lactation Use
It is not known if gilenya passes into breastmilk. Nursing mothers should discuss the risks and benefits of taking gilenya with their healthcare provider.Acute Overdose
In the event of an overdose, get medical help or contact a Poison Control Center immediately.Contraindication
gilenya is contraindicated in patients with active hepatitis B or C or a history of a clinically significant liver disorder.Use Direction
The recommended dose of gilenya is 0.5mg (one capsule) taken orally once daily in the morning with food.Storage Condition
gilenya should be stored at room temperature, away from light and moisture.Volume of Distribution
The volume of distribution of gilenya is approximately 3.6 L/kg.Half Life
The half life of gilenya is approximately 1-2 days.Clearance
The clearance of gilenya is approximately 17 L/h/kg.Here you find in details version of gilenya
Some Frequently Asked Questions About gilenya
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