Giane 35

Giane 35 Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Giane 35 is a brand name. Its generic name is Cyproterone Acetate + Ethinyl Estradiol.

Introduction

Giane 35 is a combination drug used as contraception. Cyproterone Acetate is a progestin used for contraception, and ethinyl estradiol is an estrogen used in combination with a progestin to replace the hormones of a woman's monthly cycle in hormonal contraception.

Uses

Giane 35 has multiple uses in contraception. It is used to prevent pregnancy, manage severe acne, reduce high levels of androgens or male hormones, and improve heavy menstrual bleeding.

Mechanism of Action

The mechanism of action of Giane 35 is through its hormone components. The cyproterone acetate component inhibits the formation of male hormones (DHEA, testosterone), thus reducing the wrinkle-causing androgen activity in the skin. It also helps reduce the levels of male hormones in the body. The ethinyl estradiol component functions as an estrogen, regulating the menstrual cycle and preventing ovulation.

How Long Does it Take to Work?

When taken as directed, Giane 35 may take up to 4 weeks to become fully effective. You may experience some symptomatic improvement in as little as 2 weeks.

Absorption

Giane 35 is an oral tablet formulation that is readily absorbed in the gastrointestinal tract. Peak plasma concentrations of cyproterone acetate and ethinyl estradiol typically occur 3 to 4 hours after administration.

Route of Elimination

Giane 35 is metabolized by the liver and eliminated through the gastrointestinal tract.

Dosage

Giane 35 is available as an oral tablet, typically in a dosage of 2mg of cyproterone acetate and 0.035mg of ethinyl estradiol. Depending on the indication, dosage may be increased or decreased.

Administration

Giane 35 is to be taken orally with or without food, usually once daily. It should be taken at the same time each day to maintain constant levels of the medication in the body.

Side Effects

Common side effects associated with Giane 35 include breast tenderness, spotting between periods, nausea, headaches, acne, and fluid retention.

Toxicity

The estimated upper limit for single-dose oral toxicity of Giane 35 is greater than 3750mg/kg. Treatment with 100mg/kg/day or more may result in toxicity symptoms.

Precaution

Patients who take Giane 35 should be monitored regularly for signs and symptoms of liver injury, thromboembolic complications, increase in blood pressure, changes in lipid metabolism, and other serious side effects.

Interaction

Giane 35 may interact with other drugs, including certain antibiotics, antifungal medications, and anticonvulsants. It may also interact with certain herbal supplements.

Disease Interaction

Patients with certain conditions, such as chronic liver disease, hyperlipidemia, a history of thromboembolic disorders, or cardiovascular disease, should not take Giane 35.

Drug Interaction

Giane 35 may interact with certain drugs, such as antibiotics and antifungal medications, and anticonvulsants. It may also interact with certain herbal supplements.

Food Interactions

Giane 35 should preferably be taken with food to optimize absorption. If taken on an empty stomach, it may interact with certain foods, such as fatty foods, which can reduce its effectiveness.

Pregnancy Use

Giane 35 is not to be used during pregnancy and should not be taken by women who are pregnant or may become pregnant.

Lactation Use

Giane 35 should not be used while breastfeeding.

Acute Overdose

Symptoms of an acute overdose of Giane 35 may include nausea, vomiting, dizziness, irregular heart rate, fainting, and abdominal pain. If an overdose is suspected, seek immediate medical attention.

Contraindication

Giane 35 is contraindicated in patients with a history of thromboembolic disorders, severe liver disease, and cardiovascular disease. It is also contraindicated in pregnant women or women planning to become pregnant.

Use Direction

Giane 35 is to be taken as directed by your doctor. It should be taken orally with or without food, usually once daily at the same time each day.

Storage Condition

Giane 35 should be stored at room temperature, away from direct sunlight and heat. Keep out of reach of children and pets.

Volume of Distribution

The volume of distribution of Giane 35 has not been determined.

Half Life

The elimination half-life of Giane 35 has not been determined.

Clearance

The clearance of Giane 35 has not been determined.

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