Gentussin
Gentussin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Gentussin is a brand name. Its generic name is Guaifenesin + dextromethorphan hydrobromide.
Introduction
Guaifenesin, also known as glyceryl guaiacolate, is an oral mucolytic agent used to reduce bronchial secretions and phlegm in the treatment of upper respiratory congestion due to colds, allergies, hay fever, and bronchitis. Dextromethorphan hydrobromide (DXM) is an antitussive (cough suppressant) drug used to relieve nonproductive and dry coughs. Gentussin is a combination of two drugs and is available in tablet, capsule, and syrup form.Uses
Gentussin is used to treat coughs and nasal congestion due to colds, allergies, hay fever, and bronchitis.Mechanism of Action
Guaifenesin is an expectorant that acts on the mucosal cells of the bronchial tract to facilitate the removal of accumulated secretions and reduce viscosity of secretions permitting easier movement. Dextromethorphan binds to the cough center in the brain to reduce the sensation of coughing.How long does it take to work?
Gentussin typically takes about 15-20 minutes to begin working. The true duration of relief may vary depending on the individual and the dose administered.Absorption
Gentussin is quickly absorbed from the gastrointestinal tract. The peak concentration of the drug is achieved 1-2 hours after oral administration.Route of Elimination
Gentussin is mainly eliminated from the body via the kidneys.Dosage
The recommended dosage for Gentussin is 2 teaspoons (10 mL) every 4-6 hours (maximum 8 teaspoons per 24 hour period). Adults and children 12 years of age and older should take 2 tablets every 4-6 hours (maximum 8 tablets per 24 hour period). The dosage for children 4-11 years of age should be 1 teaspoon (5 mL) or 1 tablet every 4-6 hours (maximum 4 teaspoons or 4 tablets per 24 hour period). Children under 4 years of age should not take this medication.Administration
Gentussin should be taken orally, either as a tablet or liquid form. Take this medication with a full glass of water.Side Effects
Common side effects of Gentussin include dizziness, headache, drowsiness, nausea, vomiting, dry mouth, and constipation.Toxicity
The serious adverse effects of Gentussin include seizures, life-threatening slowed or shallow breathing, drug dependence, and coma.Precautions
Before taking Gentussin, tell your doctor if you have a history of seizures, depression, head injury, kidney or liver disease, high blood pressure, glaucoma, breathing problems, sleep apnea, or if you are pregnant or breastfeeding.Drug Interactions
Gentussin may interact with other drugs, including prescription and over-the-counter drugs, herbal products, antidepressants, monoamine oxidase inhibitors (MAOIs), benzodiazepines, or alcohol. Tell your doctor all medications and supplements you use.Food Interactions
Gentussin may interact with certain foods or beverages. Tell your doctor if you eat or drink grapefruit or grapefruit juice before taking this medication.Pregnancy Use
Gentussin should be used during pregnancy only if clearly needed. Talk to your doctor about the potential risks and benefits of this medication.Lactation Use
This medication is not known to be safe for use during lactation. Talk to your doctor about the potential risks and benefits of this medication.Acute Overdose
An acute overdose of Gentussin is considered rare and may cause drowsiness, confusion, shallow breathing, and loss of consciousness. Seek immediate medical attention if you suspect an overdose.Contraindication
Gentussin is contraindicated in patients with known hypersensitivity to dextromethorphan or with any other hypersensitivity to the drug.Use Direction
Take Gentussin exactly as prescribed by your doctor. Do not take more than the recommended dose. It is important to take this medication with a full glass of water. Do not take this medication with grapefruit or grapefruit juice as it may increase the risk of certain side effects.Storage Conditions
Store at room temperature away from heat, light, and moisture.Volume of Distribution
Approximately 25-30% of a dose of Gentussin is distributed in the body.Half Life
The half life of Gentussin is about 4-8 hours.Clearance
Gentussin is mainly eliminated from the body via the kidneys. The total clearance of the drug is almost threefold higher than the renal clearance.Here you find in details version of Gentussin
Some Frequently Asked Questions About Gentussin
What is Gentussin?
Guaifenesin and dextromethorphan hydrobromide is a combination of two drugs that helps relieve cough, congestion, and other symptoms of illnesses associated with the common cold, such as the flu.
What is the purpose of taking Gentussin?
Gentussin is used to treat symptoms associated with the common cold, such as cough, congestion, and runny nose.
How does Gentussin work?
Guaifenesin works by thinning the mucus in the throat which helps to loosen congestion and make it easier to cough up. Dextromethorphan hydrobromide is an antitussive which helps suppress a cough. The combination of the two is useful for relieving cough and congestion.
What form does Gentussin come in?
Gentussin is available in liquid, capsule, and tablet form.
How do I take Gentussin?
Follow the instructions and dose directions on the package. Take with a full glass of water. Swallow the tablet or capsule whole. Do not chew or crush.
When should I take Gentussin?
Take Gentussin exactly as prescribed by your doctor or pharmacist. Your doctor will give you precise instructions about when to take it.
How long does Gentussin take to work?
Gentussin takes up to two hours to reach its maximum effectiveness.
Are there any side effects associated with Gentussin?
Gentussin can cause side effects such as nausea, dizziness, and headache. It can also cause drowsiness, so do not operate heavy machinery while taking this medication.
Are there any drug interactions I should know about?
Gentussin can interact with certain drugs, such as antibiotics, muscle relaxants, birth control pills, and some antidepressants. Talk to your doctor or pharmacist about drug interactions before taking this medication.
How often can I take Gentussin?
Do not take more than the recommended dose of Gentussin. Follow your doctor’s instructions or the package instructions regarding how often and how long to take the medication.
What should I do if I miss a dose of Gentussin?
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take it at the next scheduled time.
What should I do if I accidentally take too much Gentussin?
If you accidentally take too much Gentussin, call your doctor or go to the nearest emergency room right away. Drug overdose can be deadly.
Can I take Gentussin if I have kidney disease?
Gentussin should not be taken if you have kidney disease. Talk to your doctor before taking this medication.
Is Gentussin safe for pregnant women?
Gentussin is safe for pregnant women. However, as with all medications, consult your doctor before taking this medication.
Can I give Gentussin to children?
Gentussin can be given to children, but only if your doctor has prescribed it for them. The dosage may vary from adult dosage.
Are there any foods or drinks that should be avoided while taking Gentussin?
Gentussin should not be taken with fruit juices, alcohol, or caffeine-containing beverages.
What should I avoid while taking Gentussin?
Do not operate heavy machinery while taking Gentussin as it can cause drowsiness. Avoid drinking alcoholic beverages as it may increase drowsiness.
Is it safe to use Gentussin for a long period of time?
Gentussin should be used for the shortest period of time recommended by your doctor. Long-term use can cause side effects, so use caution when taking this medication.
Is Gentussin habit forming?
Gentussin is not known to be habit forming. However, as with all medications, do not take more than the recommended dose and follow your doctor’s instructions.
Is Gentussin available over-the-counter?
Gentussin is generally available over-the-counter. However, you should always consult your doctor beforehand to make sure you are taking the right medication.
Can I take Gentussin with other medications?
Gentussin may interact with certain medications. Talk to your doctor or pharmacist before taking any other medications along with Gentussin.
Are there any drugs or supplements that I should not take while taking Gentussin?
Certain drugs and supplements may interact with Gentussin. Examples include certain antibiotics, muscle relaxants, and birth control pills. Talk to your doctor before taking any other drugs or supplements while taking this medication.
Can I take Gentussin while breastfeeding?
Gentussin is not recommended for use in breastfeeding women. Talk to your doctor before taking this medication if you are pregnant or breastfeeding.
What should I do if I experience an allergic reaction to Gentussin?
If you experience a rash, hives, itching, difficulty breathing, or swelling of the face, tongue, or throat, stop taking Gentussin and seek medical attention right away.
Is it safe to take Gentussin while taking blood thinners or blood pressure medications?
Gentussin can interact with blood thinners and blood pressure medications. Talk to your doctor or pharmacist before taking this medication if you are taking these medications.
What other conditions should I tell my doctor before taking Gentussin?
Let your doctor know about any other medical conditions, including allergies, kidney disease, liver disease, or asthma, before taking Gentussin.
Can I take Gentussin for dry or productive coughs?
Yes, Gentussin can be used to help relieve dry and productive coughs.
What should I do if my symptoms persist even after taking Gentussin?
If your symptoms persist after taking Gentussin, seek medical attention. You may need to take a different medication or receive other treatment.
Are there any other drugs similar to Gentussin?
Other medications that are similar to Gentussin include guaifenesin/codeine and guaifenesin/pseudoephedrine.
Should I avoid activities such as driving while taking Gentussin?
Gentussin can cause drowsiness in some people, so it is best to avoid activities such as driving while taking this medication.
Is Gentussin safe for people with diabetes?
Yes, Gentussin is safe for people with diabetes. However, be sure to talk to your doctor to make sure you are taking the right medication.
Can Gentussin interact with herbal supplements?
Yes, Gentussin can interact with certain herbal supplements. Talk to your doctor or pharmacist about any herbal supplements you are taking before taking Gentussin.
Is Gentussin safe for people with high blood pressure?
Gentussin is generally safe for people with high blood pressure. However, it is best to talk to your doctor before taking this medication.
Are there any foods that should be avoided while taking Gentussin?
Gentussin should not be taken with alcohol or fruit juices. Avoid foods high in caffeine such as coffee, tea, and chocolate while taking this medication.
Can I take Gentussin if I have heart disease?
Gentussin can be taken if you have heart disease. However, talk to your doctor before taking this medication.
Is Gentussin safe for people with liver disease?
Gentussin should not be taken by people with liver disease without consulting your doctor. Your doctor may adjust the dose or prescribe a different medication.