Gemadol Retard

Gemadol Retard Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Gemadol Retard is a brand name. Its generic name is Tramadol Hydrochloride.

Introduction

Tramadol hydrochloride is a synthetic opioid analgesic used to manage moderate to moderately severe pain. It is typically used for both acute pain and chronic pain. It is sold under brand names such as Ultram, Rybix, and Conzip, and generic formulations.

Uses for

Tramadol is most commonly used for acute and chronic pain relief. It can be used to treat moderate to severe pain associated with:

• Arthritis
• Back pain
• Fibromyalgia
• Cancer
• Migraine Headaches
• Neuropathic Pain

Mechanism Of Action

Gemadol Retard works as a µ-opioid receptor agonist, similarly to other opioids such as heroin, morphine, or codeine. However, the mechanism of action with Tramadol is unique in that it not only affects the µ-opioid receptors but also inhibits the reuptake of serotonin and noradrenaline.

How Long Does It Take To Work

Gemadol Retard typically takes approximately 20-30 minutes to take effect. This may vary depending on the individual, however, with the average being 20-30 minutes.

Absorption

Tramadol hydrochloride is rapidly absorbed in the gastrointestinal tract. Maximum concentrations are observed 2-3 hours after administration.

Route Of Elimination

Tramadol hydrochloride is metabolized in the liver and then excreted primarily in the urine. Some of the drug is also excreted in the feces. The elimination half-life is approximately 6-7 hours.

Dosage

The dose of tramadol hydrochloride will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of tramadol hydrochloride. If your dose is different, do not change it unless your doctor tells you to do so.

• For oral dosage forms (capsules, tablets):

Adults—25 to 100 milligrams (mg) every four to six hours as needed. Your doctor may increase your dose if needed. However, the dose is usually not more than 400 mg per day. For children—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 mg per kilogram (kg) of body weight every four to six hours as needed. The dose is usually not more than 8 mg per kg per day.

Administration

Tramadol hydrochloride should be taken with food or a full glass of water to avoid stomach upset. It can be taken with or without food, but if taken with food it may take longer for the drug to take effect.

Side Effects

The most common side effects of tramadol hydrochloride include drowsiness, nausea, vomiting, constipation, headache, dizziness, dry mouth, and sweating. If these effects persist or worsen, contact your doctor or healthcare professional promptly.

Toxicity

Tramadol hydrochloride has a low risk of overdose. Overdoses of tramadol can cause serious respiratory depression, loss of consciousness, and death. Signs of overdose include severe drowsiness, pinpoint pupils, slow and shallow breathing, and loss of consciousness.

Precautions

Before taking tramadol, tell your doctor or pharmacist if you are allergic to it; or to other opioids (e.g., codeine, hydrocodone); or if you have any other allergies.

Interactions

Tramadol hydrochloride may interact with other medications so it is important to tell your doctor about all other medications you are taking, including non-prescription medications, vitamins and supplements, herbal products, and any recreational drugs. Certain substances may increase the risk for side effects with tramadol, so ask your doctor about any potential interactions.

Disease Interaction

Tramadol hydrochloride use may worsen certain conditions such as seizures, depression, or asthma. Tell your doctor if you have any of these conditions so they can adjust your tramadol dosage.

Drug Interactions

Tramadol may interact with other medications so it is important to tell your doctor about all other medications you are taking, including non-prescription medications, vitamins and supplements, herbal products, and any recreational drugs. Certain substances may increase the risk for side effects with tramadol, so ask your doctor about any potential interactions.

Food Interactions

Tramadol hydrochloride can be taken with or without food. Eating a large or fatty meal may slow the absorption of the drug and can make it less effective.

Pregnancy Use

Tramadol hydrochloride is not recommended during pregnancy as it may cause harm to both the mother and unborn baby. Talk with your doctor about the risks before taking this medication.

Lactation Use

It is not known whether tramadol passes into breastmilk. As a precaution, breastfeeding women should not take Tramadol hydrochloride.

Acute Overdose

The signs and symptoms of tramadol hydrochloride overdose can include severe drowsiness, pinpoint pupils, shallow and slow breathing, and loss of consciousness. If an overdose is suspected, seek emergency medical attention immediately.

Contraindications

Gemadol Retard is contraindicated in patients who have previously shown hypersensitivity to Tramadol or other opioid analgesics, patients with severe hepatic or renal impairment, patients with a history of alcohol or substance abuse, and pregnant women.

Use Direction

Gemadol Retard should be taken as prescribed by your doctor. Do not exceed the recommended dosage or duration of treatment without consulting your doctor. Take the medication with food or a full glass of water to avoid stomach upset.

Storage Condition

Store tramadol hydrochloride at room temperature away from light and moisture. Keep this medication in a safe place where others cannot reach it.

Volume Of Distribution

The volume of distribution for tramadol is 0.6 l/kg.

Half Life

The half-life of tramadol is approximately 6-7 hours.

Clearance

Tramadol has a clearance of approximately 4 liters/hour.

Here you find in details version of Gemadol Retard

Some Frequently Asked Questions About Gemadol Retard

What is Gemadol Retard?

Tramadol hydrochloride is an opioid analgesic, or pain reliever, used to treat severe pain. It belongs to a class of medications called serotonin and norepinephrine reuptake inhibitors (SNRIs) and is believed to be effective in reducing pain by increasing the amount of serotonin and norepinephrine in the brain.

How does Gemadol Retard work?

Tramadol hydrochloride works by increasing the amount of serotonin and norepinephrine in the brain. This produces a feeling of relaxation and a decrease in feelings of pain. It can also produce feelings of euphoria and overall well-being.

How is Gemadol Retard taken?

Tramadol hydrochloride is taken orally, usually in pill form. It is usually taken every four to six hours to control pain.

What are the side effects of Gemadol Retard?

Common side effects of tramadol hydrochloride include dizziness, upset stomach, dry mouth, drowsiness, sweating, and headaches. Other more serious side effects include shallow breathing, seizures, and hallucinations.

Is Gemadol Retard habit forming?

Yes, tramadol hydrochloride can be habit forming, and it can lead to dependence and addiction if it is not taken as prescribed. It is important to take it as directed by a physician and to never take more than the recommended dosage.

Can Gemadol Retard be taken with other medications?

Tramadol hydrochloride should not be taken with other medications, including over-the-counter medications. It can interact with other medications and cause serious side effects. It is important to check with a doctor before taking any other medications with tramadol hydrochloride.

How long does Gemadol Retard take to work?

The effects of tramadol hydrochloride can be felt shortly after taking it orally. Most people experience some relief within an hour or two after taking the medication.

What is the recommended dosage for Gemadol Retard?

The recommended dosage of tramadol hydrochloride is 50 to 100 milligrams taken orally every four to six hours as needed for pain relief. It is important to follow the instructions of your doctor when taking this medication.

What should I do if I miss a dose of Gemadol Retard?

If you miss a dose of tramadol hydrochloride, you should take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and take the next dose at the regular time.

What should I avoid while taking Gemadol Retard?

It is important to avoid drinking alcohol and using illegal drugs while taking tramadol hydrochloride. These substances can increase the risk of serious side effects. You should also avoid driving or operating machinery until you know how the medication affects you.

Are there any special precautions I should take while taking Gemadol Retard?

Yes, it is important to speak with your doctor before taking tramadol hydrochloride. Your doctor should be aware of any other medical conditions you have, any medications you are currently taking, and any allergies you may have. It is also important to tell your doctor if you are pregnant or breastfeeding.

What should I do if I experience side effects while taking Gemadol Retard?

If you experience any side effects while taking tramadol hydrochloride, contact your healthcare provider immediately. It is important to stop taking the medication and seek medical attention if the side effects are severe or become worse over time.

Can Gemadol Retard be used to treat other medical conditions?

Tramadol hydrochloride is only approved by the FDA for the treatment of moderate to severe pain. It should not be used to treat any other medical condition without the advice of your doctor.

Is Gemadol Retard safe for long term use?

Tramadol hydrochloride is generally safe for short-term use, but its safety for long-term use has not been established. It is important to use the medication as directed and to speak with your doctor if you have any questions or concerns about its use.

Are there any alternatives to Gemadol Retard?

Yes, there are other medications available to treat pain. These include non-steroidal anti-inflammatory drugs (NSAIDs), acetaminophen, and opioids. It is important to speak with your doctor before taking any medication to ensure that it is appropriate for your specific condition.

Can Gemadol Retard be taken with food?

Yes, Gemadol Retard can be taken with food. It is important to follow the directions of the doctor's instructions.

Is Gemadol Retard a controlled substance?

Yes, Gemadol Retard is a controlled substance and is a Schedule IV drug in the United States. It is important that it is taken only as recommended by a doctor and that it is not used illicitly.

Is Gemadol Retard safe for children?

Gemadol Retard is not approved for use in children under the age of 12. It should only be used in this age group with the advice of a doctor.

Can Gemadol Retard be used to treat anxiety?

No, Gemadol Retard is not approved for the treatment of anxiety. It is important to speak with your doctor about other treatment options for anxiety.

What should I do if I take too much Gemadol Retard?

If you take too much Gemadol Retard, it is important to seek medical attention right away. The symptoms of an overdose include shallow breathing, seizures, confusion, dizziness, and unconsciousness.

Can Gemadol Retard be bought over the counter?

No, Gemadol Retard is a prescription medication and can only be bought with a prescription from a doctor.

How long does Gemadol Retard stay in the body?

Gemadol Retard has an elimination half-life of about 6 hours, which means that half of the medication will be eliminated from the body in about 6 hours. It can stay in the body for up to 24 hours.

Should I take Gemadol Retard if I have liver or kidney disease?

No, Gemadol Retard should not be taken if you have liver or kidney disease. The medication could cause serious side effects and should be avoided in these conditions.

Can Gemadol Retard cause weight gain?

No, Gemadol Retard is not known to cause weight gain. However, it is important to speak with your doctor if you experience any unexpected changes in weight while taking the medication.

Is Gemadol Retard safe for dogs?

Yes, Gemadol Retard can be used to treat pain in dogs. However, it should only be used under the direction of a veterinarian.

Can Gemadol Retard be taken with other pain medications?

No, Gemadol Retard should not be taken with other medications for pain. It can interact with some medications and increase the risk of side effects.

What are the common withdrawal symptoms associated with Gemadol Retard?

The common withdrawal symptoms associated with tramadol hydrochloride are nausea, headache, anxiety, agitation, insomnia, and sweating. These symptoms can occur when the medication is stopped suddenly.

What should I do if I experience mental or behavioral changes while taking Gemadol Retard?

If you experience any mental or behavioral changes while taking Gemadol Retard, such as confusion, aggression, or hallucinations, it is important to seek medical attention immediately.

Is Gemadol Retard habit-forming?

Yes, Gemadol Retard can be habit-forming, and it can lead to dependence and addiction. It is important to take the medication only as directed and to never take more than the recommended dose.

Will Gemadol Retard make me drowsy?

Yes, Gemadol Retard can cause drowsiness. It is important to use caution when operating vehicles or machinery while taking the medication.

Does Gemadol Retard interact with other medications?

Yes, Gemadol Retard can interact with other medications and can increase the risk of side effects. It is important to tell your doctor about any other medications you are taking before starting treatment with tramadol hydrochloride.

What should I do if I experience an allergic reaction while taking Gemadol Retard?

If you experience an allergic reaction while taking Gemadol Retard, which can include a rash, swelling, difficulty breathing, or hives, it is important to seek medical attention immediately.

Can Gemadol Retard be used to treat chronic pain?

Yes, Gemadol Retard can be used to treat chronic pain. It is important to follow the instructions of your physician and never take more than the recommended dosage.

What should I do if I experience difficulty breathing while taking Gemadol Retard?

If you experience any difficulty breathing while taking Gemadol Retard, it is important to seek medical attention immediately. This can be a symptom of a serious side effect.

Can Gemadol Retard be abused?

Yes, Gemadol Retard can be abused. It should never be taken in ways not prescribed by a doctor or used illicitly.

Are there any foods or drinks I should avoid while taking Gemadol Retard?

It is important to avoid drinking alcohol and using illegal drugs while taking Gemadol Retard. These substances can increase the risk of serious side effects.

What is the recommended dose for elderly patients taking Gemadol Retard?

The recommended dose of Gemadol Retard for elderly patients is 25-50 milligrams taken orally every four to six hours as needed for pain relief. Your doctor will adjust the dose as needed based on your response.

How long does it take for Gemadol Retard to reach its peak effect?

It generally takes about an hour for Gemadol Retard to reach its peak effect.

Can Gemadol Retard cause liver damage?

Yes, Gemadol Retard can cause liver damage, especially when taken in large doses. It is important to follow the instructions of your doctor when taking this medication.

Is Gemadol Retard safe for pregnant women?

No, Gemadol Retard is not safe for pregnant women and should only be used when recommended by a doctor. It can increase the risk of serious side effects for the mother and the baby.

What should I do if I experience constipation while taking Gemadol Retard?

If you experience constipation while taking Gemadol Retard, it is important to increase your fluid and fiber intake and exercise regularly. If the constipation persists, it is important to speak with your doctor to discuss other treatment options.