Framycort
Framycort Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Framycort is a brand name. Its generic name is Hydrocortisone Acetate + Neomycin Sulphate.
Introduction
Framycort is a combined formulation of a corticosteroid and an antibiotic. It is used for the short-term treatment of certain skin disorders such as eczema (dermatitis), psoriasis, and infection caused by bacteria, fungi, and viruses.Uses
Framycort is used for the short-term treatment of certain skin disorders such as eczema (dermatitis), psoriasis, and infection caused by bacteria, fungi, and viruses.Mechanism of Action
Hydrocortisone Acetate is a corticosteroid hormone, it works by reducing inflammation and inhibiting the production of inflammatory mediators. Neomycin is a bactericidal antibiotic, it acts by inhibiting bacterial protein synthesis.How Long Does it Take to Work?
The effects of Framycort usually begin to be felt within a few days.Absorption
Hydrocortisone Acetate is rapidly absorbed after topical administration. Neomycin is well absorbed following topical administration.Route of Elimination
Hydrocortisone Acetate is metabolized by hepatic enzymes to inactive metabolites. Neomycin is metabolized by renal elimination.Dosage
Framycort is available in three strengths: 1%, 2.5%, and 10%. It is usually applied thinly to the affected area two to four times daily.Administration
Framycort is administered topically to the affected skin area.Side Effects
The most common side effects of Framycort include itching, burning, stinging, irritation, dry skin, redness, rash, and thinning of the skin.Toxicity
The toxicity of Framycort is generally low when used as directed. However, long-term use may lead to systemic toxicity.Precaution
Patients should inform their doctor if they experience any new or worsening symptoms; if they are taking any other medications; if they have any allergies; or if they are pregnant, planning to become pregnant, or breastfeeding. It is important to not apply Framycort on children younger than 12 years of age without the advice of a physician.Interactions
Framycort may interact with certain medications, supplements, or food allergies, so it is important to inform a doctor of any current medications or health conditions before taking this product.Disease Interactions
Framycort should be used with caution in patients with kidney or liver disease, some types of diabetes, cushing’s syndrome, or certain heart conditions.Drug Interactions
Framycort may interact with some medications, such as diuretics, oral and/or intravenous corticosteroids, antifungals, antivirals, calcium channel blockers, nonsteroidal anti-inflammatory drugs (NSAIDs), and some antibiotics. If combined with any of these products, it is important to inform a doctor immediately.Food Interactions
Framycort should not be taken with food or beverages high in sugar or caffeine.Pregnancy Use
Framycort should be used with caution during pregnancy; however, some studies have suggested it has no known effect on the fetus.Lactation Use
It is not known if Hydrocoritsone Acetate + Neomycin Sulphate passes into breast milk, so it should be used with caution in breastfeeding mothers.Acute Overdose
An acute overdose of Framycort is unlikely to cause serious symptoms; however, overdose may lead to rapid weight gain, electrolyte disturbances, and edema.Contraindication
Framycort should not be used in patients with a known hypersensitivity to any of the components of the product.Use Direction
Framycort should be applied thinly to the affected area two to four times daily. It should not be used for longer than 2 weeks in adults or 1 week in children.Storage Condition
Framycort should be stored at room temperature, away from direct light and moisture.Volume of Distribution
Hydrocortisone Acetate is known to have a large volume of distribution, ensuring rapid systemic availability.Half-Life
The half-life of Hydrocortisone Acetate is approximately 90 minutes. The half-life of Neomycin is approximately 1.3-2.5 hours.Clearance
Hydrocortisone Acetate is metabolized by hepatic enzymes to inactive metabolites. Neomycin is metabolized by renal elimination.Here you find in details version of Framycort