Follitec
Follitec Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Follitec is a brand name. Its generic name is Recombinant Follicle Stimulating Hormone (rFSH).
Introduction of Follitec
Follitec is a medication used to induce ovulation and fertility in adults. It is used to treat female infertility and infertility caused by polycystic ovary syndrome, and can be used in conjunction with other medications to increase the success rate of IVF (In Vitro Fertilization). It is identical to the natural follicle stimulating hormone produced by the body.Uses for Follitec
Recombinant FSH is primarily used to induce ovulation in women experiencing infertility. It is also used to help create and maintain pregnancies in certain cases of infertility caused by polycystic ovary syndrome or other conditions. In men, rFSH is used to increase sperm production in some cases of male infertility.Mechanism of Action
The exact mechanism of action of rFSH is still unclear, but it is believed to act on the ovaries to stimulate the growth of follicles, which contain eggs that are released during ovulation. It is thought that rFSH triggers the release of a chemical messenger, called cGMP, which in turn stimulates the release of hormones that cause the ovaries to produce eggs.How Long Does It Take to Work?
It typically takes about two weeks for rFSH to take effect, although this can vary depending on the individual. During this time, follicular growth and development should occur, and it is typically associated with an increase in the number of eggs released during ovulation.Absorption
rFSH is typically administered through subcutaneous injection, and is well absorbed into the bloodstream. It is usually detectable in the blood within 10 minutes of administration.Route of Elimination
rFSH is broken down and excreted in the urine, and is usually eliminated from the body within 24 hours.Dosage
The recommended dosage of rFSH varies depending on the individual’s body weight and the condition being treated. Generally, the dosage is between 75-225 IU, administered 1-2 times daily.Administration
rFSH is usually administered via subcutaneous injection, which means it is injected just beneath the skin, usually in the lower abdomen.Side Effects
The most common side effects of rFSH include nausea, bloating, headaches, and breast tenderness. Other possible side effects include hot flashes, vaginal dryness, and mild ovarian hyperstimulation syndrome, which occurs when too many eggs are released from the ovaries.Toxicity
rFSH is generally well tolerated, but overdose can cause serious side effects, such as severe ovarian hyperstimulation syndrome. Symptoms of overdose include abdominal pain, swelling, nausea, dizziness, and shortness of breath.Precautions
rFSH should be used with caution in people with certain medical conditions, such as hypertension, heart disease, diabetes, and kidney disease. It should also be used cautiously in women who are pregnant or breastfeeding.Interactions
rFSH may interact with other medications, including fertility drugs, antibiotics, and antifungal medications. It is important to inform your doctor of any other medications or supplements you are taking before using rFSH.Disease Interaction
rFSH may interact with certain diseases or conditions, such as diabetes, heart disease, and hypertension. It is important to inform your doctor of any preexisting conditions before using rFSH.Drug Interactions
rFSH may interact with certain medications, including fertility drugs, antibiotics, and antifungal medications. It is important to inform your doctor of any other medications or supplements you are taking before using rFSH.Food Interactions
rFSH may interact with certain foods or dietary supplements, such as grapefruit juice, glutamine, and melatonin. It is important to inform your doctor of any dietary changes you are making while using rFSH.Pregnancy Use
rFSH is not recommended for use during pregnancy due to the potential for serious side effects.Lactation Use
rFSH is not recommended for use during breastfeeding due to the potential for serious side effects.Acute Overdose
Symptoms of acute overdose of rFSH include severe ovarian hyperstimulation syndrome, which can cause abdominal pain, swelling, nausea, dizziness, and shortness of breath. If an overdose is suspected, seek immediate medical attention.Contraindications
rFSH should not be used in people who are pregnant or breastfeeding, people with certain medical conditions, such as heart disease, hypertension, and diabetes, and people who are taking certain medications, such as fertility drugs, antibiotics, and antifungal medications.Use Directions
rFSH should be used as directed by a physician. Inject rFSH subcutaneously, usually in the lower abdomen, one to two times daily. The recommended dosage may vary depending on the individual’s body weight and the condition being treated.Storage Conditions
rFSH should be stored at room temperature (68-77°F) and away from light and moisture.Volume of Distribution
The volume of distribution of rFSH is approximately 0.7L/kg.Half Life
The half-life of rFSH is approximately 20 minutes.Clearance
The clearance of rFSH is approximately 0.7ml/min/kg.Here you find in details version of Follitec