fludrex
fludrex Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? fludrex is a brand name. Its generic name is Paracetamol + Chlorpheniramine + Pseudoephedrine.
fludrex
fludrex is a medication commonly used to treat allergies, nasal congestion, and painful inflammation. It contains a combination of paracetamol, an anti-inflammatory drug; chlorpheniramine, an antihistamine; and pseudoephedrine, a decongestant. This medication works by blocking histamine, a type of chemical that triggers allergic reactions, reducing inflammation, and reducing the amount of mucus in the nasal passages.
Uses For
fludrex is used to treat the symptoms associated with allergies, allergic rhinitis, hay fever, and sinus congestion. It can also be used to treat inflammation and pain caused by seasonal allergies such as sneezing, itchy and watery eyes, and nasal congestion.
Mechanism of Action
fludrex works by blocking the action of histamine, a type of chemical that triggers allergic reactions. Chlorpheniramine is an antihistamine that reduces the effects of histamine in the body, while pseudoephedrine is a decongestant that reduces inflammation and frees up the nasal passages.
How Long Does it Take to Work?
fludrex may start to work within 15 minutes, but it may take up to a few hours for the full effects to be felt. It is important to take the medication as prescribed by a doctor to ensure effective treatment.
Absorption
fludrex is rapidly and completely absorbed from the gastrointestinal tract. Peak plasma concentrations are obtained between 1 and 3 hours after taking the medication.
Route of Elimination
fludrex is mainly eliminated by the kidney as unmetabolized drug and by the liver as metabolites. It is also eliminated through the feces and sweat.
Dosage
The recommended dose of Paracetamol + Chloropheniramine + Pseudoephedrine is one tablet every 4-6 hours for adults and children over 6 years of age. The maximum daily dose should not exceed 4 tablets per day (for adults) or 2 tablets per day (for children). It is important to follow the doctor's instructions regarding the correct dosage.
Administration
fludrex tablets should be taken orally with a glass of water. It should be taken at the same time each day, as prescribed by the doctor.
Side Effect
Common side effects associated with fludrex include headache, nausea, vomiting, dizziness, dry mouth, and drowsiness. Other more serious side effects include restlessness, confusion, agitation, hallucinations, and difficulty breathing.
Toxicity
High doses of fludrex may lead to toxic levels in the body. Symptoms of toxicity include sweating, weakness, confusion, yellowing of the skin and eyes (jaundice), pain in the abdomen and chest, and difficulty breathing.
Precaution
fludrex should be used with caution in people with heart disease, high blood pressure, or diabetes. It should also be used with caution in elderly people, as well as in people with a history of glaucoma, asthma, ulcers, or liver or kidney disease. It should not be used by children under 6 years of age.
Interaction
fludrex may interact with other medications, including certain antibiotics, antifungals, antidepressants, and antihistamines. It is important to inform the doctor about all medications being taken before starting the treatment.
Disease Interaction
fludrex should not be used in people with a history of glaucoma, asthma, ulcers, or liver or kidney disease. It should also be used with caution in people with heart disease, high blood pressure, or diabetes.
Drug Interactions
fludrex may interact with certain medications, including antibiotics, antifungals, antidepressants, and antihistamines. It is important to inform the doctor about all medications being taken before starting the treatment.
Food Interactions
fludrex should be taken with food or a full glass of water to reduce the risk of side effects. It should not be taken with drinks that contain alcohol, as this may increase the risk of side effects.
Pregnancy Use
fludrex is classified as a pregnancy category C drug, meaning it may not be safe for use during pregnancy. It is important to consult a doctor before taking the medication if pregnant or planning to become pregnant.
Lactation Use
It is not known whether fludrex passes into breast milk. Therefore, it is important to consult a doctor before taking the medication if breastfeeding.
Acute Overdose
An acute overdose of fludrex may lead to symptoms such as restlessness, confusion, agitation, hallucinations, difficulty breathing, and yellowing of the skin and eyes (jaundice). If an overdose is suspected, seek medical attention immediately.
Contraindication
fludrex should not be used in people with a known hypersensitivity to the medication. It should also not be used in children under 6 years of age.
Use Direction
fludrex should be taken as prescribed by the doctor. The recommended dose is one tablet every 4-6 hours, not exceeding 4 tablets per day for adults and 2 tablets per day for children. It should be taken with food or a full glass of water.
Storage Condition
fludrex tablets should be stored at room temperature in a cool, dry place. It should be kept away from direct heat and light, and out of the reach of children.
Volume of Distribution
The volume of distribution for fludrex is 3-4 L/kg. It is highly bound to plasma proteins, and is distributed into the various tissues and organs of the body.
Half Life
The half-life of fludrex is 1-2 hours. This means that it takes 1-2 hours for the amount of the drug in the body to be reduced to half its original level.
Clearance
fludrex has an elimination half-life of 1-2 hours. This means that it takes 1-2 hours for the body to clear half of the drug from the body. The drug is cleared mainly through hepatic metabolism and renal excretion.
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