Flamitrol Ophthalmic Solution 0.1%
Flamitrol Ophthalmic Solution 0.1% Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Flamitrol Ophthalmic Solution 0.1% is a brand name. Its generic name is Dexamethasone (Ophthalmic).
Introduction
Flamitrol Ophthalmic Solution 0.1% is a steroid medication used in the treatment of inflammation of the eye and related conditions. It is available as a topical ointment, as well as an injectable version. It is a potent anti-inflammatory agent, which decreases swelling and pain associated with eye infections and injuries.
Uses for
Flamitrol Ophthalmic Solution 0.1% is used to treat a wide range of eye conditions, such as conjunctivitis, uveitis, allergic conjunctivitis, and certain post-surgical inflamed conditions. It can also be used for a variety of minor eye infections and inflammations in children, teenagers, and adults.
Mechanism of Action
Dexamethasone (ophthalmic) works by decreasing inflammation in the eye, which reduces pain and swelling and promotes healing. It does this by blocking the release of inflammatory substances called leukotrienes and prostaglandins from immune system cells in the eye. This relief is why it is a common treatment for conjunctivitis and other inflammation and infection of the surface of the eye.
How Long Does It Take to Work?
The effects of Flamitrol Ophthalmic Solution 0.1% can be felt within hours of use. It may take several days of use for the full effects to be noticeable. The effects are temporary, so additional treatments may be needed to maintain the most effective relief of symptoms.
Absorption
Flamitrol Ophthalmic Solution 0.1% is rapidly and completely absorbed through the ocular tissues. It is usually absorbed in the cornea and conjunctiva within minutes of application.
Route of Elimination
Flamitrol Ophthalmic Solution 0.1% is metabolized by the liver and eliminated in the urine.
Dosage
Flamitrol Ophthalmic Solution 0.1% is available in the form of ointment and injection. The strength of the formulation varies from 0.1-0.3%. The ointment is typically used 2-5 times daily, and the injection is used 1-2 times daily. The dosage and length of treatment depends on the type of infection, the size of the affected area, and the individual's response to the drug.
Administration
Flamitrol Ophthalmic Solution 0.1% is usually applied topically as an ointment to the affected area, or it is injected subconjunctivally. Follow the instructions on the medication label for the suggested method of application.
Side Effect
The most common side effects of Flamitrol Ophthalmic Solution 0.1% are decreased vision, eye irritation, increased pressure in the eye, and a feeling of discomfort in the eye. It may also cause redness and itching in the eyelids. Rare side effects may also include eye pain, headaches, nausea, vomiting, and diarrhoea. If any of these effects occur, it is important to contact your doctor immediately.
Toxicity
Toxic overdose with Flamitrol Ophthalmic Solution 0.1% is very rare. To minimize the risk of overdose, never use it more than directed. In the case of an overdose, seek medical attention immediately.
Precaution
Flamitrol Ophthalmic Solution 0.1% should be used with caution in patients with a history of ocular disorders, diabetes, or high blood pressure. It should also be used cautiously in patients with kidney or liver impairment. Follow your doctor’s instructions for best results.
Interaction
Certain medications may interact with Flamitrol Ophthalmic Solution 0.1%. Be sure to tell your doctor about all medications you are taking, including prescription, over-the-counter, supplements, and herbal remedies.
Disease Interaction
Flamitrol Ophthalmic Solution 0.1% may interact with certain diseases, such as diabetes, kidney or liver problems, heart conditions, and eye problems. Be sure to tell your doctor about any other medical conditions you have before using this medication.
Drug Interaction
Certain medications may interact with Flamitrol Ophthalmic Solution 0.1%, including certain antibiotics, diuretics, and sterilants. Be sure to tell your doctor about any medications you are taking before beginning this medication.
Food Interaction
Some foods and beverages can interact with Flamitrol Ophthalmic Solution 0.1%. Be sure to tell your doctor if you are taking any herbal supplements, vitamins, or any other dietary supplements. Alcoholic beverages should also be avoided while taking this medication.
Pregnancy Use
Flamitrol Ophthalmic Solution 0.1% should not be used in pregnant or nursing women or infants. It is recommended to consult your doctor before using this medication if you are pregnant or nursing.
Lactation Use
Flamitrol Ophthalmic Solution 0.1% should not be used while breastfeeding. It is recommended to consult your doctor before using this medication if you are breastfeeding.
Acute Overdose
In case of an acute overdose of Flamitrol Ophthalmic Solution 0.1%, contact a doctor or poison control center immediately. Symptoms of an overdose can include severe eye pain, blurred vision, difficulty breathing, extreme drowsiness, and confusion.
Contraindication
Flamitrol Ophthalmic Solution 0.1% should not be used in patients with a known hypersensitivity to this drug. It should also be avoided in patients with glaucoma or corneal damage.
Use Direction
Flamitrol Ophthalmic Solution 0.1% should be used exactly as prescribed by your doctor. Do not use more or less than directed, or for a longer or shorter period of time than directed. Do not share this medication with others. If you are uncertain about how or when to use this medication, ask your doctor for further instruction.
Storage Condition
Flamitrol Ophthalmic Solution 0.1% should be stored at room temperature away from light and moisture. Keep this and all medications out of the reach of children.
Volume of Distribution
Flamitrol Ophthalmic Solution 0.1% is rapidly and completely absorbed through ocular tissues when applied topically, with little to no systemic absorption.
Half Life
The half-life of Flamitrol Ophthalmic Solution 0.1% is approximately 2-3 hours.
Clearance
Flamitrol Ophthalmic Solution 0.1% is eliminated primarily by cytochrome P450 enzyme-mediated metabolism in the liver. It is also renally eliminated in the urine.
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