Fenproporexum
Fenproporexum Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Fenproporexum is a brand name. Its generic name is Fenproporex.
Introduction
Fenproporexum is a stimulant amphetamine used as an appetite suppressant. It has been marketed in Spain and Brazil for the treatment of obesity and is an illegal drug in many countries.
Uses
Fenproporexum is used as an appetite suppressant to help control weight in people who are overweight or clinically obese.
Mechanism of Action
Fenproporexum works by binding to serotonin, dopamine, norepinephrine, and adrenergic receptors in the brain. It also acts on these receptors to cause a release of hormones responsible for metabolic and thermogenic processes. This helps to suppress hunger and increase energy expenditure.
How Long Does It Take To Work?
Fenproporexum may take up to several hours for it to take effect as it needs to be absorbed into the bloodstream and circulated throughout the body. In general, people may start to feel the effects of Fenproporexum after about two hours.
Absorption
Fenproporexum is efficiently absorbed in the gastrointestinal tract and rapidly reaches peak plasma concentrations after administration.
Route of Elimination
Fenproporexum is primarily excreted by the kidneys in the form of metabolites, with only a small amount being eliminated unchanged in the urine. It is also eliminated by the liver.
Dosage
The recommended daily dose for Fenproporexum is 10 mg for adults and 5 mg for children. It is suggested that the dose should be taken with food to enhance absorption and reduce gastrointestinal effects. The dose should be divided into three smaller doses if taken for more than one day. Fenproporexum should not be taken for more than two weeks without seeking medical advice.
Administration
Fenproporexum should be taken by mouth with or without food, usually three times a day or as directed by your doctor. It is important to take the medication exactly as prescribed by your healthcare provider.
Side Effect
Common side effects of Fenproporexum can include nervousness, headache, insomnia, dry mouth, nausea, vomiting, constipation, diarrhea, sweating, dizziness, irritability, or difficulty breathing. Contact your doctor immediately if you experience any of these side effects.
Toxicity
Excessive doses of Fenproporexum can cause serious harm. Symptoms of an overdose include rapid heart rate, high blood pressure, seizures, tremor, hallucinations, loss of consciousness, and coma.
Precaution
Fenproporexum is not for everyone and should be avoided by pregnant or nursing women, individuals with a history of drug abuse, and those with certain health conditions. Speak to your doctor before starting Fenproporexum to make sure it is suitable for you.
Interaction
Fenproporexum can interact with some medications, so it is important to tell your doctor about any other medications you are taking including vitamins and herbal supplements. It is also important to avoid alcohol while taking this medication as it can increase the risk of side effects.
Disease Interaction
Fenproporexum may worsen some medical conditions such as hypertension, glaucoma, and psychiatric or mental disorders. It can also increase the risk of seizures in patients with a history of seizure disorder. Let your doctor know about any existing health issues before taking Fenproporexum.
Drug Interaction
Certain medications can interact with Fenproporexum and either increase or decrease its effectiveness. These drugs include monoamine oxidase inhibitors (MAOIs), beta blockers, anticonvulsants, barbiturates, antihistamines, MAO inhibitors, cyclosporine, and some antibiotics. Make sure your doctor is aware of all the drugs you are taking.
Food Interaction
Food can reduce the absorption and effectiveness of Fenproporexum, so it is recommended to take the medication on an empty stomach for best effect. Avoid drinking grapefruit or grapefruit juice while taking this medication as it may increase the risk of side effects.
Pregnancy Use
Fenproporexum should be avoided during pregnancy as it can cause birth defects. Speak to your doctor for further advice.
Lactation Use
Fenproporexum is excreted in breast milk and should not be used in lactating women.
Acute Overdose
In case of an acute overdose of Fenproporexum, seek medical attention immediately. Symptoms of overdose include rapid heart rate, high blood pressure, tremor, hallucinations, seizures, loss of consciousness, and coma.
Contraindication
Fenproporexum is contraindicated in people with heart conditions, a history of drug abuse, severe hypertension, and some mental disorders. In addition, it should not be used in children, pregnant or breastfeeding women.
Use Direction
Fenproporexum should be taken as directed by your doctor. It is important to take the medication exactly as prescribed and not to exceed the recommended daily dose. It should also be taken with food to enhance absorption and reduce gastrointestinal effects.
Storage Condition
Store Fenproporexum at room temperature away from light and moisture. Keep the medication out of reach of children and pets.
Volume of Distribution
The volume of distribution of Fenproporexum is 17 L/kg.
Half Life
The half-life of Fenproporexum is approximately 12 hours.
Clearance
Fenproporexum is eliminated by renal and hepatic clearance, with a renal clearance of about 25 ml/min/kg.
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