Famila

Famila Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Famila is a brand name. Its generic name is Medroxyprogesterone (Acetate).

Introduction

Famila is a progestin medication which is commonly used for contraception and in the treatment of menstrual disorders such as amenorrhea. It is also used for endometrial hyperplasia, dysfunctional uterine bleeding, endometriosis, and breast, endometrial, and renal cancer.

Uses

Famila is used to treat a variety of conditions, including contraception, menstrual disorders, endometrial hyperplasia, dysfunctional uterine bleeding, endometriosis, and breast, endometrial, and renal cancer.

Mechanism of Action

Famila works by inhibiting the action of natural progesterone, which is a hormone produced in the body. By blocking progesterone, medroxyprogesterone (acetate) alters the natural menstrual cycle and can be used to treat certain menstrual disorders. By altering the action of progesterone, it can also be used to treat endometrial hyperplasia, dysfunctional uterine bleeding, endometriosis, and certain types of cancer.

How Long Does it Take to Work?

It generally takes several days before the effects of medroxyprogesterone (Acetate) can be seen. For contraception, it may take up to 7 days to become effective.

Absorption

Famila is rapidly and completely absorbed following oral administration. It is metabolized in the liver and excreted mainly through the feces.

Route of Elimination

Famila is metabolized in the liver and then eliminated mainly through the feces.

Dosage

Famila is available in various forms and strengths. The recommended dose for contraception is 5mg to 10mg once daily, on days 5-25 of the menstrual cycle. For endometrial hyperplasia, the recommended dose is 10mg taken daily for 2-4 weeks. For endometriosis and dysfunctional uterine bleeding, the recommended dose is 5mg taken twice daily for 5-10 days. The dose for treating endometrial cancer or breast cancer is 400-1000mg per day for 6-12 months.

Administration

Famila is typically administered orally, in the form of a tablet, capsule, or liquid solution.

Side Effects

Famila can cause a variety of side effects including headache, dizziness, fatigue, breast tenderness, nausea, vomiting, bloating, weight gain, fluid retention, mood swings, depression, and hair thinning.

Toxicity

Famila can be toxic if taken in high doses or in combination with certain medications.

Precautions

Famila should not be used in people who have liver or kidney disease, blood clotting disorders, or a history of stroke. It should also not be used in people who are pregnant or are breastfeeding.

Interaction

Famila can interact with other medications, including anticonvulsants, antidepressants, anabolic steroids, and antiretrovirals.

Disease Interaction

Famila can interact with certain diseases such as asthma, diabetes, epilepsy, hypertension, and heart failure.

Drug Interaction

Famila can interact with certain drugs such as salicylates, barbiturates, and antibiotics.

Food Interactions

Famila can interact with certain foods such as grapefruit, alcohol, and certain dairy products.

Pregnancy Use

Famila is not recommended for use during pregnancy, as it can cause birth defects.

Lactation Use

Famila is not recommended for use during lactation, as it can pass into breast milk.

Acute Overdose

In case of an acute overdose of medroxyprogesterone (acetate), seek immediate medical attention. Symptoms of an overdose include nausea, vomiting, abdominal pain, dizziness, and rapid heart rate.

Contraindication

Famila is contraindicated in people who have liver or kidney disease, blood clotting disorders, a history of stroke, or who are pregnant or breastfeeding.

Use Direction

Famila must be taken exactly as prescribed by a doctor. The dosage and duration of use will vary depending on the condition being treated.

Storage Condition

Famila should be stored at room temperature in a dry and dark place.

Volume of Distribution

The volume of distribution of medroxyprogesterone (acetate) is approximately 7.9 liters.

Half Life

The half life of medroxyprogesterone (acetate) is approximately 11 to 14 hours.

Clearance

The clearance of medroxyprogesterone (acetate) is approximately 15.5 liters/hr.

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