Eziride

Eziride Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Eziride is a brand name. Its generic name is Hyoscine Hydrobromide.

Eziride Introduction

Eziride is a medication prescribed to treat certain gastrointestinal (GI) disorders. It is an anticholinergic drug which works by preventing the transmission of nerve signals from the brain to the smooth muscles of the Gastrointestinal tract. It works by relaxing the smooth muscles in the walls of the intestines and reducing spasms and discomfort caused by GI disorders.

Uses For Eziride

Eziride is used to treat gastrointestinal conditions such as functional dyspepsia, unexplained abdominal pain, irritable bowel syndrome, and ureteral spasm. It is also used to reduce nausea and vomiting caused by certain surgeries or medical treatments.

Mechanism of Action

Eziride is an anticholinergic drug that works by blocking acetylcholine receptors in the nervous system. Acetylcholine is a neurotransmitter that transmits nerve signals from the brain to the muscles. By blocking the receptors, Eziride reduces the nerve signals and helps to relax the muscles.

How Long Does It Take to Work?

Eziride typically takes about 30-60 minutes to take effect and can last for up to 6 hours.

Absorption

Eziride is rapidly absorbed after oral administration, with peak plasma concentrations reached within 1-2 hours.

Route of Elimination

Eziride is metabolized in the liver and excreted in the urine and feces.

Dosage

The recommended dosage of Eziride for adults is 20-40mg every 8-10 hours, up to a maximum of 120-160mg per day. For children, the recommended dosage is 5mg every 8-10 hours up to a maximum of 35mg per day.

Administration

Eziride should be taken orally with a full glass of water. It can be taken with or without food.

Side Effect

The most common side effects of Eziride are drowsiness, dizziness, blurred vision, dry mouth, and constipation.

Toxicity

There is no known toxicity for Eziride. However, it can produce serious side effects in some individuals. Overdoses of Eziride can result in confusion, hallucinations, respiratory depression, coma, and death.

Precautions

Eziride should not be used by patients with glaucoma, myasthenia gravis, or an obstruction in the gastrointestinal or urinary tract. It should also be used with caution in elderly patients, as they may be more susceptible to side effects.

Interactions

Eziride may interact with other drugs, such as antacids, anticonvulsants, sedatives, narcotic pain relievers, muscle relaxants, and psychotropic drugs. When taking Eziride, it is important to tell your doctor about any other medications you are taking.

Disease Interaction

Eziride should not be used if you have a preexisting disease state such as glaucoma, myasthenia gravis, ulcerative colitis, or obstructive disease of the urinary or gastrointestinal tract. It should also be used with caution in patients with any renal impairment.

Drug Interactions

Eziride may interact with other drugs, such as antacids, anticonvulsants, sedatives, narcotic pain relievers, muscle relaxants, and psychotropic drugs. When taking Eziride, it is important to tell your doctor about any other medications you are taking.

Food Interactions

Eziride should not be taken with alcohol or cigarette smoke as they can increase its side effects.

Pregnancy Use

Eziride should not be used by pregnant women as it may cause harm to the fetus.

Lactation Use

Eziride is not advised in breastfeeding mothers as it may pass into breast milk and cause serious harm to the infant.

Acute Overdose

In case of an acute overdose of Eziride, seek immediate medical attention. Symptoms of overdose may include confusion, hallucinations, respiratory depression, coma, and death.

Contraindication

Eziride should not be used in patients with a known or suspected hypersensitivity to the drug or its metabolites. It is also contraindicated in patients with glaucoma, myasthenia gravis, ulcerative colitis, obstructive gastrointestinal or urinary tract disease.

Use Direction

Eziride should be taken orally with a full glass of water. It can be taken with or without food, usually every 8-10 hours. The recommended dosage for adults is 20-40mg a day up to a maximum of 120-160mg per day and for children is 5-35mg per day.

Storage Condition

Eziride should be stored at room temperature and kept away from light, moisture, and heat.

Volume of Distribution

The volume of distribution of Eziride is not known.

Half Life

The half-life of Eziride is up to 5 hours.

Clearance

The clearance of Eziride is not known.

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