Exebute
Exebute Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Exebute is a brand name. Its generic name is Butenafine.
Introduction
Exebute is an antifungal medication that is used to treat fungal infections of the skin, such as athlete's foot, jock itch, and ringworm. It is available as a topical cream or ointment, and is available in the United States by prescription only.Uses for
Exebute is used to treat fungal infections of the skin, such as athlete's foot, jock itch, and ringworm. It is not recommended for use in the eyes, mouth, or vagina.Mechanism of Action
Exebute works by inhibiting the growth of the fungi that cause the infection. It does so by blocking the enzyme squalene epoxidase, which is essential for the synthesis of ergosterol, a component of the fungal cell membrane. The disruption of the cell membrane renders the fungal cells unable to survive and proliferate.How Long Does it Take to Work?
It typically takes up to two weeks of regular use of butenafine for the infection to be cured. However, relief of symptoms may be experienced within the first few days of use.Absorption
Exebute is poorly absorbed through the skin, with less than 0.5% of the applied dose being systemically available.Route of Elimination
Exebute is mainly eliminated via the feces.Dosage
Exebute is available as a cream or ointment in concentrations of 2% or 1%. The dosage and duration of treatment depend on the type of infection being treated. For most fungal skin infections in adults, 2% butenafine cream is applied once daily to the affected area for one or two weeks. For athlete’s foot, the cream should be used for two to four weeks.Administration
Exebute is applied topically to the affected area of the skin. The cream or ointment should be applied freely and rubbed gently into the skin. It should not be applied to the eyes, mouth, or genital area.Side Effects
The most common side effects of butenafine are burning, itching, irritation, or dryness at the application site. If any of these side effects persist or worsen, contact your doctor. Rarely, butenafine may cause allergic reactions in some people. Seek immediate medical attention if you experience symptoms of a serious allergic reaction, such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat.Toxicity
Exebute is generally well tolerated when applied as directed. The oral LD50 in rats is greater than 2000mg/kg.Precaution
Exebute should not be used if you are allergic to any of its ingredients. It should also be used with caution in patients who have a history of allergies or asthma.Interaction
Exebute has no known drug or food interactions.Disease Interaction
Exebute has no known disease interaction.Drug Interaction
Exebute has no known drug interaction.Food Interaction
Exebute has no known food interaction.Pregnancy Use
Exebute has not been studied in pregnant women. Use butenafine with caution during pregnancy.Lactation Use
Exebute has not been studied in nursing mothers. Use butenafine with caution while nursing.Acute Overdose
No cases of acute overdose with butenafine have been reported.Contraindication
Exebute is contraindicated in patients who have known hypersensitivity to butenafine or any of its components.Use Direction
Exebute should be applied topically to the affected area once daily or as directed by your doctor. The cream or ointment should be applied generously and rubbed gently into the skin until it is fully absorbed. Do not apply to the eyes, mouth, or genital area.Storage Condition
Exebute should be stored at a room temperature of 20°C to 25°C (68°F to 77°F).Volume of Distribution
The volume of distribution for butenafine is not known.Half Life
The half-life of butenafine is not known.Clearance
The clearance of butenafine is not known.Here you find in details version of Exebute
Some Frequently Asked Questions About Exebute
What is Exebute?
Exebute is an antifungal medication that is used to treat fungal skin infections such as athlete's foot, ringworm, jock itch, and tinea cruris.
What are the possible side effects of Exebute?
Side effects of Exebute may include skin irritation, redness, itching, or stinging.
How does Exebute work?
Exebute works by inhibiting the growth of certain types of fungi. It does this by blocking the production of an enzyme that the fungi need for cell division and growth.
How should Exebute be used?
Exebute should be applied to the affected area twice daily, usually in the morning and evening and should be rubbed in until it is completely absorbed. It should be used for the full course of treatment as prescribed by the doctor.
Is Exebute safe for children?
Exebute is not recommended for use in children, as safety and efficacy have not been established in this population.
What should I do if I miss a dose of Exebute?
It is best to take Exebute as prescribed. If you miss a dose, take it as soon as you remember unless it is close to the time for the next dose. In that case, skip the missed dose and take the next dose when it is due.
Can Exebute be used while pregnant or breastfeeding?
It is best to consult the doctor for advice before using Exebute during pregnancy or whilst breastfeeding.
How long does it take for Exebute to work?
Exebute usually takes a few days to start working, but it may take several weeks before the infection is completely cleared up.
What is the difference between Exebute and clotrimazole?
Exebute and clotrimazole are both antifungal medications, however, butenafine is more effective than clotrimazole against certain types of skin fungus. Additionally, Exebute has fewer side effects than clotrimazole.
What should I do if my symptoms are not improving with Exebute?
If your symptoms are not improving after 2 weeks, it is important to contact your doctor for advice as you may need a different treatment.
Does Exebute interact with any drugs?
Exebute can interact with certain drugs used to treat HIV or AIDS, as well as some antibiotics, so it is important to tell your doctor about any medications you are taking before using Exebute.
Can I use Exebute on my face?
Exebute is not recommended for use on the face, as it can cause skin irritation. If you have a fungal infection on the face, please consult your doctor for treatment.
Can I use Exebute on my scalp?
Yes, Exebute can be used to treat fungal infections on the scalp. It should be applied to the affected areas twice daily, usually in the morning and evening and should be rubbed in until it is completely absorbed.
Can Exebute be used to treat fungal nail infections?
Exebute is not recommended for use to treat fungal nail infections. For fungal nail infections, it is recommended to use antifungal nail lacquers or creams that contain an ingredients such as amorolfine.
Does Exebute cause skin discoloration?
Exebute can cause skin discoloration in some patients. If you notice any discoloration, please contact your doctor immediately.
Do I need to use a sunscreen while using Exebute?
It is recommended to use a sunscreen while using Exebute, as it can make your skin more sensitive to the sun and may cause skin irritation.
Can Exebute be used with other topical medications?
It is important to consult your doctor before combining Exebute with other topical medications, as the combination may cause skin irritation or other adverse effects.
What should I do if I accidentally get Exebute in my eyes?
If you accidentally get Exebute in your eyes, it is important to rinse your eyes with plenty of cool water. If you experience any irritation or pain, consult your doctor.
Can Exebute be used to treat sunburn?
Exebute is not recommended for use to treat sunburn, as it is an antifungal medication. For sunburn, it is recommended to use a moisturizing cream or lotion.
Are there any alternatives to Exebute?
Yes, there are several antifungal medications that can be used to treat fungal skin infections. Talk with your doctor about other medications that may be more suitable for your condition.
Can Exebute be used in people with kidney disease?
Exebute is not recommended for use in people with kidney disease. If you have kidney disease, please consult your doctor for further advice.
Can I use Exebute if I am allergic to penicillin?
Yes, Exebute can be used in people who are allergic to penicillin. However, if you experience any allergic reactions after using Exebute, such as an itchy rash or difficulty breathing, please consult your doctor immediately.
What should I do if I am hypersensitive to Exebute?
If you experience any signs of an allergic reaction while using Exebute, such as an itchy rash or difficulty breathing, it is important to stop using the medication and contact your doctor immediately.
What is the recommended dosage of Exebute?
The recommended dosage of Exebute is to apply the cream to the affected area twice daily, usually in the morning and evening and rub it in until it is completely absorbed.
Does Exebute need to be refrigerated?
No, Exebute does not need to be refrigerated. It should be kept in a cool, dry place away from direct light.
Can I use Exebute on my diaper rash?
No, Exebute is not recommended for use on diaper rash. For diaper rash, it is best to use a diaper rash cream such as zinc oxide or petroleum jelly.
Can Exebute be used on open wounds?
No, Exebute should not be used on open wounds or lesions. For infected open wounds, it is best to use an antibiotic ointment such as mupirocin or bacitracin.
Can Exebute be used to treat yeast infections?
No, Exebute is not recommended for the treatment of yeast infections. For yeast infections, it is best to use antifungal medications such as miconazole or clotrimazole.
Can I use Exebute on my lips?
No, Exebute should not be used on the lips, as it can cause skin irritation. For lip infections, it is best to use an antifungal lip balm.
Can Exebute be used on genitals?
Yes, Exebute can be used on the genitals for the treatment of fungal skin infections. It should be applied directly to the affected area twice daily, usually in the morning and evening and should be rubbed in until it is completely absorbed.
Does Exebute cause drowsiness?
Exebute is not known to cause drowsiness. However, if you experience any drowsiness, dizziness, or blurred vision after using the medication, please contact your doctor.
Can I use Exebute and a topical steroid ointment together?
It is best to ask the doctor for advice before using Exebute and a topical steroid ointment together, as the combination may cause skin irritation or other adverse effects.
Can I use Exebute on my face for acne?
No, Exebute is not recommended for the treatment of acne, as it is an antifungal medication. For acne, it is best to use a topical acne medication such as benzoyl peroxide or adapalene.
Can Exebute be used with oral antifungal medications?
Yes, Exebute can be used with oral antifungal medications for the treatment of severe fungal skin infections. However, it is important to consult the doctor before taking any oral medications, especially if you are pregnant or breastfeeding.
Can I use Exebute on cracked skin?
No, Exebute is not recommended for use on cracked skin, as it can make the skin more sensitive to the medication and may cause skin irritation. For cracked skin, it is best to use a moisturizing cream or lotion.
Can Exebute be used on nipples while breastfeeding?
No, Exebute is not recommended for use on the nipples while breastfeeding, as it can be absorbed into the milk and passed to the baby. For nipple infections while breastfeeding, it is best to use a topical antifungal cream such as miconazole or clotrimazole.
Are there any safety concerns with using Exebute for a long period of time?
It is important to contact your doctor or pharmacist for advice before using Exebute for a long period of time, as prolonged use may cause skin irritation or other adverse effects.
Can Exebute be used for the treatment of athlete's foot?
Yes, Exebute is used to treat athlete's foot and other fungal skin infections such as ringworm, jock itch, and tinea cruris. It should be applied to the affected area twice daily and should be rubbed in until it is completely absorbed.
Can Exebute be used on cuts and scrapes?
No, Exebute should not be used on cuts or scrapes, as it is an antifungal medication. For cuts and scrapes, it is best to use an antibiotic ointment such as mupirocin or bacitracin.
Is Exebute an antibiotic?
No, Exebute is not an antibiotic. It is an antifungal medication used to treat fungal skin infections such as athlete's foot, ringworm, jock itch, and tinea cruris.
Can I wear makeup while using Exebute?
Yes, you can wear makeup while using Exebute. However, it is important to make sure that the makeup is non-comedogenic, as comedogenic makeup may cause the medication to not work as effectively.
Can Exebute cause skin discoloration?
Yes, Exebute can cause skin discoloration in some patients. If you notice any discoloration, please contact your doctor immediately.
Should I wear gloves while applying Exebute?
Yes, it is recommended to wear gloves while applying Exebute, as it can make your skin more sensitive to the medication and may cause skin irritation. It is also important to wash your hands after applying the medication.