E-Plan Max
E-Plan Max Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? E-Plan Max is a brand name. Its generic name is Levonorgestrel.
E-Plan Max Introduction
E-Plan Max is a synthetic progestin (hormone) used in many forms of birth control. It is also used to treat abnormal uterine bleeding, endometriosis, and as an emergency contraceptive. It has recently been approved by the FDA as an over-the-counter medication for emergency contraception in the United States. E-Plan Max is available in oral tablet, patch, and injection forms.
Uses For
E-Plan Max is most commonly used for contraception and emergency contraception. It is also used to regulate menstrual periods, to treat endometriosis, and to treat symptoms of premenstrual dysphoric disorder (PMDD).
Mechanism of Action
E-Plan Max works by preventing ovulation (the release of an egg from the ovary) and altering the cervical mucus to make it difficult for sperm to reach the uterus. It has a low efficacy rate if taken after ovulation has already occurred.
How Long Does it Take to Work?
E-Plan Max will begin to work immediately once taken. When taken as emergency contraception, it is most effective if taken within 24 hours after unprotected sex, but can be taken up to 5 days after. When used as a regular form of contraception, it is most effective when taken daily.
Absorption
E-Plan Max is absorbed rapidly and extensively when taken orally, and is completely absorbed after topical application.
Route of Elimination
E-Plan Max is primarily metabolized by the liver. It is eliminated principally in feces with lesser amounts excreted in urine. The elimination half-life varies from 11-16 hours.
Dosage
E-Plan Max is available in multiple dosage forms. The recommended dose for oral contraception is 0.75 mg taken once daily. The recommended dose for emergency contraception is a single dose of 1.5 mg taken as soon as possible within 72 hours of unprotected sex. Consult your healthcare provider for the appropriate dosage for your specific condition.
Administration
E-Plan Max is available in oral tablet, patch, and injection forms. Oral levonorgestrel should be taken with food to increase absorption.
Side Effect
Common side effects include nausea, headache, bloating, breast tenderness, and acne. Some women may experience decreased libido and depression. Rare side effects include pelvic pain, breast lumps, and vaginal bleeding.
Toxicity
E-Plan Max is generally well tolerated. However, if overdose is suspected, seek immediate medical attention or call the Poison Help Line at 1-800-222-1222.
Precaution
E-Plan Max may decrease the effectiveness of some medications, including barbiturates, rifampin, phenytoin, and some anticonvulsants. It may also increase the blood levels of certain anti-seizure medications. Women should not take levonorgestrel during pregnancy.
Interaction
E-Plan Max may interact with other medications, including certain antibiotics and anticonvulsants. It is important to tell your healthcare provider about all other medications you are taking before taking levonorgestrel.
Disease Interaction
E-Plan Max may exacerbate pre-existing conditions, including migraines, gallbladder disease, and depression. It is important to tell your healthcare provider about all of your medical conditions before taking levonorgestrel.
Drug Inetraction
E-Plan Max may interact with certain drugs, including certain antibiotics and anticonvulsants. It is important to tell your healthcare provider about all other medications you are taking before taking levonorgestrel.
Food Interactions
E-Plan Max is recommended to be taken with food to increase absorption. Taking it with grapefruit juice may increase the levels of levonorgestrel in the body.
Pregnancy Use
E-Plan Max is not recommended for pregnant women. It is a pregnancy category B drug, which means that it has been studied in animals and no adverse effects were seen. However, it is important to tell your healthcare provider if you become pregnant while taking levonorgestrel.
Lactation Use
E-Plan Max is excreted in breastmilk. Nursing mothers are advised to use alternate forms of contraception while taking levonorgestrel.
Acute Overdose
In the case of an acute overdose, seek medical help immediately. Symptoms of overdose may include severe nausea and vomiting.
Contraindication
E-Plan Max is contraindicated in women who have a history of acute porphyria, a condition involving abnormal production of haem, and in women who are taking certain drugs, such as cyclosporine.
Directions for Use
E-Plan Max should be taken as directed by your healthcare provider. Follow the instructions on the product label carefully. Consult your healthcare provider for any questions or concerns.
Storage Conditions
E-Plan Max should be stored at room temperature away from light and moisture. Do not store it in the bathroom.
Volume of Distribution
E-Plan Max has a volume of distribution of about 10 L/kg.
Half Life
E-Plan Max has a half-life of approximately 11-16 hours.
Clearance
E-Plan Max is cleared primarily by hepatic metabolism, with about 80% eliminated in the feces and about 20% in the urine.
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