Diasafe

Diasafe Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Diasafe is a brand name. Its generic name is Gliclazide.

Introduction

Diasafe (also known as glyburide) is an oral anti-diabetic medication used to treat type 2 diabetes. It works by encouraging the release of insulin and lowering the blood sugar levels. It may also be used for other conditions as determined by your doctor.

Uses for

Diasafe is used to treat type 2 diabetes by helping to lower the blood sugar levels. It is usually prescribed after other diabetes medications have been tried without successful treatment of symptom.

Mechanism of Action

Diasafe works to treat type 2 diabetes by increasing the effect of insulin, which signals the body to lower the blood sugar level. It can help control glucose levels by increasing the release of insulin and reducing the amount of sugar produced by the liver.

How Long Does it Take to Work?

The duration of action of gliclazide is usually 6 to 12 hours, however it can take up to two weeks for it to reach its maximal effect.

Absorption

Diasafe is rapidly absorbed in the gastrointestinal tract. It is mainly absorbed in the small intestine, with some absorption in the stomach.

Route of Elimination

Diasafe is eliminated mainly through the kidneys. Approximately 70-90% of it is excreted unchanged in the urine.

Dosage

For adults, the recommended starting dose is 30-60mg once daily before the morning meal. The dose can be increased by 30-60mg every 1-2 weeks until the desired blood sugar levels have been achieved. It is important to take the same amount and time of dose each day.

Administration

Diasafe should be taken as directed by your doctor, usually once daily before a meal. It should be swallowed whole with a glass of water.

Side Effect

Diasafe can cause side effects such as nausea, vomiting, dizziness, headache, blurred vision, paleness, stomach pain, loss of appetite, diarrhea, lightheadedness, fatigue, and constipation.

Toxicity

Diasafe is considered to be a low toxicity medication. In case of overdose, symptomatic and supportive treatment should be provided.

Precautions

Diasafe can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.

Interaction

Diasafe can interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.

Disease Interaction

Diasafe may interact with certain diseases and conditions such as liver, kidney, or heart disease; thyroid disorders; and asthma. It is important to tell your doctor about all of your medical conditions before taking gliclazide.

Drug Interactions

Diasafe may interact with other medications and increase the risk of side effects. It is important to tell your doctor about all the medications that you are taking before taking gliclazide.

Food Interactions

Diasafe can interact with certain foods and beverages and increase the risk of side effects. It is important to avoid foods high in sugar and fat while taking gliclazide.

Pregnancy Use

Diasafe should not be used during pregnancy. Consult your doctor about the potential risks and benefits of taking gliclazide during pregnancy.

Lactation Use

It is unknown whether gliclazide is excreted in breast milk. It is recommended to avoid taking gliclazide while breastfeeding.

Acute Overdose

In case of an acute overdose of gliclazide, symptomatic and supportive treatment should be provided.

Contraindication

Diasafe should not be used in patients with diabetic ketoacidosis, type 1 diabetes, type 3 diabetes, and in those allergic to it.

Use Direction

Diasafe should be taken exactly as prescribed by your doctor. Do not increase or decrease the dose, or take the medication for a longer period of time than prescribed.

Storage Conditions

Diasafe should be stored at room temperature, away from direct sunlight, heat and moisture. It should be kept out of the reach of children and pets.

Volume of Distribution

The volume of distribution of gliclazide is approximately 20-50 L/kg.

Half life

The elimination half-life of gliclazide is 1.5-4.5 hours.

Clearance

The clearance of gliclazide in adults is 0.15-0.3 ml/min/kg.

Here you find in details version of Diasafe

Some Frequently Asked Questions About Diasafe

What is Diasafe?

Diasafe is a medication which belongs to the group of medicines called sulfonylureas. It is used to control blood glucose levels in people with type 2 diabetes.

How does Diasafe work?

Diasafe works by increasing the amount of insulin that is released by the pancreas which helps to control blood glucose levels in people with Type 2 diabetes.

What are the uses of Diasafe?

Diasafe is used to control blood glucose levels in people with Type 2 diabetes.

What are the side effects of Diasafe?

Diasafe may cause some side effects, including headache, nausea, weight gain, tiredness, and some skin rashes.

Does Diasafe cause hypoglycemia?

Yes, Diasafe can cause hypoglycemia, which is a condition where the blood glucose levels become too low. Symptoms of hypoglycemia include sweating, hunger, shakiness, dizziness, and confusion.

How should Diasafe be taken?

Diasafe should be taken orally usually once or twice a day as directed by your doctor.

How long does it take for Diasafe to work?

Diasafe usually starts to work within 1-2 hours after it is taken.

Does Diasafe need to be taken with food?

No, Diasafe does not need to be taken with food. It can be taken before, with, or after meals.

What is the recommended dose of Diasafe?

The recommended dose of Diasafe depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.

What should I do if I forget to take Diasafe?

If you forget to take Diasafe, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.

Should I avoid alcohol while taking Diasafe?

Yes, it is recommended to avoid alcohol while taking Diasafe as it can increase the risk of adverse effects such as low blood sugar.

Can Diasafe be taken while pregnant or breastfeeding?

Diasafe should not be taken while pregnant or breastfeeding. Speak to your doctor before taking any medication while pregnant or breastfeeding.

What foods should I avoid while taking Diasafe?

It is important to follow a healthy and balanced diet while taking Diasafe. Avoid foods high in sugar, fat, and cholesterol.

Is Diasafe available as a generic medication?

Yes, Diasafe is available as a generic medication.

What other medications should not be taken with Diasafe?

Certain medications can interact with Diasafe and should not be taken together. This includes ACE inhibitors, diuretics, sulfonamides, cimetidine, and other sulfonylureas.

Can I take Diasafe with metformin?

Yes, Diasafe can be taken with metformin. It is important to take both medications as prescribed by your doctor.

Are there any alternatives to Diasafe?

Yes, there are other medications available to control blood glucose levels. Speak to your doctor or pharmacist about other alternatives.

Can Diasafe be used to treat type 1 diabetes?

No, Diasafe is not suitable for use in people with type 1 diabetes.

Does Diasafe cause weight gain?

Diasafe can cause weight gain in some cases. It is important to follow a healthy and balanced diet and to exercise regularly.

What should I do if I experience side effects while taking Diasafe?

If you experience side effects while taking Diasafe, speak to your doctor or pharmacist. They may be able to suggest a change in dosage or medication to help alleviate the side effects.

Can diabetic ketoacidosis occur while taking Diasafe?

Yes, diabetic ketoacidosis can occur while taking Diasafe. Symptoms include dry mouth, thirst, fatigue, fruity odor on breath, and rapid breathing.

How should Diasafe be stored?

Diasafe should be stored at room temperature away from direct sunlight and heat. Do not keep Diasafe in the refrigerator or freezer.

Can I overdose on Diasafe?

Yes, it is possible to overdose on Diasafe. If you or someone you know has taken an overdose, call your local poison control center or emergency services immediately.

Can I donate blood while taking Diasafe?

No, it is recommended that you do not donate blood while taking Diasafe.

Can I take Diasafe if I have kidney disease?

It is recommended that you speak to your doctor before taking Diasafe if you have kidney disease. Your doctor may recommend a different medication.

Is Diasafe a blood thinner?

No, Diasafe is not a blood thinner. It is used to control blood glucose levels in people with Type 2 diabetes.

Can Diasafe be used to treat Type 1 diabetes?

No, Diasafe is not suitable for use in people with Type 1 diabetes.

Can Diasafe cause low blood pressure?

Yes, Diasafe can cause low blood pressure, which can cause dizziness, lightheadedness, and fainting.

Can I take Diasafe while taking other medications?

It is important to let your doctor know about all medications that you are taking before taking Diasafe. Certain medications can interact with Diasafe.

Does Diasafe raise cholesterol levels?

Yes, Diasafe can raise cholesterol levels. It is important to follow a healthy and balanced diet to help maintain healthy cholesterol levels.

Is Diasafe a steroid?

No, Diasafe is not a steroid. It is used to control blood glucose levels in people with Type 2 diabetes.

Does Diasafe cause diarrhea?

Yes, Diasafe can cause diarrhea. If you experience diarrhea while taking Diasafe, speak to your doctor or pharmacist.

Can I take Diasafe with ibuprofen?

It is recommended that you do not take Diasafe with ibuprofen as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.

Can I take Diasafe with muscle relaxers?

It is recommended that you do not take Diasafe with muscle relaxers as it may increase the risk of adverse effects. Speak to your doctor before taking any medications together.

What should I do if I miss a dose of Diasafe?

If you miss a dose of Diasafe, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose. Do not double your dose.

Can I take Diasafe while breastfeeding?

No, it is recommended that you do not take Diasafe while breastfeeding. Speak to your doctor before taking any medications while breastfeeding.

Can I take Diasafe while pregnant?

No, it is recommended that you do not take Diasafe while pregnant. Speak to your doctor before taking any medications while pregnant.

Can Diasafe cause headaches?

Yes, Diasafe can cause headaches in some people. If you experience headaches while taking Diasafe, speak to your doctor or pharmacist.

Can I take Diasafe with other diabetes medications?

Yes, Diasafe can be taken with other diabetes medications. It is important to follow the instructions of your doctor or pharmacist.

What should I do if I experience low blood sugar while taking Diasafe?

If you experience low blood sugar while taking Diasafe, it is important to eat or drink something sugary, such as fruit juice, honey, candy, or a glucose tablet. It is also important to speak to your doctor or pharmacist.

Are there any foods that I should avoid while taking Diasafe?

It is important to follow a healthy and balanced diet while taking Diasafe. Avoid foods high in sugar, fat, and cholesterol.

How long can I take Diasafe for?

The length of time that you take Diasafe for depends on the individual and the type of diabetes. It is important to follow the instructions of your doctor or pharmacist.

Is Diasafe a controlled substance?

No, Diasafe is not a controlled substance.