Dextroamphetamine
Dextroamphetamine Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Dextroamphetamine is a brand name. Its generic name is Dextroamphetamine.
Dextroamphetamine Introduction
Dextroamphetamine is a prescription stimulant medication that is used to treat Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy. It is a form of amphetamine. Dextroamphetamine increases the levels of certain chemicals in the brain that can improve the ability to focus and stay alert.
Uses For
Dextroamphetamine is used to treat Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy in both children and adults. It is also used to improve alertness and wakefulness in people suffering from sleep disorder.
Mechanism Of Action
Dextroamphetamine works by increasing the release of neurotransmitters like dopamine and norepinephrine. These compounds are important for maintaining focus and alertness. It also inhibits the reuptake of dopamine and norepinephrine which helps keep levels of these compounds higher in the brain.
How Long Does It Take To Work?
Dextroamphetamine typically takes about 30 to 60 minutes to start working. It may take longer depending on the individual’s metabolism and other factors.
Absorption
Dextroamphetamine is quickly absorbed from the gastrointestinal tract. Peak levels of the drug can be seen after about 2 to 4 hours.
Route Of Elimination
Dextroamphetamine is primarily eliminated through the urine. It is metabolized by the liver and excreted by the kidneys.
Dosage
The dosage of dextroamphetamine depends on the individual’s weight, age, and other factors. For adults with Attention Deficit Hyperactivity Disorder (ADHD), the usual starting dosage is 5 mg once or twice daily. The dosage can be increased by increments of 5 mg. Maximum daily dosage should not exceed 40 mg per day. For children with Attention Deficit Hyperactivity Disorder, the dosage should start at 5 mg once or twice daily and can be increased by increments of 2.5 mg. Maximum daily dosage should not exceed 40 mg per day.
Administration
Dextroamphetamine should be taken orally with or without food. Capsules should not be crushed and should be swallowed whole. The tablets should be taken with a full glass of water.
Side Effect
Some of the common side effects of dextroamphetamine include headaches, loss of appetite, nausea, vomiting, stomach pain, dizziness, difficulty sleeping and dry mouth. More serious side effects include chest pain, sweating, rapid heartbeat, and agitation. It is important to consult your doctor if any of these effects persist or become worse.
Toxicity
Dextroamphetamine toxicity can be dangerous and can lead to serious consequences. Symptoms of toxicity include agitation, hyperthermia, tremors, severe headache, hallucinations, and abnormal heart rhythm. It is important to seek medical attention if any of these symptoms occur.
Precautions
Patients should be carefully monitored while taking dextroamphetamine. It should not be taken with alcohol or other drugs as this can cause adverse reactions. Patients who are pregnant, breastfeeding, or planning to become pregnant should consult a doctor before using this medication. Patients with a history of heart problems, high blood pressure, glaucoma, or any mental health disorders should also discuss usage with a doctor before starting dextroamphetamine.
Interactions
Dextroamphetamine can interact with certain medications, such as monoamine oxidase inhibitors (MAOIs), antacids, tricyclic antidepressants, and certain antibiotics. It can also interact with some herbal supplements. It is important to tell your doctor about all medications and supplements you are taking before starting dextroamphetamine.
Disease Interactions
Dextroamphetamine can interact with certain diseases, including glaucoma, seizures, and hyperthyroidism. It can also cause interactions with mental health disorders, such as bipolar disorder and anxiety. It is important to tell your doctor about your medical history before starting dextroamphetamine.
Drug Interactions
Dextroamphetamine can interact with certain other drugs, such as cold medicines, allergy medicines, and MAOIs. It can also interact with certain antidepressants and anti-seizure medications. It is important to tell your doctor about all medications you are taking before starting dextroamphetamine.
Food Interactions
Dextroamphetamine can interact with certain foods, including grapefruit, alcohol, and caffeine. It is important to ask your doctor or pharmacist about any food interactions that may occur.
Pregnancy Use
Dextroamphetamine should only be used during pregnancy if it is absolutely necessary and only after consulting a doctor. It is not recommended during breastfeeding as it can be passed to the baby.
Lactation Use
Dextroamphetamine should not be used during breastfeeding as it can be passed to the baby. It is important to ask your doctor before taking any medication while breastfeeding.
Acute Overdose
An overdose of dextroamphetamine can be dangerous and lead to serious consequences. Symptoms of an overdose include severe headache, nausea, vomiting, rapid heartbeat, agitation, seizures, coma, and death. It is important to seek immediate medical attention in case of an overdose.
Contraindications
Dextroamphetamine should not be used in patients who have a known hypersensitivity or intolerance to the drug, in patients who have a history of substance abuse, in patients who have glaucoma, in patients with heart problems, or in patients who have a history of mental health disorder.
Usage Directions
Dextroamphetamine should be taken exactly as prescribed by your doctor. Follow the detailed directions on the patient information leaflet carefully and never take more than the prescribed amount.
Storage Conditions
Dextroamphetamine should be stored in a cool, dry place and kept away from direct light and moisture. It should also be kept out of reach of pets and children.
Volume Of Distribution
Dextroamphetamine has a volume of distribution of about 2 L/kg.
Half Life
The half life of dextroamphetamine is about 9 to 11 hours.
Clearance
Dextroamphetamine has an apparent clearance of about 0.9 L/kg/h.
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