Desogestrelum
Desogestrelum Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Desogestrelum is a brand name. Its generic name is Desogestrel.
Desogestrelum Introduction
Desogestrelum is a progestin hormone that is used for contraception and is a derivative of the naturally occurring hormone progesterone. It is used in the manufacture of desogestrel as an active ingredient in combination with ethinylestradiol for use in oral contraceptive tablets.
Desogestrelum Uses
Desogestrelum is primarily used for contraception and is also used to treat heavy menstrual bleeding, endometriosis, and breast pain. It is also used in combination with other hormones to treat menopausal symptoms.
Desogestrelum Mechanism of Action
Desogestrelum works by suppressing ovulation and, in cases of endometriosis, focuses on reducing the concentrations of estrogen responsible for stimulating the growth of endometrial tissue.
How Long Does it Take for Desogestrelum to Work?
Desogestrelum typically works within 24-48 hours after administration and the effects can last up to three to six months.
Desogestrelum Absorption
Desogestrelum is rapidly absorbed from the gastrointestinal tract and has a bioavailability of approximately 50-80%. The peak plasma concentration of desogestrel is achieved after approximately four to five hours.
Desogestrelum Route of Elimination
Desogestrelum is excreted via the urine and feces as metabolites. Approximately 30% is excreted in the urine, while the remainder is excreted via the feces.
Desogestrelum Dosage
The recommended dosage of desogestrel varies based on the indication: for contraception use, the starting dose is 30 mcg once daily for 21 consecutive days followed by a 7-day rest period. For treatment of endometriosis, the recommended dose is 30 mcg twice a day for 21 consecutive days. For treatment of PMS symptoms, the recommended dose is 30 mcg once daily for 21 consecutive days.
Desogestrelum Administration
Desogestrelum can be taken with or without food. It is recommended to take it at the same time each day to maintain effectiveness.
Desogestrelum Side Effects
Common side effects of desogestrel include nausea, headache, breast tenderness, bloating, and breakthrough bleeding. If any of these side effects do not improve or are bothersome, it is recommended to speak to a doctor. Rare but serious side effects include an increased risk of blood clots, stroke, and heart attack.
Desogestrelum Toxicity
There is no established threshold for desogestrel toxicity. However, if large doses are taken, the symptoms may be similar to those of an overdose of other steroid hormones, such as dizziness, headache, nausea, vomiting, and sluggishness.
Desogestrelum Precautions
Desogestrelum should be used with caution in women with a history of cardiovascular disease, diabetes, hypertension, liver disease, or thromboembolic disorders. Women should also not take the medication if they are pregnant or breastfeeding.
Desogestrelum Interactions
Desogestrelum interacts with certain drugs, such as anticonvulsants, protease inhibitors, certain antibiotics, antifungals, and St. John's wort. It is important to tell a doctor about any other medications being taken before starting desogestrel.
Desogestrelum Disease Interaction
Desogestrelum may interact with certain diseases, such as liver disease, cardiovascular disease, diabetes, hypertension, or thromboembolic disorders. It is important to inform a doctor of any pre-existing health conditions before starting desogestrel.
Desogestrelum Drug Interactions
Desogestrelum may interact with certain drugs and affect their metabolism or activity. These drugs include anticonvulsants, protease inhibitors, certain antibiotics, antifungals, and St. John's wort.
Desogestrelum Food Interactions
There are no known food interactions with desogestrel.
Desogestrelum Use in Pregnancy
Desogestrelum should not be used during pregnancy as it may cause harm to a developing fetus. Women are advised to avoid becoming pregnant while taking desogestrel.
Desogestrelum Use in Lactation
Desogestrelum should not be used during lactation as it can be passed to an infant through the breastmilk and may cause adverse effects in a nursing infant.
Desogestrelum Acute Overdose
If an overdose of desogestrel is suspected, seek medical attention immediately. If taken orally, the symptoms may be similar to other steroid hormones, such as dizziness, headache, nausea, vomiting, and sluggishness.
Desogestrelum Contraindication
Desogestrelum is contraindicated in women with a history of thromboembolic disorders, breast cancer, or other hormone-sensitive cancer.
Desogestrelum Use Directions
Desogestrelum should be taken as directed by a doctor. Do not increase or decrease the dose without medical advice. Follow the directions on the package insert and take the medication as prescribed.
Desogestrelum Storage Conditions
Desogestrelum should be stored at room temperature and away from light and moisture. Keep the medication out of the reach of children.
Desogestrelum Volume of Distribution
The volume of distribution for desogestrel is approximately 3.7 L/kg.
Desogestrelum Half Life
The half-life of desogestrel is approximately 17-24 hours.
Desogestrelum Clearance
The average clearance of desogestrel is approximately 6 L/hr/kg.
Here you find in details version of Desogestrelum
Some Frequently Asked Questions About Desogestrelum
1. What is Desogestrelum?
Desogestrelum is a form of progesterone used as a contraceptive to prevent unwanted pregnancies. It is available as a combination oral contraceptive pill, usually prescribed in combination with ethinyl estradiol.
2. How does Desogestrelum work?
Desogestrelum blocks the release of the egg during ovulation, and also thickens the cervical mucus making it more difficult for sperm to get to the egg. This makes it much more difficult for a sperm to fertilize an egg.
3. Who should not use Desogestrelum?
Desogestrelum should not be taken by women who have had a history of blood clots or other associated conditions. Women who are pregnant, breastfeeding, or expecting to become pregnant should not take Desogestrelum. Women who have uncontrolled hypertension, diabetes, or active liver disease should also avoid Desogestrelum.
4. How is Desogestrelum taken?
Desogestrelum is generally taken orally in pill form. It is important to take the pill at the same time each day, and to stay on schedule. Missing any doses may decrease the efficacy of the medication in preventing pregnancy.
5. What are some common side effects of Desogestrelum?
Common side effects of Desogestrelum include nausea, vomiting, breast tenderness, headache, changes in weight, changes in libido, and spotting. Less common side effects include dizziness, hair loss, and changes in skin tone.
6. Are there any other medications or conditions that might interact negatively with Desogestrelum?
Yes, there are certain medications or conditions that can interact with Desogestrelum. These include certain antibiotics, seizure medications, HIV medications, and tuberculosis medications. Women who have a history of blood clots or other associated medical conditions should not take Desogestrelum.
7. What should I do if I miss a dose of Desogestrelum?
If you miss a dose of Desogestrelum, take it as soon as you remember. If you do not remember until it is time for your next dose, just take the next dose as usual. Do not take a double dose to make up for the missed dose.
8. Are there any other methods of birth control that Desogestrelum can be combined with?
Yes, Desogestrelum can be combined with other methods of birth control such as condoms, diaphragms, and other non-hormonal contraceptives. It is important to use a back-up method of contraception if you are using Desogestrelum.
9. Can Desogestrelum be used while breastfeeding?
No, desogestrel should not be used while breastfeeding as it may reduce the amount of milk produced. It is advised to wait until after breastfeeding is finished, and then start using Desogestrelum.
10. How long does it take for Desogestrelum to become effective?
Desogestrelum typically becomes effective as a birth control method within 24 hours of taking the first dose. However, it is important to use a back-up method of contraception for the first seven days of taking Desogestrelum in order to ensure maximum protection.
11. How long does it take for the effects of Desogestrelum to wear off?
The effects of Desogestrelum typically wear off within 48 hours after the last dose is taken. It is important to remember to start taking the next packet of Desogestrelum on schedule in order to stay protected.
12. What are the possible risks and complications associated with taking Desogestrelum?
The most common risks and complications associated with taking Desogestrelum include an increased risk of blood clots, stroke, and heart attack. It is important for women to talk to their doctor about any medical conditions and medications they are taking in order to reduce the risk of complications.
13. Does Desogestrelum increase the risk of breast cancer?
No, according to the World Health Organization, Desogestrelum does not increase the risk of breast cancer. It is important to note that the risk of Breast Cancer increases with age, and women over the age of 35 should talk to their doctor about their birth control options.
14. How long can a woman take Desogestrelum?
A woman can take Desogestrelum for as long as she needs to in order to prevent unwanted pregnancies. However, if she experiences any side effects or complications while taking Desogestrelum, it is important to talk to her doctor as soon as possible.
15. Does Desogestrelum affect fertility?
No, Desogestrelum does not affect fertility. After discontinuing the use of Desogestrelum, the natural ovulation and fertility process should resume as normal.
16. Is Desogestrelum safe for women over the age of 35?
Yes, Desogestrelum can be taken safely by women over the age of 35, as long as they do not have any medical conditions that could put them at an increased risk of complications. It is still important to talk to a healthcare provider before starting any birth control.
17. Can Desogestrelum be used to treat any other medical conditions?
No, Desogestrelum is not recommended for the treatment of any medical condition other than contraception. Other medications or treatments should be discussed with a healthcare provider.
18. Are there any over-the-counter products that contain Desogestrelum?
No, Desogestrelum is only available with a prescription from a healthcare provider. Over-the-counter products without Desogestrelum may be available, but it is important to discuss your options with a healthcare provider.
19. How long will it take for the body to adjust to Desogestrelum?
It typically takes the body up to three months to adjust to any new medication. During the first three months, it is normal to experience some side effects such as nausea, headache, and breast tenderness.
20. Does Desogestrelum need to be taken with food?
No, Desogestrelum can be taken with or without food. However, it is important to make sure that it is taken at the same time each day in order to stay protected.
21. Does Desogestrelum increase the risk of depression?
There is some evidence that Desogestrelum can increase the risk of depression in some individuals. It is important to discuss any concerns or changes in mood with a healthcare professional.
22. Can Desogestrelum interact with any herbal supplements?
Yes, Desogestrelum can interact with certain herbal supplements, so it is important to discuss all medications and supplements with a healthcare professional before taking Desogestrelum.
23. Is Desogestrelum covered by most insurance providers?
Yes, most insurance providers recognize Desogestrelum as an accepted form of birth control and have plans that cover it.
24. Can Desogestrelum cause breakthrough bleeding?
It is possible for Desogestrelum to cause breakthrough bleeding. If this occurs, it is important to discuss it with a healthcare provider in order to rule out any other potential causes of the bleeding.
25. What should be done if the pills are missed or vomited after taking them?
If a dose is missed or vomited after taking it, it is important to take a precautionary method of birth control such as condoms or a diaphragm until the next packet is started. If more than one dose is missed, it is important to consult a healthcare professional.
26. Does Desogestrelum interact with alcohol?
No, Desogestrelum does not interact with alcohol, but it is still important to drink responsibly and not over-consume alcohol while on birth control.
27. Is it safe to take Desogestrelum while traveling?
Yes, it is safe to take Desogestrelum while travelling as long as you do not miss any doses. If you will be travelling across different time zones, it is important to maintain the same schedule of taking the pill.
28. Can Desogestrelum help with acne?
Yes, in some cases Desogestrelum can help with mild to moderate acne by reducing the amount of sebum produced by the skin. It is important to discuss any acne concerns with a healthcare professional.
29. Is Desogestrelum covered by Medicaid?
Yes, most states provide coverage for Desogestrelum through Medicaid. It is important to contact your local Medicaid office to discuss coverage options.
30. Is it safe to take Desogestrelum while breastfeeding?
No, Desogestrelum should not be taken while breastfeeding as it may reduce the amount of milk produced. It is advised to wait until after breastfeeding is finished, and then start using Desogestrelum.