Crotamiton

Crotamiton Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Crotamiton is a brand name. Its generic name is Crotamiton.

Introduction

Crotamiton is a topical medication used to relieve itching and burning caused by skin irritation and itching skin conditions. It is a monoethanolamine derivative that is structurally related to carbamate pesticides.

Uses

Crotamiton is used in symptomatic relief of itching and burning due to certain skin conditions such as:
  • Contact dermatitis
  • Eczema
  • Insect bites
  • Poison ivy
  • Shingles

Mechanism of Action

Crotamiton works by suppressing the release of histamine from mast cells. Histamine is responsible for allergic reaction and inflammatory response. Crotamiton also inhibits the production of leukotrienes, thereby suppressing further inflammatory response.

How Long Does it Take to Work?

The effects of crotamiton can be seen within a few minutes of applying the cream to the affected area. It can take up to 24 hours for the full effects of the drug to be seen.

Absorption

Crotamiton is poorly absorbed when applied topically to intact skin. When applied to broken or damaged skin, it is more readily absorbed.

Route of Elimination

Crotamiton is rapidly metabolized by the liver and excreted from the body in the urine.

Dosage

The usual adult dosage of Crotamiton is 10% in an ointment, cream, or lotion. It should be applied to the affected area two to three times per day. In children, the usual dose of Crotamiton is 10% cream, ointment, or lotion applied to the affected area 2-3 times daily. The dosage for children should be determined by the physician.

Administration

Crotamiton should be applied topically to the affected area two to three times daily. It should be applied to completely dry skin and gently rubbed in until it is fully absorbed. It should not be applied to broken skin.

Side Effects

Possible side effects of Crotamiton include:
  • Skin irritation
  • Itchiness
  • Redness
  • Stinging
  • Burning sensation
  • Allergic reaction (including rash and hives)

Toxicity

When taken as prescribed, Crotamiton has a low risk of toxicity. If too much is taken, it can cause skin irritation and burning.

Precautions

Crotamiton should not be used over large areas of the body. It should be applied sparingly and only to the affected areas. It should not be applied to open wounds or broken skin.

Interactions

Crotamiton may interact with certain drugs, which can cause side effects or make the medication less effective. It is important to talk to your doctor or pharmacist before taking this medication.

Disease Interaction

Crotamiton should not be used by people with a known allergy or hypersensitivity to the drug. It should not be used by people with liver, kidney, or heart disease as it may cause an exaggerated response.

Drug Interaction

Crotamiton may interact with certain drugs, which can cause side effects or make the medication less effective. It is important to talk to your doctor or pharmacist before taking this medication.

Food Interactions

Crotamiton is not known to interact with food.

Pregnancy Use

Crotamiton is not recommended for use during pregnancy. If you are pregnant, talk to your doctor before taking this medication.

Lactation Use

Crotamiton is not recommended for use during lactation. If you are breastfeeding, talk to your doctor before taking this medication.

Acute Overdose

If an acute overdose of Crotamiton is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include burning, stinging, and skin irritation.

Contraindication

Crotamiton should not be used by people with a known allergy or hypersensitivity to the drug. It should not be used by people with liver, kidney, or heart disease as it may cause an exaggerated response.

Use Direction

Crotamiton should be applied topically to the affected area 2-3 times daily. It should be applied to completely dry skin and gently rubbed in until it is fully absorbed. It should not be applied to broken skin.

Storage Condition

Crotamiton should be stored at room temperature, away from light and moisture. Keep the medication away from children and pets.

Volume of Distribution

Crotamiton has a volume of distribution of 7-13 L/kg.

Half Life

The estimated half-life of crotamiton is 4-7 hours.

Clearance

The estimated clearance of crotamiton is 2.3-3.1 mL/min/kg.

Here you find in details version of Crotamiton

Some Frequently Asked Questions About Crotamiton

What is Crotamiton?

Crotamiton is a topical antipruritic medication used to treat itching associated with skin irritation and other conditions. It is available in both cream and lotion forms and is available over-the-counter for the relief of itching.

What is Crotamiton used for?

Crotamiton is used to treat itching associated with skin irritation and other conditions. It may also be used to prevent or reduce itching from insect bites, sunburns, minor cuts, scrapes, or burns.

Does Crotamiton have side effects?

While side effects are rare, Crotamiton can cause skin irritation, redness, or burning, especially when used over large areas of the body or for long periods of time. If these or other side effects develop, contact a healthcare professional immediately.

Is Crotamiton safe for pregnant or breastfeeding women?

Crotamiton should not be used by pregnant or breastfeeding women unless directed by a healthcare professional. People with kidney or liver disease should also use it only under a doctor’s supervision.

Can I take Crotamiton with other medications?

Always check with a healthcare professional before starting any new medications. Crotamiton may interact with certain other medications, including antibiotics, antifungals, and corticosteroids. These interactions can increase the risk of side effects or reduce the effectiveness of the medications.

How often should I use Crotamiton?

Crotamiton is usually used twice a day, morning and night. If using the cream form, apply a thin layer to the affected area and gently massage it into the skin until it is fully absorbed.

How long does it take for Crotamiton to take effect?

Crotamiton typically begins to take effect within a few hours and maintenance doses usually provide relief for several days up to a week. If after using the medication for this long, your symptoms have not improved, contact a healthcare professional.

How long can I use Crotamiton for?

Crotamiton should not be used for more than 10 days. If your symptoms persist beyond that time, contact a healthcare professional.

Can Crotamiton be used on other areas of the body?

Crotamiton is intended for use on the skin only and should not be applied to the eyes, nose, or mouth. Avoid contact with the eyebrows, eyelashes, or other mucous membranes.

Is Crotamiton available in other forms?

In addition to the cream and lotion forms, Crotamiton is also available in ointment, powder, and spray formulations.

Can I use Crotamiton on my face?

If you are using the cream or lotion forms, it is generally safe to apply it to your face. If using the spray form, do not spray directly on the face, as it may cause skin irritation and redness. Spray it onto a cotton ball or tissue and apply it to the face.

When should Crotamiton not be used?

Crotamiton should not be used for more than 10 days, unless directed by a healthcare professional. It should not be used on broken skin or in the eyes, nose, or mouth. It should also not be used on children under the age of 2.

Is Crotamiton safe for children?

Crotamiton should not be used on children under the age of 2, unless directed by a healthcare professional. Children over 2 years of age should use the medication under the direction and supervision of a healthcare professional.

Is Crotamiton addictive?

Crotamiton is not considered to be addictive and is generally considered safe for long-term use. However, if you experience any side effects or your symptoms do not improve, contact a healthcare professional.

Does Crotamiton help with insect bites?

Yes, Crotamiton can be used to provide relief from itching caused by insect bites. It can also be used to prevent itching from insect bites, sunburns, minor cuts, scrapes, or burns.

Can I use Crotamiton on sunburns?

Yes, Crotamiton can be used to provide relief from itching caused by sunburns. It can also be used to prevent itching from insect bites, sunburns, minor cuts, scrapes, or burns.

Does Crotamiton work instantly?

Crotamiton typically begins to take effect within a few hours of application, and doses usually provide relief for several days up to a week. If your symptoms have not improved after using the medication for this long, contact a healthcare professional.

Does Crotamiton have any other uses?

Crotamiton is also occasionally used to treat scabies, an itchy skin condition caused by mites. It is important to always follow the dosing instructions provided by your healthcare professional when using Crotamiton for this purpose.

Can I use Crotamiton while pregnant?

Crotamiton should not be used by pregnant women unless directed by a healthcare professional. People with kidney or liver disease should also use it only under a doctor’s supervision.

Can I use Crotamiton while breastfeeding?

Crotamiton should not be used by breastfeeding women unless directed by a healthcare professional. People with kidney or liver disease should also use it only under a doctor’s supervision.

Is Crotamiton available as an over-the-counter medication?

Yes, Crotamiton is available over-the-counter in both cream and lotion forms for the relief of itching.

What should I do if I experience side effects while using Crotamiton?

If you experience any side effects while using Crotamiton, such as skin irritation, redness, burning, or swelling, contact a healthcare professional immediately.

How do I apply Crotamiton?

If using the cream or lotion form, apply a thin layer to the affected area and gently massage it into the skin until it is fully absorbed. For the ointment, powder, and spray forms, refer to the instructions on the packaging for proper application.

Is Crotamiton the same as hydrocortisone?

No, Crotamiton and hydrocortisone are not the same. Crotamiton is an antipruritic medication used to treat itching associated with skin irritation and other conditions, while hydrocortisone is a corticosteroid medication used to treat inflammation, itching, irritation, and other skin conditions.

Can I use Crotamiton in combination with other medications?

Always check with a healthcare professional before starting any new medications. Crotamiton may interact with certain other medications, including antibiotics, antifungals, and corticosteroids. These interactions can increase the risk of side effects or reduce the effectiveness of the medications.

Does Crotamiton cause drowsiness?

No, Crotamiton does not typically cause drowsiness. If you experience drowsiness while using Crotamiton, contact a healthcare professional immediately.

Can Crotamiton be used to treat acne?

No, Crotamiton should not be used to treat acne. If you are experiencing acne, contact a healthcare professional for advice on appropriate treatment.

Is Crotamiton safe for long-term use?

Yes, Crotamiton is generally considered safe for long-term use. However, if you experience any side effects or your symptoms do not improve, contact a healthcare professional.

Does Crotamiton need to be refrigerated?

No, Crotamiton does not need to be refrigerated. It should be stored at a temperature between 19-25°C and kept away from direct sunlight and heat.

Do I need a prescription to get Crotamiton?

Crotamiton is available over-the-counter in both cream and lotion forms for the relief of itching, so a prescription is not needed.

Can I use Crotamiton on an open wound?

No, Crotamiton should not be used on broken skin or open wounds. If you have an open wound, contact a healthcare professional for advice on appropriate treatment.

Can Crotamiton be used on the scalp?

Yes, Crotamiton can be used on the scalp. However, avoid contact with the eyebrows, eyelashes, or other mucous membranes.

Can I use Crotamiton on eczema?

Yes, Crotamiton can be used to provide relief from itching caused by eczema. However, if your symptoms have not improved after using the medication for 10 days, contact a healthcare professional for advice.

Will Crotamiton help with itchy skin?

Yes, both the cream and lotion formulations of Crotamiton are used to treat itching associated with skin irritation and other conditions. It may also be used to prevent or reduce itching from insect bites, sunburns, minor cuts, scrapes, or burns.

Can I use Crotamiton on my lips?

No, Crotamiton should not be applied to the lips or other mucous membranes, as it may cause skin irritation and redness. If you are experiencing itching on your lips, contact a healthcare professional for advice on appropriate treatment.

Can I use Crotamiton on a rash?

Yes, Crotamiton can be used to provide relief from itching caused by a rash. It may also be used to prevent or reduce itching from insect bites, sunburns, minor cuts, scrapes, or burns.

Can Crotamiton be used on open sores?

No, Crotamiton should not be used on broken skin or open sores. If you have open sores, contact a healthcare professional for advice on appropriate treatment.

What should I do if I miss a dose of Crotamiton?

If you miss a dose, apply it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular dosing schedule.

Can I use too much Crotamiton?

Using too much Crotamiton can cause skin irritation, redness, or burning. If you experience any of these symptoms after applying the medication, wash it off with soap and water and contact a healthcare professional immediately.

What should I do if Crotamiton gets in my eyes?

If Crotamiton gets into your eyes, rinse it out with plenty of cool water and contact a healthcare professional immediately. Do not use Crotamiton on or near the eyes, nose, or mouth.

Can Crotamiton cause allergic reactions?

Yes, Crotamiton can cause allergic reactions, such as skin irritation, redness, burning, or swelling. If you experience any of these symptoms after using Crotamiton, discontinue use and contact a healthcare professional immediately.