Cosentyx
Cosentyx Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Cosentyx is a brand name. Its generic name is Secukinumab.
Introduction
Cosentyx is a monoclonal antibody used to treat active ankylosing spondylitis, psoriatic arthritis, and plaque psoriasis. It is also known as Cosentyx. It is administered into the body by injections.Uses
Cosentyx is used to treat active ankylosing spondylitis, psoriatic arthritis, and plaque psoriasis. It helps to reduce redness and swelling of these conditions, as well as providing relief from stiffness and improving mobility.Mechanism of Action
Cosentyx works by targeting and blocking interleukin-17A (IL-17A), a protein which has been linked to inflammation. By blocking the action of this protein, secukinumab is able to reduce inflammation in the body, thereby relieving some of the symptoms associated with these conditions.How Long Does It Take to Work?
Cosentyx is usually effective after two or three doses. After a few weeks, patients can start to experience relief from symptoms associated with the condition.Absorption
Cosentyx is quickly absorbed into the body.Route of Elimination
Cosentyx is primarily eliminated through the kidneys.Dosage
For active ankylosing spondylitis: The recommended dose is 150 mg at weeks 0, 1, 2, 4, 8, and 12 followed by 150 mg every 4-weeks after that or 150 mg at weeks 0, 1, 2, 4, and 12 and 300 mg every 4-weeks after that. For psoriatic arthritis and plaque psoriasis: The recommended dose is 75 mg at weeks 0, 1, 2, 4, 8, and 12 followed by 150 mg every 4 weeks after that.Administration
Cosentyx is administered through intramuscular injections.Side Effects
Common side effects of secukinumab include nausea, upper respiratory tract infections, headaches, and pain at the injection site. Other serious side effects, such as serious allergic reactions, skin cancer, and inflammatory bowel disease, have been reported in rare cases.Toxicity
Cosentyx has not been shown to be toxic when used as directed.Precautions
Patients should not use secukinumab if they have a history of certain types of cancer, including lymphoma. Patients should also inform their doctor if they have had or are currently being treated for an infection.Interactions
Cosentyx should not be used with certain medications, especially drugs that suppress the immune system, such as corticosteroids or other immunosuppressants. Patients should talk to their doctor about potential drug interactions before use.Disease Interactions
Cosentyx should not be used in patients with active tuberculosis or other infections.Drug Interactions
Cosentyx is known to interact with certain other medications. Patients should talk to a doctor about potential drug interactions before using secukinumab.Food Interactions
There are no known food interactions with secukinumab.Pregnancy Use
Cosentyx should not be used by pregnant women, as it has not been studied in pregnant patients.Lactation Use
Cosentyx should not be used by breastfeeding women, as it has not been studied in lactating patients.Acute Overdose
There is no specific treatment for an overdose with secukinumab.Contraindications
Cosentyx should not be used in patients with a history of certain types of cancer, such as lymphoma, or in patients with active tuberculosis or other infections.Use Directions
Cosentyx should be administered according to the instructions of a doctor.Storage Conditions
Cosentyx should be stored at temperatures between 20°C and 25°C. It also should be kept out of reach of children.Volume of Distribution
The volume of distribution for secukinumab is not known.Half Life
The half-life of secukinumab is approximately 26.8 days.Clearance
The clearance rate of secukinumab is not known.Here you find in details version of Cosentyx
Some Frequently Asked Questions About Cosentyx
https://www.medicinesfaq.com/brand/cosentyx,
http://www.genome.jp/dbget-bin/www_bget?drug:D09967,
https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=347910391,
https://mor.nlm.nih.gov/RxNav/search?searchBy=RXCUI&searchTerm=1599788,
https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL1743068,
http://www.rxlist.com/cosentyx-drug.htm,
https://www.drugs.com/cdi/secukinumab.html,
https://en.wikipedia.org/wiki/Secukinumab,