Co-Valset

Co-Valset Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Co-Valset is a brand name. Its generic name is Valsartan + Hydrochlorothiazide.

Introduction

Co-Valset is a combination drug that is used to treat hypertension (high blood pressure). It is used when alone treatment with either drug has not been effective or if the patient's doctor decides that a combination drug is best for them.

Uses

Co-Valset is an antihypertensive medicine, used for the treatment of essential hypertension. The drug is also used for the treatment of edema (fluid retention).

Mechanism of action

Valsartan is an angiotensin receptor blocker (ARB) and works by blocking the effects of angiotensin II. Angiotensin II is a hormone that narrows blood vessels and increases blood pressure. By blocking the action of angiotensin II, Valsartan causes the blood vessels to relax which decreases blood pressure and improves blood flow. Hydrochlorothiazide is a diuretic (water pill) and works by increasing the amount of water and sodium that is excreted in the urine. This increased urine output decreases the amount of water in the body, which reduces blood volume, which causes a decrease in blood pressure.

How long does it take to work?

Although individual patient response will vary, it usually takes 2-4 weeks for Co-Valset to reach a therapeutic effect on blood pressure.

Absorption

No information available.

Route of elimination

Co-Valset is primarily eliminated through the kidneys, with approximately 66% of its metabolites excreted via the urine.

Dosage

Co-Valset is available in tablets containing 80 mg of valsartan and 12.5 mg of hydrochlorothiazide, and 160 mg of valsartan and 12.5 mg of hydrochlorothiazide. Patients should take Co-Valset exactly as their doctor has prescribed.

Administration

Co-Valset should be taken orally once daily with or without food.

Side effects

Common side effects of Co-Valset include dizziness, lightheadedness, headache, tiredness, nausea, diarrhea, and rash. These side effects are usually mild and will go away with time. In rare cases, more serious side effects can occur, such as fainting, severe low blood pressure, and difficulty breathing. If these side effects occur, the patient should seek medical attention immediately.

Toxicity

Co-Valset is not typically toxic if taken as prescribed by the doctor. However, if the drug is taken in large doses, it can lead to serious and potentially life-threatening conditions, including low blood pressure, electrolyte imbalances, and kidney damage.

Precautions

Patients on Co-Valset should not stop taking the drug without consulting with their doctor. The drug can cause a sudden worsening of blood pressure if stopped abruptly.

Interactions

Co-Valset can interact with other medicines and supplements, so patients should always let their doctor know of any other medicines or supplements they are taking.

Disease Interactions

Patients with kidney disease, liver disease, heart disease, or diabetes should discuss with their doctor whether Co-Valset is safe for them to take.

Drug Interactions

Co-Valset can interact with other drugs and should be used with caution in patients taking ACE inhibitors, ARBs, lithium, probenecid, and nonsteroidal anti-inflammatory drugs (NSAIDs).

Food Interactions

No information available.

Pregnancy Use

Co-Valset should not be taken by pregnant women. This drug can cause birth defects and harm an unborn baby.

Lactation Use

Co-Valset is excreted in breast milk and should not be used by nursing mothers.

Acute Overdose

Signs of an acute overdose may include low blood pressure, difficulty breathing, dizziness, and fainting. If an overdose is suspected, seek medical help immediately.

Contraindication

Co-Valset should not be used by patients who are hypersensitive to either valsartan or hydrochlorothiazide.

Use Direction

Co-Valset should be taken exactly as prescribed by the doctor. Patients should not adjust their dose or cease taking the drug without consulting with their doctor.

Storage Condition

Co-Valset should be stored at room temperature, away from moisture and heat.

Volume of Distribution

No information available.

Half Life

Valsartan has a half-life of approximately 6 hours, with a range of 2.3 to 8 hours. Hydrochlorothiazide has a half-life of approximately 6.3 hours, with a range of 1.5 to 25.6 hours.

Clearance

No information available.

Here you find in details version of Co-Valset

Some Frequently Asked Questions About Co-Valset

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What is Co-Valset?

Co-Valset is a combination medication, containing the drugs valsartan and hydrochlorothiazide. Valsartan is an angiotensin-receptor blocker, which works to relax the muscles of the blood vessels. Hydrochlorothiazide is a type of diuretic, which helps to reduce the amount of fluid in the body.

What is the purpose of taking Co-Valset?

Co-Valset is used to treat high blood pressure. This combination medication works to relax the muscles of the blood vessels and reduce the amount of fluid in the body to help lower blood pressure.

How do I take Co-Valset?

Co-Valset should be taken exactly as prescribed by your doctor. Generally, the medication is taken once a day. It is important to take the medication at approximately the same time each day and to not miss any doses.

What are the possible side effects of taking Co-Valset?

Common side effects of taking Co-Valset include headache, tired feeling, weakness, drowsiness, nausea, vomiting, upset stomach, increased urination, muscle cramps, itching, joint pain, and blurred vision. If these side effects become severe, contact your doctor.

Who should not take Co-Valset?

Co-Valset is not suitable for everyone. People who are allergic to either valsartan or hydrochlorothiazide should not take Co-Valset. It is important to inform your doctor about any medications you are currently taking, as some medications can interact negatively with Co-Valset.

Is Co-Valset safe during pregnancy?

There is not enough research to determine whether Co-Valset is safe during pregnancy. It is important to speak with your doctor before taking Co-Valset if you are pregnant or trying to become pregnant.

What should I do if I miss a dose of Co-Valset?

If you miss a dose of Co-Valset, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose as scheduled. It is important not to double the dose.

Can I take Co-Valset with other medications?

It is important to speak with your doctor before taking Co-Valset with other medications, as some medications can interact negatively with Co-Valset. These include other blood pressure medications, NSAIDs, antivirals, antifungals, lithium, and digoxin.

Can I drink alcohol while taking Co-Valset?

Drinking alcohol while taking Co-Valset is not recommended, as alcohol can increase the risk of side effects such as lightheadedness and fainting. It is important to consult with your doctor before drinking alcohol while taking Co-Valset.

When should I stop taking Co-Valset?

Co-Valset should generally be taken as prescribed by your doctor. If you experience severe side effects, it is important to contact your doctor, who may advise to stop taking the medication. You should never stop taking Co-Valset without first speaking to your doctor.

What should I do if I experience an allergic reaction while taking Co-Valset?

If you experience an allergic reaction while taking Co-Valset, stop taking the medication right away and seek medical help. Symptoms of an allergic reaction include hives, difficulty breathing, and swelling of the face, tongue, and throat.

What should I do if I experience chest pain while taking Co-Valset?

If you experience chest pain while taking Co-Valset, stop taking the medication right away and seek medical help. Chest pain is a potential side effect of taking Co-Valset.

Can I take Co-Valset to treat a cough?

No, Co-Valset should not be taken to treat a cough. Co-Valset is a medication used to treat high blood pressure, not a cough.

Can children take Co-Valset?

No, Co-Valset is not suitable for children. Co-Valset is only approved for use in adults.

Can I take Co-Valset if I have diabetes?

Yes, you can take Co-Valset if you have diabetes. However, it is important to let your doctor know that you have diabetes, as some medications can interact negatively with Co-Valset.

What happens if I take an overdose of Co-Valset?

If you take an overdose of Co-Valset, it is important to seek medical help right away. Symptoms of an overdose can include nausea, vomiting, dizziness, and fainting.

What should I do if I forget to take my dose of Co-Valset?

If you forget to take a dose of Co-Valset, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose as scheduled. It is important not to double the dose.

Can I take Co-Valset if I have a kidney condition?

Yes, you can take Co-Valset if you have a kidney condition. However, it is important to consult with your doctor before taking the medication. Your doctor may need to adjust your dose or monitor your kidney condition more closely.

Can Co-Valset cause weight gain?

Co-Valset has not been proven to cause weight gain. However, if you are experiencing abnormal weight gain while taking Co-Valset, it is important to consult with your doctor.

Can Co-Valset cause dry mouth?

Yes, Co-Valset can cause dry mouth. If you experience dry mouth while taking Co-Valset, it is important to speak with your doctor.

Can I take Co-Valset if I am breastfeeding?

No, Co-Valset is not suitable for breastfeeding women. It is important to consult with your doctor if you are breastfeeding before taking Co-Valset.

What should I do if I experience dizziness while taking Co-Valset?

If you experience dizziness while taking Co-Valset, it is important to speak with your doctor. You may need to have your dose adjusted or you may need to stop taking the medication.

Are there any dietary restrictions while taking Co-Valset?

No, there are no dietary restrictions while taking Co-Valset. However, it is important to speak with your doctor before making any major changes to your diet, as some dietary factors may affect the effectiveness of the medication.

What should I do if I experience diarrhea while taking Co-Valset?

If you experience diarrhea while taking Co-Valset, it is important to contact your doctor. Diarrhea is a potential side effect of taking this medication.

What should I do if I experience joint pain while taking Co-Valset?

If you experience joint pain while taking Co-Valset, it is important to contact your doctor. Joint pain is a potential side effect of taking this medication.

Can I take Co-Valset while pregnant?

There is not enough research to determine whether Co-Valset is safe during pregnancy. It is important to speak with your doctor before taking Co-Valset if you are pregnant or trying to become pregnant.

How quickly does Co-Valset work?

Co-Valset begins working right away. However, it may take several weeks for the full effects of the medication to be reached.

Can Co-Valset cause hair loss?

Co-Valset has not been proven to cause hair loss. However, if you are experiencing abnormal hair loss while taking Co-Valset, it is important to consult with your doctor.

Is it safe to take Co-Valset with other blood pressure medications?

No, it is not safe to take Co-Valset with other blood pressure medications. It is important to speak with your doctor before taking Co-Valset with other medications, as some medications can interact negatively with Co-Valset.

Can I take Co-Valset if I have liver disease?

Yes, you can take Co-Valset if you have liver disease. However, it is important to consult with your doctor before taking the medication. Your doctor may need to adjust your dose or monitor your liver condition more closely.

What should I do if my blood pressure does not improve while taking Co-Valset?

If your blood pressure does not improve while taking Co-Valset, it is important to contact your doctor. Your doctor may need to adjust your dose or try a different medication to help lower your blood pressure.

Does Co-Valset interact with any other medications?

Yes, Co-Valset can interact with other medications. It is important to speak with your doctor before taking Co-Valset with other medications, as some medications can interact negatively with Co-Valset. These include other blood pressure medications, NSAIDs, antivirals, antifungals, lithium, and digoxin.

Can Co-Valset be used to treat heart failure?

No, Co-Valset should not be used to treat heart failure. Co-Valset is a medication used to treat high blood pressure, not heart failure.

Does Co-Valset cause fatigue?

Yes, Co-Valset can cause fatigue. If you experience fatigue while taking Co-Valset, it is important to contact your doctor. Your doctor may need to adjust your dose or switch you to a different medication.

Does Co-Valset cause insomnia?