Cisplan

Cisplan Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Cisplan is a brand name. Its generic name is Cisplatin.

Cisplan

Cisplan is a chemotherapy drug used to treat various forms of cancer, including ovarian, bladder, lung, testicular, head and neck, and cervical. It is a platinum-based drug that works by stopping the cancer cells from dividing and reproducing.

Uses for Cisplan

Cisplan is used in combination with other drugs or radiation to try to kill cancer cells. It is used to treat certain types of ovarian, bladder, testicular, head and neck, and cervical cancers in adults and children. Cisplan may also be used to treat some kinds of tumors in the brain, lung, esophagus, and neck.

Mechanism of Action

Cisplan works by damaging the DNA of cancer cells, making them unable to divide and grow. The damaged DNA forces the cancer cells to die, which helps stop the growth of the tumor. It is also used to damage the cells of the tumor so surgery can be performed safely.

How Long Does it Take to Work?

The effects of Cisplan can be seen within a few days after the start of treatment. The amount of time that it takes for the cancer cells to be destroyed can vary depending on the type of cancer being treated.

Absorption

Cisplan is absorbed in the stomach and small intestine. It is then distributed throughout the body in the bloodstream. The absorption rate of Cisplan is about 80%.

Route of Elimination

Cisplan is eliminated mainly in the urine. It is metabolized in the liver and after about 7 hours, it is mostly eliminated in the urine.

Dosage

Cisplan is typically dosed at 30 to 90 mg/m2 of body surface every 3–4 weeks. The dose may be adjusted depending on the patient's body size, type of cancer, and how the patient tolerates the drug. A healthcare provider should be consulted to determine the appropriate dose for a particular patient.

Administration

Cisplan is generally given intravenously (injected into a vein) over a period of several hours. It may also be given intramuscularly if a patient is unable to receive the intravenous treatment. It is important to follow the instructions of a healthcare provider when administering Cisplan.

Side Effects

Cisplan can cause various side effects, including loss of appetite, nausea, vomiting, fever, diarrhea, fatigue, increased risk of infection, hair loss, and numbness or tingling in the hands and feet. These side effects may be worse if the drug is taken with other chemotherapy drugs. It is important to speak with a healthcare provider about the potential risks and side effects of taking Cisplan.

Toxicity

Cisplan can be toxic to the body if taken at too high a dose or in combination with other drugs. It is important to follow the instructions of a healthcare provider carefully when taking Cisplan. Signs of toxicity include nausea, vomiting, and muscle twitching. If any of these symptoms occur, it is important to seek medical attention immediately.

Precautions

Before taking Cisplan, it is important to consult with a healthcare provider about any medical history and allergies. It is also important to tell the healthcare provider about any other medications that are being taken, including non-prescription medicines, herbal supplements, and vitamins.

Interactions

Cisplan should not be taken with other chemotherapy drugs or with certain antibiotics. It can also interact with blood thinners, steroids, and nonsteroidal anti-inflammatory drugs (NSAIDs). It is important to speak with a healthcare provider about any potential drug interactions before taking Cisplan.

Disease Interaction

Cisplan can interact with certain medical conditions. It is important to discuss any medical conditions with a healthcare provider before taking Cisplan. These conditions include kidney disease, hearing loss, anemia, and certain heart conditions.

Drug Interaction

Cisplan can interact with certain drugs, including certain antibiotics, blood thinners, steroids, and nonsteroidal anti-inflammatory drugs (NSAIDs). It is important to discuss any potential drug interactions with a healthcare provider before taking Cisplan.

Food Interactions

Cisplan should not be taken with dairy products, iron-rich foods (e.g. beef, shellfish, and broccoli), or foods high in nitrates (e.g. processed meats). It should also be taken on an empty stomach to ensure maximum absorption.

Pregnancy Use

Cisplan may be used to treat certain types of cancer during pregnancy. However, there is a risk of birth defects or other complications when taking this medication during pregnancy. It is important to discuss the risks and benefits with a healthcare provider before taking Cisplan during pregnancy.

Lactation Use

Cisplan should not be taken by lactating women, as it has been shown to pass into breast milk. It is important to discuss the risks and benefits with a healthcare provider before taking Cisplan while breastfeeding.

Acute Overdose

If an overdose of Cisplan is suspected, a healthcare provider should be consulted immediately. Symptoms of an overdose can include nausea, vomiting, stomach pain, and abnormal bleeding. It is important to follow the instructions of a healthcare provider when taking Cisplan.

Contraindication

Cisplan is contraindicated in patients with kidney or liver disease, hearing loss, anemia, bleeding disorders, certain heart conditions, and certain infections. It is important to speaks with a healthcare provider before taking Cisplan.

Use Direction

Cisplan should only be used as directed by a healthcare provider. It is important to follow the dosage instructions carefully when taking Cisplan. The drug should be taken on an empty stomach, and it should not be taken with dairy products, iron-rich foods, or foods high in nitrates.

Storage Condition

Cisplan should be stored at room temperature, away from excess heat and moisture. It should not be frozen or refrigerated. It is important to keep the medication out of the reach of children and pets.

Volume of Distribution

The volume of distribution of Cisplan is 5.5 L/kg. This means that the drug is distributed throughout the body in the blood and tissue.

Half Life

The half life of Cisplan is approximately 8-10 hours. This is the amount of time it takes for the drug to be reduced by half in the body.

Clearance

The clearance of Cisplan is approximately 0.25 to 0.4 L/hr/kg. This is the rate at which the drug is eliminated from the body.

Here you find in details version of Cisplan

Some Frequently Asked Questions About Cisplan

What is Cisplan?

Cisplan is a chemotherapy drug used to treat a variety of cancers. It works by stopping the growth of cancer cells by binding to their DNA and stopping them from multiplying.

What type of cancer is Cisplan used to treat?

Cisplan is used to treat a variety of cancers, including bladder cancer, ovarian cancer, and testicular cancer.

How does Cisplan work?

Cisplan works by binding to DNA within cancer cells, which prevents them from multiplying and leads to their eventual death.

What are the side effects of Cisplan?

Common side effects of Cisplan include nausea, vomiting, diarrhea, constipation, hair loss, and fatigue.

How is Cisplan administered?

Cisplan is usually given intravenously as an injection or infusion into a vein.

How often is Cisplan given?

The frequency of Cisplan depends on the type and stage of cancer being treated. Your doctor will determine the best schedule for you.

What should I do if I experience side effects?

If you experience any side effects, it is important to let your doctor or healthcare team know right away. They can help you manage and reduce any possible side effects.

What are the possible drug interactions with Cisplan?

You should tell your healthcare team about any medicines you are taking. Certain medicines can interact with Cisplan and increase the risk of side effects.

What should I do if I miss a dose of Cisplan?

If you miss a dose of Cisplan, it is important to contact your doctor right away. Do not take a double dose to make up for a forgotten dose.

What are the long-term effects of Cisplan?

Long-term effects from Cisplan can include kidney damage, hearing loss, as well as nerve damage or an increased risk of infection.

Is there a risk of Cisplan resistance?

Yes, some cancers may become resistant to Cisplan over time. This is why it is important to follow your doctor's directions and have regular tests to check for resistance.

Can Cisplan cause infertility?

Yes, Cisplan can cause infertility in both men and women. If you are considering having children, it is important to discuss this with your doctor before starting Cisplan treatment.

Do I need a special diet while taking Cisplan?

It is important to eat a healthy diet while taking Cisplan. Your doctor may recommend a specific diet or suggest foods that may help to reduce side effects. Speak to your doctor or healthcare team about any specific dietary needs.

What should I do if I become pregnant while taking Cisplan?

If you become pregnant while taking Cisplan, it is important to contact your doctor. Cisplan is not recommended during pregnancy and it can be dangerous for the baby if taken during pregnancy.

What if I experience a severe allergic reaction to Cisplan?

If you experience a severe allergic reaction to Cisplan, it is important to seek immediate medical attention.

What other medications should I avoid while taking Cisplan?

You should avoid taking any other medications without first consulting with your doctor. Certain medications can interact with Cisplan and increase your risk of side effects.

Are there any specific foods or beverages I should avoid while taking Cisplan?

It is important to follow your doctor's recommendations when it comes to diet and Cisplan. Eating a healthy balanced diet and avoiding alcohol and cigarettes can help reduce the risk of side effects.

Can I drink alcohol while taking Cisplan?

No, it is not advised to drink alcohol while taking Cisplan. Doing so can increase your risk of serious side effects.

What should I do if I am feeling anxious or depressed while taking Cisplan?

It is normal to feel anxious or depressed while taking Cisplan. Speak to your doctor or healthcare team about your feelings and they can discuss ways to manage them.

Can I take antibiotics while taking Cisplan?

Yes, you can take antibiotics while taking Cisplan, but it is important to let your doctor or healthcare team know so they can ensure there are no drug interactions.

Can I take over-the-counter medications while taking Cisplan?

It is important to check with your doctor before taking any over-the-counter medications while taking Cisplan, as some may interact with the drug and increase your risk of side effects.

Can I drive while taking Cisplan?

It is not advised to drive while taking Cisplan due to the risk of side effects like fatigue, nausea, and dizziness.

Can Cisplan treat advanced cancer?

Cisplan can be used to treat advanced cancer, but its effectiveness can vary depending on the type and stage of cancer being treated.

Can Cisplan be used to treat cancers that have spread to other parts of the body?

Yes, Cisplan can be used to treat cancers that have spread to other parts of the body. However, its effectiveness can vary depending on the type and stage of cancer being treated.

Can Cisplan be used in combination with other chemotherapy drugs?

Yes, Cisplan can be used in combination with other chemotherapy drugs. Your healthcare team will determine the best combination of drugs for you.

How long does it take for Cisplan to take effect?

The length of time it takes for Cisplan to take effect varies depending on the type and stage of cancer being treated. It typically takes a few weeks to see results.

Can Cisplan be used to treat children?

Cisplan can be used to treat certain types of childhood cancer. However, due to its potential for side effects, it is typically only used as a last resort after other treatments have been tried.

Do I need to have regular tests while taking Cisplan?

Yes, it is important to have regular tests while taking Cisplan. Your doctor may order regular blood tests, urine tests, and x-rays to check for side effects and monitor the effectiveness of the treatment.

Is Cisplan covered by insurance?

The cost of Cisplan can vary depending on your insurance provider. It is important to contact your insurance provider to determine what, if any, costs are covered by your plan.

Can I continue working while taking Cisplan?

Depending on the type of job you have, it may be possible to continue working while taking Cisplan. It is important to talk to your doctor or healthcare team about your daily activities before starting Cisplan treatment.

How long does Cisplan stay in the body?

The amount of time Cisplan stays in the body varies depending on the individual. Cisplan can stay in the body for several weeks or months after treatment has been completed.

Can Cisplan cause birth defects?

It is possible for Cisplan to cause birth defects if taken during pregnancy. It is important to speak to your doctor before starting Cisplan treatment if there is a possibility of becoming pregnant in the future.

What should I do if I think I have been exposed to Cisplan?

If you think you have been exposed to Cisplan, it is important to contact your doctor right away. Exposure to Cisplan can be dangerous and it is important to seek medical attention as soon as possible.

Do I need to take a different form of contraception while taking Cisplan?

Yes, it is important to talk to your doctor about contraception while taking Cisplan. Certain forms of birth control can increase your risk of side effects.

Can I get a flu shot while taking Cisplan?

Yes, it is typically safe to get a flu shot while taking Cisplan. However, it is important to speak to your doctor about any additional vaccinations you may need while taking the drug.

Are there any long-term effects of Cisplan?

Yes, there can be long-term effects from Cisplan, such as hearing loss, nerve damage, or an increased risk of infection. It is important to speak to your healthcare team about any long-term effects you may experience.