Catin (ANTIBACTERIALS)

Catin (ANTIBACTERIALS) Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Catin (ANTIBACTERIALS) is a brand name. Its generic name is Trimethoprim.

Introduction

Catin (ANTIBACTERIALS) is a synthetic antimicrobial compound used in combination with sulfamethoxazole (SXT or SMX). It is used in the treatment of a wide variety of infections, including urinary tract infections, acute otitis media, bronchitis, shigellosis, prostatitis, cholera, and pneumonia.

Uses

Catin (ANTIBACTERIALS) is commonly used in combination with Sulfamethoxazole, in the treatment of acute bacterial infections of the urinary tract, such as cystitis, pyelonephritis and acute uncomplicated prostatits. It is also used for shigellosis, chronic bronchitis, acute otitis media, cholera and pneumonia.

Mechanism of Action

Catin (ANTIBACTERIALS) blocks the synthesis of dihydrofolate, an important cofactor in bacterial metabolism, by inhibiting the enzyme dihydrofolate reductase. By doing so, it reduces the production of folic acid in bacteria, and prevents it from using it for DNA production.

How Long Does it Take to Work

Catin (ANTIBACTERIALS) begins to work within 24-72 hours depending on the severity of the infection. It is important to complete full course of treatment as prescribed by your doctor, even when symptoms of the infection disappear.

Absorption

Catin (ANTIBACTERIALS) is rapidly and well absorbed with peak plasma concentrations usually seen in an hour or two after oral administration.

Route of Elimination

Catin (ANTIBACTERIALS) is mainly eliminated unchanged in the urine by glomerular filtration and tubular secretion with only a small amount metabolized.

Dosage

The recommended dosage for adults and children over 12 years is 8-10 mg per kg body weight every twelve hours (maximum 4 g per day). The usual adult dose is one tablet (160 mg) of sulfamethoxazole and one tablet (80 mg) of trimethoprim, twice a day, for 10-14 days. For children under twelve years, the recommended dosage is 5-7 mg/kg body weight every twelve hours, with a maximum daily dose of 60 mg/kg body weight.

Administration

Catin (ANTIBACTERIALS) is available as a tablet or as a suspension in strength of 80 mg/5ml. It should be taken with or after food to enhance absorption. It should not be mixed with antacids containing magnesium or aluminum, as well as products containing iron, zinc, iron, calcium, or sodium bicarbonate, as it will reduce absorption.

Side Effects

The common side effects of trimethoprim include nausea, vomiting, diarrhea, sunburn easily, headache, loss of appetite, and rashes. Other less common side effects can include anemia, thrombocytopenia, leukopenia, and hypersensitivity.

Toxicity

Extensive use of trimethoprim, especially for prolonged periods, can lead to the development of microbial resistance. Large doses of trimethoprim can cause acute renal failure and acute hemolytic anemia. Rarely, it can cause Stevens-Johnson Syndrome and toxic epidermal necrolysis.

Precaution

Catin (ANTIBACTERIALS) should not be used in pregnant women unless absolutely necessary. People with a history of glucose-6-phosphate dehydrogenase deficiency should avoid trimethoprim as it can cause hemolytic anemia. In the case of people with severe hepatic and renal impairment, it is advisable to reduce the dosage.

Interactions

Catin (ANTIBACTERIALS) can interact with certain drugs such as warfarin (causing an increase in prothrombin time), aspirin (increased risk of bleeding), phenytoin (decreases its efficacy by induction of hepatic metabolism) and methotrexate (increase risk of toxicity).

Disease Interaction

People with severe hepatic impairments should avoid using trimethoprim. Furthermore, caution should be taken in people who have depression, diabetes, hematologic disorders, renal impairment, phenylketonuria, seizure disorder, thyroid disorders and Vitamin B12 deficiency.

Drug Interaction

Catin (ANTIBACTERIALS) can interact with drugs such as warfarin, aspirin, phenytoin and methotrexate. It can also interact with other antimicrobials, antacids, penicillins, tetracyclines, antidiabetic drugs, NSAID, theophylline and vitamins.

Food Interactions

Catin (ANTIBACTERIALS) should not be taken with antacids containing magnesium or aluminum, as well as products containing iron, zinc, iron, calcium, or sodium bicarbonate, as it will reduce absorption.

Pregnancy Use

Catin (ANTIBACTERIALS) should not be used in pregnant women unless absolutely necessary. Studies conducted in animals have revealed that trimethoprim has teratogenic effects.

Lactation Use

Catin (ANTIBACTERIALS) is excreted in the breast milk hence it should be avoided in breastfeeding mothers.

Acute Overdose

Symptoms of acute overdose include anorexia, nausea, vomiting, diarrhea, hemolytic anemia, renal failure, and features of hyperkalemia.

Contraindication

Catin (ANTIBACTERIALS) is contraindicated in people with known hypersensitivity to trimethoprim or other sulfonamide derivatives, severe hepatic and renal impairment, folate deficiency and pregnancy.

Use Direction

Catin (ANTIBACTERIALS) should be taken with or after food to enhance absorption. It should not be mixed with antacids containing magnesium or aluminum, as well as products containing iron, zinc, iron, calcium, or sodium bicarbonate, as it will reduce absorption.

Storage Condition

Store trimethoprim tablets at room temperature in an airtight container, away from direct sunlight and away from children and pets.

Volume of Distribution

Catin (ANTIBACTERIALS) has a volume of distribution of ~25 liters.

Half Life

The elimination half life of trimethoprim is ~9-11 hours.

Clearance

Catin (ANTIBACTERIALS) has a renal clearance of ~70 ml/min.

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Some Frequently Asked Questions About Catin (ANTIBACTERIALS)

What is Catin (ANTIBACTERIALS)?

Catin (ANTIBACTERIALS) is an antibiotic medicine used to treat bacterial infections. It works by stopping the growth of bacteria.

What is Catin (ANTIBACTERIALS) used to treat?

Catin (ANTIBACTERIALS) is used to treat a variety of bacterial infections, including bladder infections, sinus infections, bronchitis, and pneumonia.

What are the side effects of Catin (ANTIBACTERIALS)?

The most common side effects of Catin (ANTIBACTERIALS) are nausea, vomiting, diarrhea, rash, headache, and dizziness.

Can Catin (ANTIBACTERIALS) be used during pregnancy?

The safety of Catin (ANTIBACTERIALS) during pregnancy has not been established. It should be used with caution during pregnancy and only if clearly needed.

What should I do if I experience side effects from Catin (ANTIBACTERIALS)?

If you experience side effects from Catin (ANTIBACTERIALS), talk to your doctor or pharmacist for advice. You may need to reduce your dose or stop taking the medicine altogether.

How should I take Catin (ANTIBACTERIALS)?

Take Catin (ANTIBACTERIALS) exactly as prescribed by your doctor. Take it at the same time each day, with or without food. Do not take more or less than directed.

Can I drink alcohol while taking Catin (ANTIBACTERIALS)?

You should not drink alcohol while taking Catin (ANTIBACTERIALS) as it may increase your risk of side effects. Talk to your doctor about the possible risks before consuming alcohol while taking Catin (ANTIBACTERIALS).

Is it safe for children to take Catin (ANTIBACTERIALS)?

Catin (ANTIBACTERIALS) is safe for children to take, however it should only be used when clearly needed. Talk to your doctor before giving Catin (ANTIBACTERIALS) to children.

What should I do if I forget to take my dose of Catin (ANTIBACTERIALS)?

If you forget to take your dose of Catin (ANTIBACTERIALS), take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take your next dose at the regular time.

What should I do if I accidentally take an extra dose of Catin (ANTIBACTERIALS)?

If you take an extra dose of Catin (ANTIBACTERIALS), contact your doctor or pharmacist. You may need to have your blood monitored or receive other medical treatment.

What should I do if I experience severe stomach pain while taking Catin (ANTIBACTERIALS)?

If you experience severe stomach pain while taking Catin (ANTIBACTERIALS), contact your doctor or go to the emergency room immediately. Stomach pain can be a sign of a serious side effect or reaction.

What should I do if I am allergic to Catin (ANTIBACTERIALS)?

If you are allergic to Catin (ANTIBACTERIALS), stop taking the medicine and contact your doctor immediately. You may need to receive medical treatment for your allergic reaction.

Can Catin (ANTIBACTERIALS) be used to treat urinary tract infections?

Yes, Catin (ANTIBACTERIALS) can be used to treat urinary tract infections. It works by killing the bacteria that cause the infection.

What should I do if I experience itching or rash while taking Catin (ANTIBACTERIALS)?

If you experience itching or rash while taking Catin (ANTIBACTERIALS), talk to your doctor for advice. It may be a sign of an allergic reaction or a side effect of the medicine.

Can Catin (ANTIBACTERIALS) cause diarrhea?

Yes, Catin (ANTIBACTERIALS) can cause diarrhea. If you experience diarrhea, talk to your doctor or pharmacist for advice.

Does Catin (ANTIBACTERIALS) affect birth control?

Catin (ANTIBACTERIALS) may decrease the effectiveness of birth control medicines. Talk to your doctor about the use of effective birth control while taking this medicine.

Are there any other medications that I should not take while taking Catin (ANTIBACTERIALS)?

It is important to tell your doctor about all the medications you are taking, including any over the counter medicines that you are taking. Ask your doctor or pharmacist for more information.

Can I take ibuprofen or acetaminophen while taking Catin (ANTIBACTERIALS)?

You can take ibuprofen or acetaminophen while taking Catin (ANTIBACTERIALS). However, it is important to take these medicines at least two hours apart from Catin (ANTIBACTERIALS) to avoid interactions.

Is Catin (ANTIBACTERIALS) available over the counter?

No, Catin (ANTIBACTERIALS) is only available with a prescription. It cannot be purchased over the counter.

Can Catin (ANTIBACTERIALS) be used to treat strep throat?

Yes, Catin (ANTIBACTERIALS) can be used to treat strep throat. However, it cannot be used to treat viral infections.

Can Catin (ANTIBACTERIALS) cause stomach upset?

Yes, Catin (ANTIBACTERIALS) can cause stomach upset. If you experience stomach upset, talk to your doctor or pharmacist for advice.

Can I take Catin (ANTIBACTERIALS) if I am breastfeeding?

You should talk to your doctor before taking Catin (ANTIBACTERIALS) if you are breastfeeding. Catin (ANTIBACTERIALS) can pass into breast milk and may cause side effects in nursing babies.

Does Catin (ANTIBACTERIALS) interact with any other medications?

Yes, Catin (ANTIBACTERIALS) can interact with some other medications. Be sure to tell your doctor about all the medications you are taking, including over the counter medicines.

What should I do if I experience a fever while taking Catin (ANTIBACTERIALS)?

If you experience a fever while taking Catin (ANTIBACTERIALS), contact your doctor immediately. A fever can be a sign of an allergic reaction or a side effect of the medicine.

Is Catin (ANTIBACTERIALS) safe for long term use?

Catin (ANTIBACTERIALS) should only be used for the length of time prescribed by your doctor. Long term use of Catin (ANTIBACTERIALS) can lead to resistance in the bacteria, making the medicine less effective.

Can Catin (ANTIBACTERIALS) cause yeast infections?

Yes, Catin (ANTIBACTERIALS) can cause yeast infections. If you experience frequent yeast infections while taking Catin (ANTIBACTERIALS), talk to your doctor for advice.

Is Catin (ANTIBACTERIALS) more effective than other antibiotics?

Catin (ANTIBACTERIALS) may be more effective than other antibiotics depending on the type of infection being treated. Your doctor will be able to determine the best treatment for your specific infection.

What are the most common side effects of Catin (ANTIBACTERIALS)?

The most common side effects of Catin (ANTIBACTERIALS) are nausea, vomiting, diarrhea, rash, headache, and dizziness.

Can Catin (ANTIBACTERIALS) be taken with milk?

Yes, Catin (ANTIBACTERIALS) can be taken with milk. It may reduce the effectiveness of the medicine if it is taken at the same time as milk or other dairy products.

Can Catin (ANTIBACTERIALS) be used to treat gonorrhea?

Yes, Catin (ANTIBACTERIALS) can be used to treat gonorrhea. It works by killing the bacteria that cause the infection.

Is Catin (ANTIBACTERIALS) safe to take if I have diabetes?

Yes, Catin (ANTIBACTERIALS) is generally safe to take if you have diabetes. However, you should talk to your doctor about your medical history before taking this medicine.

Can Catin (ANTIBACTERIALS) be used for teeth infections?

No, Catin (ANTIBACTERIALS) is not effective in treating teeth infections as it does not penetrate well into the gums. Your dentist may prescribe a different antibiotic to treat a tooth infection.

Can Catin (ANTIBACTERIALS) cause kidney problems?

Yes, Catin (ANTIBACTERIALS) can cause kidney problems. If you experience any signs of kidney problems while taking Catin (ANTIBACTERIALS), contact your doctor immediately.

Can Catin (ANTIBACTERIALS) be used to treat bacterial meningitis?

Yes, Catin (ANTIBACTERIALS) can be used to treat bacterial meningitis. It works by killing the bacteria that cause the infection.

Can I take Catin (ANTIBACTERIALS) if I have high blood pressure?

Yes, Catin (ANTIBACTERIALS) can be used to treat bacterial infections in people with high blood pressure. However, you should talk to your doctor about any other medications you are taking before using Catin (ANTIBACTERIALS).

Can Catin (ANTIBACTERIALS) be used to treat acne?

No, Catin (ANTIBACTERIALS) is not indicated for the treatment of acne. Talk to your doctor about other treatments that may be available to treat your acne.

Can Catin (ANTIBACTERIALS) be used to treat urinary tract infections in cats?

Yes, Catin (ANTIBACTERIALS) can be used to treat urinary tract infections in cats. Your veterinarian will be able to prescribe the appropriate dose for your pet.

Does Catin (ANTIBACTERIALS) affect blood sugar levels?

Yes, Catin (ANTIBACTERIALS) can cause a change in blood sugar levels. It is important to monitor your blood sugar levels closely if you are taking this medicine.

Should I take Catin (ANTIBACTERIALS) with food?

It is not necessary to take Catin (ANTIBACTERIALS) with food, however taking it with a light meal may reduce the risk of stomach discomfort. Talk to your doctor or pharmacist about the best way to take this medicine.