Carbonyl Iron
Carbonyl Iron Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Carbonyl Iron is a brand name. Its generic name is Carbonyl Iron.
Carbonyl Iron
Carbonyl Iron is an organic form of iron, which has been developed for oral supplementation. It is a high purity, easily absorbed form of iron, and has been found to improve iron supplement absorption rates significantly.
Uses For Carbonyl Iron
Carbonyl Iron is used to treat iron deficiency anemia and other conditions that may be caused by an iron deficiency. It can also be used to prevent iron deficiency anemia in certain people, including pregnant women, infants, and elderly individuals. Carbonyl Iron can also be used to treat and/or prevent anemia caused by deficiencies or malabsorption of other nutrients, including vitamin B12, folic acid, and protein.
Mechanism of Action
Carbonyl Iron works by providing an easily absorbed form of iron, which is necessary for the production of red blood cells. Carbonyl iron can be directly absorbed by the intestinal cells, where it can be incorporated into circulating hemoglobin without the help of transferrin or iron-binding proteins. This allows for a more efficient and complete absorption of iron into the bloodstream.
How Long Does it Take to Work?
The effects of Carbonyl Iron can be felt within a few days of beginning treatment. Symptoms of iron deficiency anemia usually begin to improve within a few weeks of beginning treatment. It may take longer for other types of anemia caused by deficiencies of other nutrients.
Absorption
Carbonyl iron is rapidly and completely absorbed from the gut without the need for gastric acid or other iron-binding proteins. This allows for an efficient and complete absorption of iron into the bloodstream, leading to an increase in hemoglobin levels.
Route of Elimination
Carbonyl iron is not metabolized or eliminated. It is stored in the body and eventually excreted in feces.
Dosage and Administration
Carbonyl Iron is typically taken orally in the form of a tablet, capsule, or liquid. Depending on the specific supplement, dosage will vary from person to person and product to product. The recommended daily dose for adults is typically 15 mg per day, and the maximum daily dose for adults is typically 45 mg per day.
Side Effects
Common side effects of Carbonyl Iron include constipation, nausea, and dark stools. Other side effects may include abdominal cramps, vomiting, diarrhea, and dark urine. In rare cases, Carbonyl Iron may cause an allergic reaction.
Toxicity
The acute toxicity of Carbonyl Iron is low. However, long-term excessive intake of Carbonyl Iron may cause toxicity and serious adverse effects, including liver damage and heart failure. Prolonged use of high doses of Carbonyl Iron may increase the risk of iron overload and other health complications.
Precautions
Carbonyl Iron is classified as “Usually Safe” when taken at the recommended dosage, and in healthy individuals. However, it is not recommended for individuals with an iron overload disorder, or those taking other iron supplements or multivitamins. Carbonyl Iron should not be taken by individuals who are pregnant, lactating, or have a history of kidney disease.
Interactions
Carbonyl Iron may interact with certain medications, including antacids, calcium supplements, cholestyramine, and others. It may also interact with certain foods or beverages, including dairy, coffee, and tea. Talk to your healthcare provider about any possible interactions with medications, foods, or beverages.
Disease Interactions
Carbonyl Iron may worsen conditions such as iron overload, renal disease, and/or anemia of chronic disorders. It may also interact with blood disorders, such as thalassemia major, sickle cell anemia, or thrombotic thrombocytopenia purpura. Talk to your healthcare provider about possible interactions if you are being treated for any of the above conditions.
Drug Interactions
Carbonyl Iron may interact with certain medications, including antacids, iron supplements, calcium supplements, cholestyramine, and others. It may also interact with certain other supplements, herbs, and vitamins, such as Vitamin C. Talk to your healthcare provider about possible interactions with these and any other medications or supplements.
Food Interactions
Carbonyl Iron may interact with certain foods, including coffee, tea, and dairy. These foods may interfere with the absorption of iron, and should be avoided or taken with food. Talk to your healthcare provider about potential food interactions.
Pregnancy Use
Carbonyl Iron is approved for use in pregnant and lactating women, as long as the dosage is not excessive. However, talk to your healthcare provider before taking any iron supplements during pregnancy and lactation.
Lactation Use
Carbonyl Iron is approved for use in lactating women, as long as the dosage is not excessive. However, talk to your healthcare provider before taking any iron supplements while breastfeeding.
Acute Overdose
Acute overdose of Carbonyl Iron can lead to signs of iron toxicity, including nausea, lethargy, altered mental status, and organ dysfunction. If you suspect an overdose, contact your healthcare provider immediately.
Contraindications
Carbonyl Iron is contraindicated in individuals with hemochromatosis, hemosiderosis, anemia due to chronic disorders, and renal disease. Carbonyl Iron should also be avoided in individuals taking other iron supplements or multivitamins, as well as in individuals with a history of liver or kidney disease.
Use Directions
Carbonyl Iron should be taken as directed by your healthcare provider. The recommended dose is typically 15 mg per day for adults, not to exceed 45 mg per day. Carbonyl Iron should be taken with food, and accompanied by a full glass of water. It is important to take Carbonyl Iron consistently and regularly, as directed to remain free from iron deficiency.
Storage Condition
Carbonyl Iron should be stored at room temperature, away from moisture, heat, and light. Keep all medications and supplements away from children and pets to avoid accidental overdose.
Volume of Distribution
Carbonyl Iron is well distributed throughout the body but generally accumulates in the liver, muscles, and bone marrow. It is stored in the body until it is eventually excreted in the feces.
Half Life
The half-life of Carbonyl Iron is approximately 4 hours, although it can range from 1 to 8 hours.
Clearance
Carbonyl Iron is cleared from the body primarily through the intestines. It is not metabolized or eliminated by the liver or kidneys.
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