Carbihist
Carbihist Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Carbihist is a brand name. Its generic name is Carbinoxamine.
Carbihist
Carbihist is an antihistamine/anticholinergic medication used to relieve the symptoms of allergies, hay fever, and the common cold. It is part of the ethanolamine class of antihistamines, and works by blocking the binding of histamine to its receptors which results in decreased inflammation and allergy symptoms. Carbihist may be used to reduce swelling, itching, and sneezing associated with allergies and hay fever, and to reduce nasal congestion caused by colds and other conditions.
Uses
Carbihist is used to treat allergies, hay fever, and the common cold. It may also be used to help reduce inflammation and nasal congestion associated with sinusitis. Carbihist is also used to reduce itching from hives and other skin conditions.
Mechanism of Action
Carbihist works by blocking the action of histamine, an allergy-causing chemical that is released by the body in response to allergens. By blocking the histamine receptors, carbinoxamine helps to reduce the allergic reaction in the body. The anticholinergic effects of carbinoxamine also help to reduce inflammation and nasal congestion.
How Long Does it Take to Work?
Carbihist is rapidly absorbed from the gastrointestinal tract and reaches peak blood plasma concentrations within 2-3 hours of administration. The anti-allergic effects of carbinoxamine typically begin within 30 minutes of administration.
Absorption
Carbihist is rapidly absorbed from the gastrointestinal tract and is highly bioavailable.
Route of Elimination
Carbihist is eliminated via renal excretion as well as via metabolism in the liver.
Dosage
Carbihist is available in tablet, syrup, and elixir forms, and is typically taken orally or rectally. Dosage will depend on the condition being treated and should be taken as directed by your doctor. Common adult dosages range from 4mg to 10mg, taken 2-4 times per day. Children and infants may need to take half of the adult dose.
Administration
Carbihist can be taken orally, rectally, or intravenously, depending on the form of the medication. It is typically given 2-4 times daily, with or without food.
Side Effects
Common side effects of carbinoxamine include drowsiness, dizziness, nausea, vomiting, dry mouth, fatigue, blurred vision, and stomach pain.
Toxicity
There is no known toxicity associated with carbinoxamine. However, taking more than the recommended dose may result in an overdose.
Precautions
Carbihist should not be taken if you have narrow angle glaucoma, asthma or other breathing problems, difficulty urinating due to an enlarged prostate, or if you are taking a monoamine oxidase inhibitor (MAOI). Carbihist may also increase the risk of seizures, so it should be used with caution in patients with a history of seizures or other neurological conditions. Be sure to tell your doctor about any allergies or other medical conditions that you have.
Interactions
Carbihist may interact with other medications, including antifungals, antibiotics, antidepressants, allergy medications, high blood pressure medications, muscle relaxants, and other heart or blood pressure medications. Be sure to tell your doctor and pharmacist of all other medications that you are taking.
Disease Interaction
Carbihist may worsen certain medical conditions, such as narrow angle glaucoma, asthma, and difficulty urinating due to an enlarged prostate. It should also be used cautiously in patients with liver or kidney disease, heart disease, seizures, or other neurological conditions.
Drug Interaction
Carbihist may interact with other medications, including antifungals, antibiotics, antidepressants, allergy medications, high blood pressure medications, muscle relaxants, and other heart or blood pressure medications. Be sure to tell your doctor and pharmacist of all other medications that you are taking.
Food Interactions
It is not known if carbinoxamine interacts with food or alcohol, but it is recommended that you consult your doctor or pharmacist for more information.
Pregnancy Use
There is not enough data available to determine the safety of carbinoxamine in pregnant women. It is recommended that you consult your doctor or pharmacist for more information.
Lactation Use
Carbihist may pass into breast milk and should be used cautiously in breast-feeding women. It is recommended that you consult your doctor or pharmacist for more information.
Acute Overdose
An acute overdose of carbinoxamine may result in nausea, vomiting, drowsiness, dizziness, blurred vision, dryness of the mouth, or difficulty breathing. In the event of an overdose, seek medical attention immediately.
Contraindication
Carbihist should not be taken if you have narrow angle glaucoma, asthma or other breathing problems, difficulty urinating due to an enlarged prostate, or if you are taking a monoamine oxidase inhibitor (MAOI).
Use Direction
Carbihist should be taken exactly as prescribed by your doctor. It is typically given 2-4 times daily, with or without food. Do not crush, chew, or break the tablets. Swallow the medication whole and do not take it more often than recommended.
Storage Condition
Carbihist should be stored in room temperature, away from moisture, heat and light. Keep the medication in a secure location where it is inaccessible to children and pets.
Volume of Distribution
The volume of distribution for carbinoxamine is not known.
Half Life
The half life of carbinoxamine is 3-4 hours.
Clearance
The clearance of carbinoxamine is not known.
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