Banocide
Banocide Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Banocide is a brand name. Its generic name is Diethylcarbamazine.
Overview
Banocide (DEC) is an anti-parasitic medication used to treat filarial worm infestations and infections caused by nematodes, mites, or ticks. DEC is also referred to as dithiocarbamate. It is classified as an avermectin/milbemycin. DEC is usually taken orally, although it can also be given topically or by injection. Common side effects associated with DEC include nausea, vomiting, dizziness, and mild headaches.
Uses
DEC is typically used to treat filarial worm infestations, such as those caused by Wuchereria bancrofti and Brugia malayi. It is also used to treat infections caused by nematodes, mites, and ticks.
Mechanism of Action
DEC works by interfering with parasite larvae and adult worm metabolism, causing worms to become paralyzed. This results in its death and eventual destruction of the parasite. It can also help to reduce the damage caused by the worms to infected tissues.
How Long Does It Take To Work?
The exact time it takes for DEC to work in treating filarial worm infestations varies from patient to patient, as well as to the organism being treated. Generally, it can take up to several weeks before symptoms improve.
Absorption
DEC is readily and completely absorbed from the gastrointestinal tract after oral administration. The plasma peak occurs about 45 minutes after administration.
Route of Elimination
DEC is rapidly and extensively metabolized in the liver and the metabolites are excreted in the feces.
Dosage
The dose of DEC depends on the type of parasite being treated and the patient's age, weight, and other factors. Generally, the standard adult dose for filariasis is 200 mg orally, three times daily for 4 days. The standard dose for nematode infections is 200 mg orally, once a day for 21 days.
Administration
DEC can be given orally, topically, or by injection. Oral administration is the most common route of administration.
Side Effects
Common side effects associated with DEC include mild headaches, nausea, vomiting, and dizziness. Rarely, more serious side effects can occur, such as difficulty breathing, rashes and itching, angioneurotic edema, and anaphylaxis.
Toxicity
The toxic dose of DEC is unknown. Symptoms of an overdose may include nausea, vomiting, abdominal pain, dizziness, fatigue, shortness of breath, and confusion.
Precautions and Warnings
DEC should not be used in patients with a history of hypersensitivity to the drug or any of its components. It is also not recommended in patients with hepatic impairment, as it may cause further liver damage. Patients should be closely monitored, and proper precautions should be taken to avoid overdose.
Interactions
DEC can interact with other medications, including antibiotics and antifungal agents. Therefore, it is important to tell your doctor about all medications you are taking, before starting treatment with DEC.
Drug Interaction
DEC may interact with certain medications, including antibiotics and antifungal agents. It is important to tell your doctor about all medications you are taking, before starting treatment with DEC.
Food Interactions
DEC is not known to interact with food or drinks. It is recommended to take it with water or other liquids. Avoid ingesting alcohol while taking DEC.
Pregnancy Use
DEC is not recommended for use during pregnancy, due to the lack of data on its safety and efficacy.
Lactation Use
DEC is not recommended for use during lactation, due to the lack of data on its safety and efficacy.
Acute Overdose
An acute overdose of DEC can cause nausea, vomiting, abdominal pain, dizziness, fatigue, shortness of breath, confusion, and other symptoms. Prompt medical attention should be sought if an overdose is suspected.
Contraindication
DEC should not be used in patients with a history of hypersensitivity to the drug or any of its components. It should also not be used in patients who are pregnant or breastfeeding, as it is not known to be safe or effective.
Use Direction
It is important to follow the instructions provided by your healthcare provider when taking DEC. The dose and duration of therapy depend on the type of infestation or infection being treated and the patient's age, weight, and other factors.
Storage Condition
DEC should be stored in a cool, dry place away from direct sunlight and moisture. Keep this and all medication out of reach of children.
Volume of Distribution
The volume of distribution of DEC in the body is approximately 0.8-1.4 L/kg.
Half Life
The elimination half-life of DEC is approximately 2-4 hours.
Clearance
The clearance of DEC is approximately 25-40 mL/min/kg.
Here you find in details version of Banocide
Some Frequently Asked Questions About Banocide
What is Banocide?
Banocide (DEC) is an orally administered drug that is used to treat filariasis (also known as elephantiasis) caused by infection with threadworm. It is also sometimes used to treat some other parasitic worm infections.
What is the dosage of Banocide?
The recommended dosage of diethylcarbamazine is 6mg/kg of body weight for adults and 10mg/kg for children. For children, the dose may be divided into two parts, with one half taken in the morning and the other half taken in the evening.
What is Banocide used for?
Banocide is used to treat filariasis (also known as elephantiasis) caused by infection with threadworm. It is also sometimes used to treat some other parasitic worm infections.
How does Banocide work?
Banocide works by paralyzing and killing the parasites that cause filariasis. It also blocks the transmission of the infection from one person to another.
How long does it take for Banocide to work?
It typically takes 1-3 days for Banocide to start working. It may take a few weeks or months to see the full effects of the medication.
What are the side effects of Banocide?
Common side effects of Banocide include nausea, vomiting, dizziness, headache, itching, and skin rash. Serious side effects include liver or kidney damage, anemia, and seizures. Call your doctor if you experience any of these symptoms.
Does Banocide interact with any other medications?
Yes, Banocide can interact with other medications, including anticonvulsants, antibiotics, immunosuppressants, and antifungals. Be sure to tell your doctor about all the medications that you are taking before starting Banocide.
Does Banocide cause birth defects?
Banocide is not known to cause birth defects. However, as with any medication, it is important to talk to your doctor before taking Banocide if you are pregnant or planning to become pregnant.
Is Banocide available over the counter?
No, Banocide is not available over the counter and must be prescribed by a doctor.
Can I take Banocide long-term?
Yes, you can take Banocide long-term if it is prescribed by your doctor. However, you should always follow your doctor’s instructions.
How should I store Banocide?
Banocide should be stored at room temperature and away from light and moisture. Do not store the medication in the bathroom. Keep Banocide in a secure place out of the reach of children and pets.
What should I do if I miss a dose of Banocide?
If you miss a dose of Banocide, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed dose.
Can children take Banocide?
Yes, children can take Banocide. The usual dosage is 10mg/kg of body weight. The dose may be divided into two parts, with one half taken in the morning and the other half taken in the evening.
Does Banocide cause liver damage?
Yes, Banocide can cause liver damage. It is important to monitor your liver function while taking this medication and to call your doctor immediately if you experience any symptoms of liver damage, such as yellowing of the skin or eyes, dark urine, abdominal pain, or tiredness.
Can I drink alcohol with Banocide?
No, you should not drink alcohol while taking Banocide. Drinking alcohol can increase your risk of experiencing side effects from the medication, such as stomach irritation, nausea, dizziness, and drowsiness.
Will Banocide cure my infection?
It depends on the type of infection you have. Banocide is used to treat filariasis (also known as elephantiasis) caused by infection with threadworm. It is also sometimes used to treat some other parasitic worm infections. Be sure to talk to your doctor to find out if it is the right medication for your infection.
What if I am allergic to Banocide?
If you are allergic to Banocide, you should not take it. Instead, talk to your doctor about other treatment options that might be more suitable for you. Some people experience serious allergic reactions to Banocide, so it is important to tell your doctor if you have had an allergic reaction to this medication in the past.
Is Banocide safe for pregnant women?
It is not recommended that pregnant women take Banocide. There is insufficient data available about the safety of this medication during pregnancy, so be sure to talk with your doctor before taking it.
What should I do if I experience side effects while taking Banocide?
If you experience any side effects while taking Banocide, you should talk to your doctor immediately. Serious side effects include liver or kidney damage, anemia, and seizures.
Can I drive while taking Banocide?
You should not drive while taking Banocide, since the medication can cause drowsiness and dizziness. It is best to avoid any potentially hazardous activities such as driving while taking this medication.
Can I take Banocide with other medications?
Yes, you can take Diethylcarb