Avas Ez
Avas Ez Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Avas Ez is a brand name. Its generic name is Ezetimibe + Atorvastatin.
Introduction
Avas Ez is a combination drug containing ezetimibe and atorvastatin, used in the treatment of high cholesterol and hyperlipidemia.Uses For
Avas Ez is indicated for the treatment of primary hyperlipidemia and mixed/atherogenic dyslipidemia, including homozygous familial hypercholesterolemia and in patients with hypercholesterolemia at high risk for coronary heart disease and in combination with other lipid-lowering therapies e.g. bile acid sequestrants.Mechanism Of Action
Avas Ez works by reducing the absorption of cholesterol in the intestine by inhibiting an intestinal absorption protein, and in combination with atorvastatin, by inhibiting the production of cholesterol by the liver.How Long Does it Take to Work?
Avas Ez may take 4 to 6 weeks to reach maximum effect.Absorption
Ezetimibe is rapidly and almost completely absorbed from the gastrointestinal tract, and it has bioavailability of approximately 60%. Atorvastatin is rapidly and extensively absorbed from the gastro-intestinal tract after oral administration.Route of Elimination
Ezetimibe is eliminated primarily by Biliary Excretion, and atorvastatin is eliminated by the liver via CYP3A4 and by biliary excretion.Dosage
The recommended starting dose is 10 mg or 20 mg of Ezetimibe + 10 to 20 mg of Atorvastatin, once daily, taken in the evening. The recommended dose is 10mg + 40mg daily, but doses up to 10 mg + 80mg may be used.Administration
Avas Ez is taken orally once daily with or without food, usually in the evening.Side Effect
Common side effects associated with Avas Ez use include headache, abdominal pain, nausea, vomiting, diarrhea, constipation, dizziness, muscle pain and weakness, and joint pain.Toxicity
Avas Ez is considered to be safe when used according to the recommended dose. There is no known overdose toxicity, but overdose may be associated with increased risk of side effects.Precautions
Avas Ez should not be used in patients who are pregnant, lactating, or with liver dysfunction. It should not be taken by patients who are allergic to ezetimibe or atorvastatin, or by patients with known hypersensitivity to any of the components in the product.Interaction
Avas Ez may interact with certain vitamin supplements and other medications. Tell your doctor or pharmacist if you are taking any other medications, including over-the-counter products and herbal supplements.Disease Interaction
Avas Ez may increase risk for serious muscle and liver injury. Patients with pre-existing liver disease should be monitored closely.Drug Interaction
Avas Ez may interact with a variety of drugs, including anticoagulant, anticonvlulsant, antiplatelet, anti-arrhythmic, and antihypertensive drugs, as well as fibrates, warfarin, HIV protease inhibitors, antibiotics, or calcium channel blockers.Food Interaction
Avas Ez should not be taken with high fat/high cholesterol meals as this may decrease the absorption of the medication.Pregnancy Use
Avas Ez should not be used during pregnancy as the safety and efficacy has not been established.Lactation Use
Avas Ez should not be used during lactation as the safety and efficacy of the drug has not been established.Acute Overdose
Avas Ez may cause serious side effects if taken in an overdose. Symptoms of overdose include muscle weakness, nausea, vomiting, and diarrhea.Contraindication
Avas Ez is contraindicated in patients with hypersensitivity to any of the ingredients of this medication, in individuals with severe hepatic impairment, and in pregnant women.Use Direction
Avas Ez should be taken exactly as prescribed by the healthcare provider. Do not take more or less medication than prescribed.Storage Condition
Avas Ez should be stored at room temperature away form light and moisture. Do not expose to excess heat or cold.Volume of Distribution
Avas Ez has a systemic distribution of approximately 1000 L.Half Life
The elimination half life of Avas Ez is approximately 22 hours.Clearance
Avas Ez is cleared mainly through the liver via a series of metabolic pathways.Here you find in details version of Avas Ez
Some Frequently Asked Questions About Avas Ez
What is the generic name of Ezetimibe+Atorvastatin?
The generic name of Ezetimibe+Atorvastatin is Ezetimibe/Atorvastatin.
What is Ezetimibe+Atorvastatin used for?
Ezetimibe+Atorvastatin is used to lower cholesterol levels in adults. It can also help prevent heart-related conditions such as heart attack, stroke, and coronary heart disease.
What are the benefits of taking Ezetimibe+Atorvastatin?
Ezetimibe+Atorvastatin can help lower bad (LDL) cholesterol levels and increase good (HDL) cholesterol levels to help reduce the risk of heart-related conditions like heart attack, stroke, and coronary heart disease.
How do I take Ezetimibe+Atorvastatin?
Ezetimibe+Atorvastatin is taken once daily, with or without food. Follow your doctor's instructions carefully when taking any medication.
Are there any side effects of taking Ezetimibe+Atorvastatin?
As with any medication, side effects can occur. Some of the most common side effects are headache, fatigue, abdominal pain, and nausea. If you experience any of these symptoms, or any other unusual symptoms, call your doctor immediately.
What should I do if I miss a dose of Ezetimibe+Atorvastatin?
If you miss a dose, take it as soon as you remember. If it's close to the time to take your next dose, skip the missed dose and take the next dose as usual. Do not take two doses at once.
Can I take Ezetimibe+Atorvastatin with other medications?
Always talk to your doctor about other medications you are taking before starting Ezetimibe+Atorvastatin. Certain medications may interact with Ezetimibe+Atorvastatin, increasing or decreasing its effectiveness, or potentially causing serious side effects.
What is the recommended dosage of Ezetimibe+Atorvastatin?
The recommended starting dose of Ezetimibe+Atorvastatin is 10 mg/10 mg once daily. Your doctor may adjust your dose based on your cholesterol levels.
How long can I take Ezetimibe+Atorvastatin?
You should take Ezetimibe+Atorvastatin as long as recommended by your doctor. The average treatment course is 12 weeks but may be longer depending on your response to the medication.
What should I do if I experience an allergic reaction to Ezetimibe+Atorvastatin?
If you experience an allergic reaction while taking Ezetimibe+Atorvastatin, stop taking it immediately and contact your doctor. Serious side effects such as difficulty breathing, itching, hives, swelling, and dizziness may indicate an allergic reaction.
Does Ezetimibe+Atorvastatin cause weight gain?
Weight gain is a possible side effect of Ezetimibe+Atorvastatin. If you experience any unusual weight gain while taking this medication, speak to your doctor.
Can I drink alcohol while taking Ezetimibe+Atorvastatin?
It is not recommended to drink alcohol while taking Ezetimibe+Atorvastatin, as it may increase your risk of side effects. Speak to your doctor about drinking alcohol while taking Ezetimibe+Atorvastatin.
What should I do if I experience dizziness or fatigue while taking Ezetimibe+Atorvastatin?
If you experience dizziness or fatigue while taking Ezetimibe+Atorvastatin, you should let your doctor know immediately. These may be signs of an adverse reaction to the medication.
Are there any dietary restrictions when taking Ezetimibe+Atorvastatin?
You should follow a healthy diet when taking Ezetimibe+Atorvastatin. Reduce intake of saturated fats, trans fats, cholesterol, and sodium, and increase your intake of fruits, vegetables, and fiber.
How does Ezetimibe+Atorvastatin work to lower cholesterol levels?
Ezetimibe works by inhibiting the absorption of cholesterol in the intestines. Atorvastatin works by blocking the enzymes in the liver responsible for producing cholesterol.
Can I take Ezetimibe+Atorvastatin while pregnant or breastfeeding?
It is not recommended to take Ezetimibe+Atorvastatin while pregnant or breastfeeding. Speak to your doctor before taking this medication if you are pregnant or breastfeeding.
Does Ezetimibe+Atorvastatin interact with other medications?
Ezetimibe+Atorvastatin can interact with some medications, so always check with your doctor or pharmacist before taking any new medications while taking Ezetimibe+Atorvastatin.
What foods should I avoid when taking Ezetimibe+Atorvastatin?
You should avoid foods high in saturated and trans fat and cholesterol. Additionally, avoiding foods high in sodium can help reduce your risk of side effects. Speak to your doctor or dietician for more information.
How long will it take to see the effects of Ezetimibe+Atorvastatin?
You should start to see improved cholesterol levels within 8 to 12 weeks of taking Ezetimibe+Atorvastatin. Always follow your doctor's instructions for the length of your treatment course.
Can I take Ezetimibe+Atorvastatin if I have liver or kidney disease?
It is not recommended to take Ezetimibe+Atorvastatin if you have liver or kidney disease. Speak to your doctor before taking this medication if you have any existing medical conditions.
Does Ezetimibe+Atorvastatin have any drug interactions?
Ezetimibe+Atorvastatin can interact with certain medications, increasing or decreasing their effectiveness. Speak to your doctor or pharmacist before taking any medications while taking Ezetimibe+Atorvastatin.
Does Ezetimibe+Atorvastatin help to prevent heart attacks and strokes?
Yes, Ezetimibe+Atorvastatin can help to reduce the risk of heart attacks and strokes by lowering cholesterol levels. However, this medication should not be taken to prevent these conditions. Speak to your doctor for more information.
Are there any natural alternatives to Ezetimibe+Atorvastatin?
Yes, there are several natural alternatives to Ezetimibe+Atorvastatin. Speak to your doctor or dietician for more information on some lifestyle modifications and natural supplements that may help to lower your cholesterol levels.
Is Ezetimibe+Atorvastatin covered by insurance?
It depends on your insurance plan. Check with your insurance carrier to determine if Ezetimibe+Atorvastatin is covered. Your pharmacist may also be able to provide information.
How often do I need to have my cholesterol levels checked while taking Ezetimibe+Atorvastatin?
Your doctor may recommend that you have your cholesterol levels checked at regular intervals while taking Ezetimibe+Atorvastatin. It is important to monitor your cholesterol levels so that the medication dose can be adjusted, if necessary.
What should I do if I experience muscle pain or weakness while taking Ezetimibe+Atorvastatin?
If you experience muscle pain or weakness while taking Ezetimibe+Atorvastatin, stop taking it immediately and contact your doctor. These could be signs of a serious side effect known as rhabdomyolysis.
Am I able to donate blood while taking Ezetimibe+Atorvastatin?
No, you should not donate blood while taking Ezetimibe+Atorvastatin. Speak to your doctor before donating blood while taking this medication.
Can I get a generic version of Ezetimibe+Atorvastatin?
Yes, a generic version of Ezetimibe+Atorvastatin is available. Speak to your doctor or pharmacist about the availability of generic versions of the medication.
Are there any other cholesterol-lowering medications that I can take if I can’t take Ezetimibe+Atorvastatin?
Yes, there are other cholesterol-lowering medications available. Speak to your doctor about other medications that may be more suitable for you.
Can I just take Atorvastatin instead of Ezetimibe+Atorvastatin?
No, it is not recommended to take Atorvastatin instead of Ezetimibe+Atorvastatin. Speak to your doctor if you would like to change medications.
Will Ezetimibe+Atorvastatin interact with my other medications?
Yes, Ezetimibe+Atorvastatin may interact with other medications. Always speak to your doctor or pharmacist before taking any medication while taking Ezetimibe+Atorvastatin.
What should I do if I overdose on Ezetimibe+Atorvastatin?
If you think you have overdosed on Ezetimibe+Atorvastatin, contact your local poison control center or emergency room immediately. Symptoms of overdose may include nausea, vomiting, dizziness, and abdominal pain.
What precautions should I take when taking Ezetimibe+Atorvastatin?
Before taking Ezetimibe+Atorvastatin, inform your doctor of any allergies you have and any other medications you are taking. Additionally, it is important to follow a healthy, balanced diet and to get regular exercise while taking this medication.