Aquatears
Aquatears Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Aquatears is a brand name. Its generic name is Dextran + Hypromellose.
Introduction
Dextran and Hypromellose are two viscous polysaccharide derivatives, which are commonly used as gelling agents and lubricants in a range of pharmaceutical products, including ophthalmic solutions, suspensions, emulsions, and topical creams.Uses
Dextran and Hypromellose are used as a protective colloid for stabilizing emulsions, suspensions and dispersions and often prescribed for ophthalmic use, as well as for intestinal and urinary tract laxation.Mechanism of Action
Dextran and Hypromellose are both hydrophilic molecules that bind to water, allowing for the formation of suspensions and emulsions. This helps protect other drugs in the product from damage due to environmental factors like humidity and temperature. They also act as lubricants, creating a slippery coating on the skin or eye surface which prevents irritation and tearing.How Long Does it Take to Work?
The effects of Dextran and Hypromellose can be seen immediately after administration.Absorption
Due to their hydrophilic nature, Dextran and Hypromellose molecules are not easily absorbed into the body, so very little, if any, is taken up.Route of Elimination
Dextran and Hypromellose are eliminated via the feces and the urine.Dosage
Dosage information should be provided by a doctor.Administration
Dextran and Hypromellose may be administered orally, intravenously, or rectally depending on the specific product and patient requirement.Side Effects
Dextran and Hypromellose are generally considered to be safe, but some side effects may be experienced including itching, rash, stomach discomfort, bloating, diarrhea, or constipation.Toxicity
Dextran and Hypromellose are low-toxicity materials, and no adverse systemic effects have been noted with recommended doses.Precaution
Dextran and Hypromellose should be used with caution in individuals with a known hypersensitivity or allergy to either material.Interaction
Dextran and Hypromellose may interact with other drugs in the body. It is best to consult a doctor or pharmacist before taking any medications.Disease Interaction
Dextran and Hypromellose may interact with diseases such as diabetes and heart failure, and should be taken with caution in patients with these conditions.Drug Interaction
Dextran and Hypromellose may interact with some drugs, including anticoagulants, blood thinners, and laxatives. It is best to consult a doctor or pharmacist before taking any medications.Food Interactions
Dextran and Hypromellose may interact with certain foods, particularly those that are high in fiber or starch. It is best to consult a doctor or pharmacist before making any dietary changes.Pregnancy Use
Dextran and Hypromellose should be avoided during pregnancy.Lactation Use
Dextran and Hypromellose should be avoided during breastfeeding.Acute Overdose
An overdose of Dextran and Hypromellose may cause symptoms such as abdominal discomfort, diarrhea, or nausea and vomiting. In case of an overdose, it is recommended to consult a doctor or pharmacist immediately.Contraindication
Dextran and Hypromellose should not be used in individuals with known hypersensitivity to either of the materials.Use Direction
Dextran and Hypromellose should be used in accordance with the instructions provided by the doctor or pharmacist.Storage Condition
Dextran and Hypromellose should be stored at room temperature and away from light and moisture.Volume of Distribution
The volume of distribution of Dextran and Hypromellose is unknown.Half Life
The half-life of Dextran and Hypromellose in the body is unknown.Clearance
The clearance rate of Dextran and Hypromellose is also unknown.Here you find in details version of Aquatears
Some Frequently Asked Questions About Aquatears
What is Dextran?
Dextran is a polysaccharide produced by certain bacteria from glucose molecules. It is usually a linear chain of a few hundred to several thousand glucose molecules and is used as a stabilizer, thickener, and emulsifier for a number of consumer products and pharmaceuticals.
What is Hypromellose?
Hypromellose is a semisynthetic, inert, viscoelastic polymer used as an ophthalmic lubricant, as well as an excipient and controlled-release vehicle in oral and topical pharmaceutical formulations.
What is Aquatears?
Aquatears is a combination product of polysaccharide Polydextran and semisynthetic semi-inert hypromellose polymer. It is used as an ophthalmic lubricant, as an excipient and controlled-release vehicle in oral and topical pharmaceutical formulations.
What are the benefits of using Aquatears?
The combined product provides better functionality than either polysaccharide or hypromellose alone. It improves stability, thickening properties, and adhesion to the surface of the ocular tissue. Furthermore, Aquatears facilitates better drug release and absorption, and improves the overall performance of drug formulations compared to Dextran and Hypromellose individually.
How is Aquatears administered?
Aquatears is typically administered topically, drop by drop, applied directly to the affected area.
Is Aquatears safe for use?
Yes, Aquatears is considered safe for use and has been approved by the US FDA for ophthalmic lubrication and other purposes.
What are the possible side effects of Aquatears?
The possible side effects are mild and include irritation, inflammation, oedema, and blurred vision. Other rare but possible side effects include anaphylactic reactions.
How long does Aquatears take to work?
It typically takes about 15 to 20 minutes for Aquatears to take effect.
What are the contraindications for using Aquatears?
Aquatears is contraindicated in patients with known hypersensitivity to any component of the formulation.
What is the recommended dosage of Aquatears?
The dose of Aquatears should be determined by the physician based on the patient’s condition and response to treatment.
Can Aquatears be used in combination with other medication?
Yes, Aquatears can be used in combination with other medications, but any such combination should be discussed with the healthcare provider.
How long does a bottle of Aquatears last?
The shelf life of Aquatears is up to two years and it should be stored at room temperature.
Can Aquatears be stored in the refrigerator?
No, Aquatears should not be stored in the refrigerator and should be stored at room temperature.
What is the shelf life of Aquatears?
The shelf life of Aquatears is up to two years.
What are the storage requirements for Aquatears?
Aquatears should be stored at room temperature, away from direct sunlight and in an airtight container.
What are the inactive ingredients in Aquatears?
The inactive ingredients in Aquatears include polysorbate 80, sodium chloride, potassium chloride, glycerin, sodium bicarbonate and preservatives.
Can Aquatears be used during pregnancy?
Yes, Aquatears can be used during pregnancy but only if a physician recommends it.
Can Aquatears be used on children?
Yes, Aquatears can be used in children over 2 years of age, but it should be used with caution and only if recommended by a physician.
Should Aquatears be used in the presence of an allergic reaction?
No, Aquatears should not be used in the presence of an allergic reaction.
Can Aquatears cause an allergic reaction?
Yes, Aquatears can cause an allergic reaction, and it should be used with caution and only if recommended by a physician.
Can Aquatears be used for the treatment of dry eyes?
Yes, Aquatears can be used for the treatment of dry eyes, but only if recommended by a physician.
What is the onset time of Aquatears?
The onset time of Aquatears is typically 15 to 20 minutes.
What is the difference between Aquatears and other ophthalmic lubricants?
Aquatears is a combination product whereas other ophthalmic lubricants are typically either Polydextran or Hypromellose alone. The combined product offers better lubrication properties than either polysaccharide or hypromellose alone.
How long can Aquatears be used before needing a new prescription?
The duration of use of Aquatears can vary depending on the severity of the condition and the patient’s response to treatment, and it should be discussed with the healthcare provider.
Does Aquatears expire?
Yes, Aquatears has an expiration date printed on the packaging and should not be used beyond this date.
Does Aquatears come in different strengths?
No, Aquatears comes in one strength.
What are the most common adverse reactions associated with Aquatears?
The most common adverse reactions associated with Aquatears are irritation, inflammation, oedema, and blurred vision. These side effects are typically mild in nature.
Can Aquatears be used with contact lenses?
Yes, Aquatears can be used with contact lenses but it should be used as directed by the physician.
Is Aquatears safe for use in patients with diabetes?
Yes, Aquatears is safe for use in patients with diabetes, but any changes in blood sugar levels should be monitored carefully.
Does Aquatears have any drug interactions?
Yes, Aquatears may interact with other medications, and any such interactions should be discussed with the healthcare provider.
Can Aquatears cause blurred vision?
Yes, Aquatears may cause blurred vision, but this is usually mild in nature and should improve with continued use of the product.
Can Aquatears cause a rash?
Yes, Aquatears may cause a mild rash, but this is usually mild in nature and should improve with continued use of the product.
Is Aquatears available over the counter?
No, Aquatears is a prescription-only medication and it should be used only if recommended by a healthcare provider.
How much does Aquatears cost?
The cost of Aquatears varies depending on the pharmacy and the strength of the product.
Can Aquatears be used while breastfeeding?
Yes, Aquatears can be used while breastfeeding but only if recommended by a physician.
Can Aquatears be used with other medications?
Yes, Aquatears can be used with other medications, but any such combination should be discussed with the healthcare provider.
Are there any age restrictions for using Aquatears?
Yes, Aquatears should not be used in children under the age of 2 years and should be used with caution in children under 12 years of age.
Are there any drug interactions associated with Aquatears?
Yes, Aquatears may interact with other medications, and any such interactions should be discussed with the healthcare provider.
What are the benefits of using Aquatears?
The benefits of Aquatears include improved stability, thickening properties, and adhesion to the surface of the ocular tissue. Furthermore, it facilitates better drug release and absorption, and improves the overall performance of drug formulations compared to using Dextran and Hypromellose individually.
Can Aquatears be used for long term treatment?
Yes, Aquatears can be used for long term treatment but any such use should only be done under the supervision of a healthcare provider.
Does Aquatears need to be taken on an empty stomach?
No, Aquatears does not need to be taken on an empty stomach.
Does Aquatears require special handling?
No, Aquatears does not require special handling and can be stored at room temperature.
What type of packaging is available for Aquatears?
Aquatears is available in single-use vials, eye dropper bottles, and plastic dispensers.