Aprinox
Aprinox Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Aprinox is a brand name. Its generic name is Bendroflumethiazide.
Aprinox
Aprinox is an oral diuretic commonly prescribed to treat high blood pressure (hypertension) and edema (fluid retention). It is used alone or in combination with other drugs to treat a variety of medical conditions. It works by reducing the amount of salt and fluids in the body, which can help lower your blood pressure and reduce swelling.
Uses For
Aprinox is used to treat high blood pressure (hypertension). It is often used in combination with other drugs, such as beta blockers or ACE inhibitors, to treat more severe cases of hypertension. It is also used to treat edema (fluid retention) caused by conditions such as congestive heart failure or kidney failure. It can also be used to reduce calcium levels in patients with kidney stones or hypercalcemia (high calcium in the blood).
Mechanism of Action
Aprinox works by decreasing the amount of salt and fluids in the body, resulting in the removal of water and electrolytes (such as sodium and potassium) in the urine. By decreasing the amount of salt and fluids in the body, it can help lower blood pressure and reduce swelling.
How Long Does it Take to Work?
Aprinox usually takes effect within 1-3 hours after taking the medication. It may take 1-2 weeks for the full effects of the medication to be seen.
Absorption
Aprinox is completely absorbed from the GI tract. The time to peak effect is 1-3 hours.
Route of Elimination
Aprinox is eliminated through the kidneys.
Dosage
The dosage of bendroflumethiazide varies depending on the condition being treated and the patient’s response to the medication. Typical doses range from 1.25-10 mg per day. It is typically taken once or twice daily with food.
Administration
Aprinox is an oral medication that is taken by mouth with or without food. Take this medication as directed by your doctor. Do not take more or less than the prescribed amount. Follow all directions on the prescription label.
Side Effect
Common side effects of bendroflumethiazide include dizziness, weakness, headache, drowsiness, nausea, vomiting, loss of appetite, dry mouth, abdominal pain, increased urination, diarrhea, and rash. If these effects are bothersome or do not go away, contact your doctor. Serious side effects of bendroflumethiazide include low blood pressure, electrolyte imbalances, dehydration, and changes in blood sugar levels.
Toxicity
Aprinox overdose can be serious and potentially life-threatening. Symptoms of an overdose include dizziness, confusion, blurred vision, weakness, fainting, rapid or slow heartbeat, feeling lightheaded, and nausea. Seek immediate medical attention if you think you have overdosed on bendroflumethiazide.
Precaution
Aprinox can interfere with the absorption of other drugs and can decrease the effectiveness of other medications. Tell your doctor about all medications you are taking, including over-the-counter medications, vitamins, and herbal supplements. Do not drive or operate heavy machinery until you know how bendroflumethiazide affects you. Avoid drinking alcohol while taking bendroflumethiazide, as it can increase the risk of side effects.
Interaction
Aprinox can interact with other medications, including other diuretics, blood pressure medications, heart medications, nonsteroidal anti-inflammatory drugs (NSAIDs), and oral diabetes medications. Tell your doctor about any medications you are taking before starting treatment with bendroflumethiazide.
Disease Interaction
Aprinox may exacerbate conditions such as diabetes mellitus, renal impairment, gout, and systemic lupus erythematosus. Tell your doctor about any medical conditions you have before starting treatment with bendroflumethiazide.
Drug Interaction
Aprinox can interact with certain drugs, including diuretics, calcium channel blockers, corticosteroids, and nonsteroidal anti-inflammatory drugs (NSAIDs). Tell your doctor about any medications you are taking before starting treatment with bendroflumethiazide.
Food Interactions
Aprinox should be taken with food or a glass of milk to reduce the risk of stomach upset. Avoid drinking alcohol while taking bendroflumethiazide, as it can increase the risk of side effects.
Pregnancy Use
Aprinox use is not recommended during pregnancy, as it can cause harm to the developing fetus or newborn. Discuss the risks and benefits of using Aprinox during pregnancy with your doctor.
Lactation Use
There is not enough information to determine the safety of Aprinox during lactation. Discuss the risks and benefits of using Aprinox during lactation with your doctor.
Acute Overdose
An overdose of bendroflumethiazide can be serious and may lead to life-threatening symptoms. Symptoms of an overdose include dizziness, confusion, blurred vision, weakness, fainting, rapid or slow heartbeat, feeling lightheaded, and nausea. Seek immediate medical attention if you think you have overdosed on bendroflumethiazide.
Contraindication
Aprinox is contraindicated in patients with an allergy or hypersensitivity to the drug, kidney disease, severe heart failure, high potassium levels, and certain types of diabetes. Tell your doctor about any medical conditions you have before starting treatment with bendroflumethiazide.
Use Direction
Take bendroflumethiazide as directed by your doctor with or without food. Do not take more than the prescribed amount of bendroflumethiazide, as this can lead to serious side effects.
Storage Condition
Store bendroflumethiazide at room temperature away from direct light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Volume of Distribution
The volume of distribution of bendroflumethiazide is 150-250 L.
Half Life
The half-life of bendroflumethiazide is 1-3 hours.
Clearance
The clearance of bendroflumethiazide is 20-30 ml/min.
Here you find in details version of Aprinox