Amantadine

Amantadine Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Amantadine is a brand name. Its generic name is Amantadine.

Amantadine

Amantadine is a medication used to treat Parkinson's disease, post-influenza syndromes, drug-induced extrapyramidal symptoms, and complications associated with acute viral respiratory illness. It is also sometimes used as an adjunct treatment for certain types of influenza A.

Uses

Amantadine is used to treat Parkinson's disease and complications associated with flu. It may also be used in combination with other medications to treat Parkinson's disease and may be used to treat people who have recently had the flu.

Mechanism of Action

Amantadine works by increasing dopamine levels in the brain and inhibiting reuptake of the neurotransmitter. This increases the available dopamine for nerve transmission, making it a useful therapy for treatment of Parkinson’s symptoms and other movement disorders.

How Long Does It Take to Work?

The effects of amantadine can be felt within a few hours of taking the medication, with peak effects occurring within 2-3 days. It can take up to two weeks for the full effects to be seen.

Absorption

Amantadine is absorbed quickly and completely, with peak concentrations of the drug in the bloodstream occurring within 1 to 2 hours. It is also rapidly distributed throughout the body.

Route of Elimination

Amantadine is eliminated primarily through the kidneys, with about 80% of the drug being excreted unchanged in the urine. Small amounts of the drug are also excreted through the bile.

Dosage

Amantadine is available in tablets or capsules in the following dosages: 8 mg, 10 mg, 12.5 mg, 15 mg, 20 mg, 25 mg, 30 mg, and 40 mg. The recommended starting dose for Parkinson's disease is 5 mg three times a day, increasing up to 15 mg three times a day depending on response. For influenza, the recommended dose is 100 mg twice daily.

Administration

Amantadine can be taken with or without food. It should be taken with a full glass of water. Swallow the whole tablet or capsule whole, do not crush, chew, divide, or dissolve it before swallowing.

Side Effects

Common side effects of amantadine include nausea, loss of appetite, constipation, dizziness, nervousness or irritability, and insomnia. It can also cause blurred vision, dry mouth, weight loss, and confusion.

Toxicity

Amantadine is generally safe and well tolerated. However, overdose of this medication can lead to serious health complications. Symptoms of an overdose include nausea, vomiting, loss of appetite, tremor, confusion, hallucinations, and coma.

Precaution

It is important to use caution when taking amantadine. This medication can interact with other medications and may cause serious side effects when taken with certain drugs. Patients should inform their healthcare provider of any medications they are taking, and any medical conditions they may have.

Interaction

Amantadine can interact with certain medications such as anticholinergics, narcotics, and tricyclic antidepressants. It can also interact with kidneys, liver disease, and heart disease. Patients should speak with their doctor about possible interactions.

Disease Interaction

Patients with certain medical conditions should use caution when taking amantadine. Patients with glaucoma, seizures, urinary tract obstruction, narrow angle glaucoma, difficulty urinating, irregular heartbeat, and high blood pressure should not take this medication.

Drug Interaction

Amantadine can interact with many other medications and should not be taken with certain drugs, such as antacids, MAO inhibitors, anti-seizure medications, or certain antibiotics. Patients should tell their doctor about all medications they are taking.

Food Interactions

Patients should not take amantadine with alcohol, as this can increase the risk of side effects. Patients should avoid eating high-fat or greasy foods while taking this medication, as it may reduce the effectiveness of the drug.

Pregnancy Use

Amantadine should be used with caution during pregnancy, as it can cause birth defects in the fetus. Women who are pregnant or are planning to become pregnant should discuss the risks and benefits of taking this medication with their doctor.

Lactation Use

Use of amantadine during breastfeeding is not recommended, as it is excreted into breast milk and may cause harm to the baby. Women who are breastfeeding should discuss the risks and benefits of taking this medication with their doctor.

Acute Overdose

In the event of an overdose, it is important to seek immediate medical attention. Symptoms of an overdose can include nausea, vomiting, confusion, hallucinations, and coma.

Contraindication

Amantadine is contraindicated in patients with certain medical conditions, such as glaucoma, seizures, urinary tract obstruction, narrow angle glaucoma, difficulty urinating, irregular heartbeat, and high blood pressure.

Use Direction

Amantadine should be taken as directed by your doctor. Do not take more or less of the medication than prescribed. Do not crush, chew, divide, or dissolve the tablets before swallowing. Take this medication with a full glass of water.

Storage Condition

Amantadine should be stored at room temperature in a dry place. Keep the medication away from children and pets. Do not keep outdated medications or medications no longer needed.

Volume of Distribution

The volume of distribution of amantadine is about 10 liters per kilogram. This means that the drug is distributed throughout the body.

Half Life

The half-life of amantadine is about 30 hours. This means that after 30 hours, the concentration of the medication in the blood is reduced by half.

Clearance

Amantadine is eliminated primarily through the kidneys. About 80% of the medication is excreted unchanged in the urine. Small amounts are also excreted through the bile.

Here you find in details version of Amantadine

Some Frequently Asked Questions About Amantadine

What is Amantadine?

Amantadine is a medication used to treat certain viral infections, as well as to reduce symptoms or prevent the occurrence of certain neurological conditions.

What is Amantadine used for?

Amantadine is used to treat certain viral infections, such as influenza A, as well as to reduce symptoms or prevent the occurrence of Parkinson's disease and other certain neurological conditions.

How does Amantadine work?

Amantadine works by inhibiting the function of an enzyme involved in the replication of certain types of viruses, thus preventing them from multiplying and causing infection.

What conditions is Amantadine used to treat?

Amantadine is used to treat certain viral infections, such as influenza A, and to reduce symptoms or prevent the occurrence of Parkinson's disease and other certain neurological conditions.

Is Amantadine safe to take?

Amantadine is generally safe to take if taken as directed by a doctor or pharmacist. Some people, however, may experience certain side effects, so it is important to discuss any potential risks with a doctor before taking this medication.

What are the side effects of Amantadine?

The most common side effects associated with Amantadine include nausea, vomiting, headaches, dizziness, drowsiness, and trouble sleeping. Other rare but serious side effects include confusion, hallucinations, and depression. It is important to discuss any potential side effects with a doctor before taking this medication.

Who should not take Amantadine?

Amantadine is not recommended for people with an allergy to any of the ingredients in the medication, people with certain kidney or heart conditions, pregnant women, or people taking certain medications, such as anticoagulants or immunosuppressants. It is important to discuss any potential risks with a doctor before taking this medication.

Is Amantadine a controlled substance?

No, Amantadine is not a controlled substance.

How often should I take Amantadine?

The frequency and dosage of your Amantadine treatment depend on the condition being treated and other factors, such as age and weight. It is important to follow the instructions provided on the prescription label or by your doctor.

Is Amantadine a narcotic?

No, Amantadine is not a narcotic.

What happens if I miss a dose of Amantadine?

If you miss a dose of Amantadine, it is important to take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue on your regular dosing schedule. Do not take a double dose to make up for a missed dose.

Can Amantadine be taken with other medications?

It is important to inform your doctor about all medications you are taking, including vitamins and supplements, before starting Amantadine. Some medications may interact with Amantadine, so it is important to make sure your doctor is aware of any other medications you are taking.

Is Amantadine an antiviral?

Yes, Amantadine is an antiviral used to treat certain viral infections, such as influenza A.

Can Amantadine be used for long-term treatment?

The length of your Amantadine treatment depends on the condition being treated and other factors, such as age and weight. It is important to follow the instructions provided on the prescription label or by your doctor.

What should I do if I experience side effects from Amantadine?

If you experience any side effects from Amantadine, it is important to inform your doctor. It is also important to discuss any potential risks associated with taking this medication.

What is the recommended dosage for Amantadine?

The recommended dosage for Amantadine depends on the condition being treated and other factors, such as age and weight. It is important to follow the instructions provided on the prescription label or by your doctor.

What are the possible interactions of Amantadine?

Some medications may interact with Amantadine, so it is important to inform your doctor about all medications you are taking, including vitamins and supplements, before starting Amantadine.

What is the generic name for Amantadine?

The generic name for Amantadine is memantine.

What if I take too much Amantadine?

If you think you have taken too much Amantadine, it is important to seek medical attention immediately. Symptoms of an overdose may include tremors, dizziness, confusion, tachycardia, and seizures.

Can Amantadine be used during pregnancy?

Amantadine is not recommended for pregnant women, as there is a potential risk of birth defects or other problems. It is important to discuss any potential risks with a doctor before taking this medication.

Can Amantadine be used during breastfeeding?

Amantadine is not recommended for women who are breastfeeding, as there is a potential risk of affecting the nursing infant. It is important to discuss any potential risks with a doctor before taking this medication.

Is Amantadine addictive?

No, Amantadine is not considered addictive.

What is the cost of Amantadine?

The cost of Amantadine varies depending on the dosage form, strength, and quantity prescribed. It is important to speak with your doctor or pharmacist for more information.

How long does it take for Amantadine to start working?

The time it takes for Amantadine to start working depends on the condition being treated and other factors. It is important to follow the instructions provided on the prescription label or by your doctor.

Can I buy Amantadine over the counter?

No, Amantadine is only available by prescription.

How should Amantadine be stored?

Amantadine should be stored at room temperature, away from moisture and heat. It is important to keep this medication out of the reach of children and pets.

What is the best way to take Amantadine?

The best way to take Amantadine is as instructed by your doctor. It is important to follow the instructions provided on the prescription label or by your doctor.

What are the most common brand names for Amantadine?

The most common brand names for Amantadine are Symmetrel, Respodan, Amantrel, and Mantadan.

What is the usual dose of Amantadine?

The usual dose of Amantadine depends on the condition being treated and other factors, such as age and weight. It is important to follow the instructions provided on the prescription label or by your doctor.

Can Amantadine be used in combination with other medications?

It is important to inform your doctor about all medications you are taking, including vitamins and supplements, before starting Amantadine. Some medications may interact with Amantadine, so it is important to make sure your doctor is aware of any other medications you are taking.

When should I take Amantadine?

The timing of your Amantadine treatment depends on the condition being treated and other factors, such as age and weight. It is important to follow the instructions provided on the prescription label or by your doctor.

How long does Amantadine remain in the body?

The amount of time Amantadine remains in the body depends on the dosage and frequency of administration and other factors. It is important to follow the instructions provided on the prescription label or by your doctor.

What is the difference between Amantadine and memantine?

Amantadine and memantine are both medications used to reduce symptoms or prevent the occurrence of certain neurological conditions. Amantadine is also used to treat certain viral infections, such as influenza A. Memantine is the generic name for Amantadine.

Can I drink alcohol while taking Amantadine?

It is not recommended to drink alcohol while taking Amantadine, as it could increase the risk of side effects. It is important to discuss any potential risks with a doctor before taking this medication.

Does Amantadine cause weight gain?

Yes, some people may experience weight gain while taking Amantadine. It is important to discuss any potential risks with a doctor before taking this medication.

What should I avoid while taking Amantadine?

It is important to avoid driving or operating any heavy machinery while taking Amantadine, as it can cause drowsiness or confusion. Additionally, it is important to avoid drinking alcohol while taking Amantadine, as it could increase the risk of side effects.

Can Amantadine be used to treat hives?

No, Amantadine is not used to treat hives.

Can Amantadine be used to treat a cold or flu?

Yes, Amantadine is used to treat certain viral infections, such as influenza A.

Can Amantadine be used to treat bacterial infections?

No, Amantadine is not used to treat bacterial infections. It is used to treat certain viral infections, such as influenza A.

Can Amantadine be used to treat depression?

No, Amantadine is not used to treat depression. It is used to treat certain viral infections, as well as to reduce symptoms or prevent the occurrence of Parkinson's disease and other certain neurological conditions.

Can Amantadine be used to treat asthma?

No, Amantadine is not used to treat asthma. It is used to treat certain viral infections, as well as to reduce symptoms or prevent the occurrence of Parkinson's disease and other certain neurological conditions.

Can Amantadine be used to treat allergies?

No, Amantadine is not used to treat allergies. It is used to treat certain viral infections, as well as to reduce symptoms or prevent the occurrence of Parkinson's disease and other certain neurological conditions.

Can Amantadine be used to treat migraines?

No, Amantadine is not used to treat migraines. It is used to treat certain viral infections, as well as to reduce symptoms or prevent the occurrence of Parkinson's disease and other certain neurological conditions.

Can Amantadine be used to treat anxiety?

No, Amantadine is not used to treat anxiety. It is used to treat certain viral infections, as well as to reduce symptoms or prevent the occurrence of Parkinson's disease and other certain neurological conditions.

Is Amantadine used to treat memory loss?

Yes, Amantadine is used to reduce symptoms or prevent the occurrence of certain neurological conditions, such as memory loss.