Alfogel

Alfogel Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Alfogel is a brand name. Its generic name is Aluminium phosphate.

Aluminium Phosphate Introduction

Alfogel is an inorganic salt that is made of aluminium and phosphate molecules. It is used in a variety of industries for different purposes. In the pharmaceutical industry, aluminium phosphate is used for a variety of applications including adjuvant therapy (the use of an agent to enhance the ability of a drug to produce an effect), as a mild antacid, as an active ingredient in certain medications, and as a bonding agent in tablet and capsule formulations.

Uses For Aluminium Phosphate

Alfogel is used for a variety of therapeutic purposes. It is commonly used as an antacid or as an adjuvant therapy to enhance the action of certain medications, such as anti-inflammatory and anti-bacterial drugs. In addition, it serves as an active ingredient in several medications, including antidiarrheal and antifungal preparations. Alfogel is also used in the manufacturing of tablets and capsules, as it binds together various ingredients to form one solid product.

Mechanism Of Action

Alfogel works by forming an insoluble complex with hydroxide, bicarbonate, and other anions (dissolved molecules with a negative charge). This inhibits the release of gas from the stomach, which reduces the unpleasant sensation known as heartburn. Additionally, the formation of an insoluble phosphate complex can also reduce the acidity of the contents in the stomach, helping to relieve acid reflux.

How Long Does It Take To Work?

Alfogel begins working in the digestive tract within a few minutes of ingestion. The maximum effect is usually felt between 30 minutes and 60 minutes after ingestion, depending on the individual and the strength of the medication taken.

Absorption

Alfogel is not readily absorbed in the human body. It is mostly excreted from the urine and faeces unaltered.

Route Of Elimination

Alfogel is eliminated primarily through the kidneys. After being absorbed by the intestines, it is rapidly eliminated in the urine.

Dosage

The recommended dosage for aluminium phosphate depends on the preparation. Generally, adults should take 1-2 tablets three times a day with meals and at bedtime. However, it is important to check with a doctor or pharmacist for the specific dosage and to make sure it is appropriate for the individual's case.

Administration

Alfogel tablets should be taken orally with a full glass of water. They should be swallowed whole and should not be crushed or chewed.

Side Effect

The most common side effects associated with aluminium phosphate include abdominal discomfort, nausea, diarrhea, constipation, and decreased appetite. Rare side effects include headache, tinnitus (ringing in the ears), and vertigo (sensation of spinning).

Toxicity

Alfogel is generally well tolerated when taken as directed. However, high doses can lead to aluminium toxicity, which can cause a range of symptoms, including muscle weakness, confusion, memory loss, and fatigue.

Precaution

Alfogel should not be taken by people who have kidney or liver disease, who are pregnant or breastfeeding, and who are taking certain medications, such as cyclosporine. In addition, it should be used with caution in people who have diarrhea, as aluminium phosphate can worsen the condition.

Interaction

Alfogel can interact with several medications, including antacids containing magnesium, such as Mylanta and Maalox; anticonvulsants, such as Valproic acid and Phenobarbital; and certain antibiotics, such as erythromycin and ciprofloxacin.

Disease Interaction

Alfogel may worsen symptoms of certain diseases, such as kidney and liver disease, as well as diarrhea, and should be used with caution in people with such conditions.

Drug Interaction

As mentioned, aluminium phosphate can interact with certain medications, including antacids containing magnesium, such as Mylanta and Maalox; anticonvulsants, such as Valproic acid and Phenobarbital; and certain antibiotics, such as erythromycin and ciprofloxacin.

Food Interactions

Alfogel should not be taken with dairy products, as it can reduce the effectiveness of the medication. Additionally, it should not be taken with iron supplements.

Pregnancy Use

Alfogel should be used with caution in pregnant women, as it may damage the developing fetus. It should only be used when clearly needed and under a doctor's supervision.

Lactation Use

Alfogel is classified as a Pregnancy Category C drug, meaning its effects on a nursing baby are not known. Therefore, it should only be used with caution in breast-feeding women, under doctor's supervision.

Acute Overdose

Signs of an acute (sudden) overdose of aluminium phosphate include vomiting, diarrhea, fatigue, and abdominal discomfort. In the case of an overdose, a doctor should be contacted immediately.

Contraindication

Alfogel is contraindicated in people who have known allergies to aluminium, those with kidney or liver disease, pregnant or breastfeeding women, and people taking certain medications, such as cyclosporine.

Use Direction

Alfogel tablets should be taken orally with a full glass of water. They should be swallowed whole and should not be crushed or chewed. Adults should take 1-2 tablets three times a day with meals and at bedtime.

Storage Condition

Alfogel should be stored at room temperature, away from direct heat and light. Keep the tablets in their original packaging until use.

Volume of Distribution

The volume of distribution for aluminium phosphate is not well-established.

Half Life

The half-life of aluminium phosphate is not known.

Clearance

Alfogel is cleared from the body primarily through the kidneys.

Here you find in details version of Alfogel

Some Frequently Asked Questions About Alfogel