Aflapin
Aflapin Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Aflapin is a brand name. Its generic name is Aflapin.
Aflapin Introduction
Aflapin is a brand manufacturer containing the active ingredients overdose and diclofenac in the form of a transdermal patch. This medication is used to temporarily relieve minor joint pain, muscle pain and stiffness. It is an analgesic and anti-inflammatory non-steroidal anti-inflammatory drug (NSAID).
Uses for
Aflapin is used to provide temporarily relief from minor joint pain, muscle pain, and stiffness. It is also used as a male contraceptive.
Mechanism of Action
Aflapin works by blocking the action of cyclooxygenase, an enzyme responsible for converting arachidonic acid to prostaglandins. It prevents the formation of substances that cause pain, inflammation and fever in the body.
How Long Does It Take to Work?
Aflapin typically starts its action within an hour of application and provides relief from pain and inflammation for up to 12 hours.
Absorption
Aflapin is formulated for transdermal absorption and is slowly absorped through the skin over the course of a day. The peak plasma concentration is achieved after 5-7 hours of application.
Route of Elimination
Aflapin is primarily metabolized in the liver and is excreted through the urine.
Dosage
Aflapin should be administered as a transdermal patch. The recommended dose for adults is one patch applied once a day. The patch should be applied to a clean and dry area of the skin and changed every 24 hours. It should not be applied to the same place twice.
Administration
Aflapin is typically administered as a transdermal patch and applied directly to clean, dry skin. The patch should be applied for 24 hours and can be worn during activities such as showering or swimming.
Side Effects
Common side effects of Aflapin include nausea, headache, dizziness, drowsiness, stomach pain, vomiting, diarrhea, constipation, and rash.
Toxicity
Aflapin is generally well tolerated at recommended doses and is generally not considered to be toxic in humans. However, an overdose of Aflapin may be fatal.
Precaution
It is important to follow the instructions carefully when using Aflapin. Avoid using it for longer than recommended and contact your doctor immediately if you experience any severe side effects.
Interaction
Before taking Aflapin, tell your doctor about any other medications you are currently taking, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements.
Disease Interaction
Aflapin should not be used by patients who have a history of heart, liver, or kidney disease. As well it should not be used by patients who are pregnant or breastfeeding. It may also interact with certain medications, so always speak to a doctor before taking Aflapin.
Drug Interaction
Aflapin may interact with some other medications, including antihypertensive drugs, anticoagulants, and other NSAIDs. It may also interact with certain herbal supplements. Always talk to your doctor before taking Aflapin.
Food Interactions
Aflapin may interact with certain foods or beverages, including alcohol. Always talk to your doctor before taking Aflapin.
Pregnancy Use
Aflapin should not be used during pregnancy. The safety of Aflapin during pregnancy has not been established.
Lactation Use
Aflapin should be used with caution in women who are breastfeeding since it may pass into the mother’s milk and harm the baby. Always speak to a doctor before taking Aflapin.
Acute Overdose
An overdose of Aflapin is dangerous and possibly life-threatening. If you believe you or someone else have taken an overdose of Aflapin, seek emergency medical attention immediately.
Contraindication
Aflapin should not be used by patients with a history of heart, liver, or kidney disease. It should also not be used by patients who are pregnant or breastfeeding.
Use Direction
Aflapin is administered as a transdermal patch. Apply the patch directly to clean, dry skin and replace it every 24 hours. Do not use the same spot twice. Avoid applying additional pressure on the patch and do not cut or tear it.
Storage Condition
Aflapin should be stored at room temperature away from direct light, moisture, and heat. Do not keep near the reach of children.
Volume of Distribution
Aflapin has a volume of distribution of 0.36 L/kg.
Half Life
The half-life of Aflapin is 4-7 hours.
Clearance
The clearance of Aflapin is 49.6 L/h.
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