Acivir

Acivir Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? Acivir is a brand name. Its generic name is Aciclovir.

Acivir Introduction

Acivir, also known as Acyclovir, is an antiviral medication used to treat a variety of herpes-related infections, such as shingles, genital herpes, and chickenpox. It is an oral medication available in both tablet and oral suspension form. It is also available in topical cream form.

Uses for Acivir

Acivir is used to treat and prevent infections such as herpes simplex virus (HSV)1 and 2, chickenpox, and shingles. It is used to reduce pain and heal sores caused by these infections. It can also help to prevent the spread of the infections.

Mechanism of Action

Acivir works by stopping the virus from making more copies of itself. It does this by stopping the activity of an enzyme the virus needs to replicate. This stops the virus from spreading, and ultimately helps it to clear up.

How Long Does It Take to Work?

Acivir may take up to 2 days for the viral shedding to reduce. It is important to note that the virus can still be passed on during this time. For the best results, Acivir should be taken for the full course of treatment, which can be up to 5 days.

Absorption

Acivir is rapidly and almost completely absorbed from the gastrointestinal tract. It is approximately 20% bio available, which means it should be taken with food or milk to enhance its absorption.

Route of Elimination

Acivir is eliminated via the kidneys, primarily as unchanged (or active) drug. Approximately 20–30% will be eliminated in the urine as inactive metabolites.

Dosage

Dosage of Acivir will depend on the type of infection being treated. The usual adult dosage for herpes simplex virus infections is 200-400 mg by mouth 5 times daily, up to five days. For genital herpes, the dosage is 200mg every 4 hours (6 doses per day), up to five days. For shingles, the dosage is 800mg five times per day for 7-10 days.

Administration

Acivir can be taken with or without food. It is important to take it regularly and exactly as your doctor prescribes. Do not stop taking it, even if you feel better, unless your doctor tells you to.

Side Effect

Common side effects of Acivir include nausea, stomach pain, headache, dizziness, and feeling tired. Some patients may experience an allergic reaction such as hives or difficulty breathing, which should be reported to their healthcare provider immediately.

Toxicity

Acivir has a low risk of toxicity when taken as directed and following your healthcare provider's instructions. The most common adverse reactions are gastrointestinal disturbances such nausea, vomiting, and diarrhea.

Precautions

Patients with kidney or liver disease should use Acivir with caution. Acivir should not be taken during pregnancy, unless prescribed by a healthcare provider. Before taking Acivir, it's important to let your healthcare provider know if you have any allergies, sensitivities, or other health conditions.

Interactions

Acivir may interact with other medications such as probenecid, tubocurarine, certain antibiotics, and some antacids. It's important to tell your healthcare provider if you are taking other medications or supplements.

Disease Interaction

Patients with a compromised immune system, such as those with HIV, and those with kidney or liver disease, should use Acivir with caution as it can cause more serious side effects. It is also important for these patients to follow their healthcare provider’s instructions.

Drug Interactions

Acivir may interact with medications such as probenecid, tubocurarine, certain antibiotics, and some antacids. Tell your doctor if you are taking any other medications or supplements.

Food Interactions

Acivir should be taken with food or milk to enhance its absorption. Its effectiveness can also be decreased if taken with certain foods.

Pregnancy Use

Acivir should not be taken during pregnancy, unless prescribed by a healthcare provider. It can pass into breast milk, so it should not be taken by breastfeeding mothers.

Lactation Use

Acivir should not be used by breastfeeding mothers. It can pass into breast milk and can harm a nursing baby.

Acute Overdose

An overdose of Acivir may lead to severe and even life-threatening side effects. It is important to contact your healthcare provider or local poison control center as soon as possible if you think you may have taken too much Acivir.

Contraindication

Acivir is contraindicated in patients who are allergic or hypersensitive to it. It is also contraindicated in patients with renal impairment or severe hepatic impairment.

Use Direction

It is important to follow the instructions of your healthcare provider when taking Acivir. Do not take more or less medication than prescribed or discontinue taking the medication abruptly without consulting your healthcare provider.

Storage Condition

Store Acivir tablets at room temperature away from moisture and heat. Keep the suspension form in the fridge (but not in the freezer).

Volume of Distribution

The volume of distribution is 0.2-1L/kg for Acivir.

Half Life

The average half life is 2.0 to 4.7 hours for Acivir.

Clearance

The average clearance of Acivir is 0.1 L/hr/kg.

Here you find in details version of Acivir

Some Frequently Asked Questions About Acivir

What is Acivir?

Acivir is an antiviral drug used to treat infections caused by certain types of viruses. It is most commonly used to treat ‘cold sores’ (herpes simplex) and ‘genital herpes’ (genital herpes infections).

What are the uses of Acivir?

Acivir is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chicken pox.

What form does Acivir come in?

Acivir is available as a tablet, an oral suspension, and a topical cream.

How does Acivir work?

Acivir works by stopping the virus from multiplying and spreading, and so helps to reduce the severity and duration of the infection. However, it does not cure the infection.

How should Acivir be taken?

Acivir should be taken as directed on the label, or as prescribed by your doctor. It is usually taken with food. The dosage and length of treatment will depend on the type and severity of infection.

Who should not take Acivir?

Acivir should not be taken by people who are allergic to it or any of its ingredients, and by pregnant or breastfeeding women.

What are the side effects of Acivir?

Side effects of Acivir include nausea, vomiting, diarrhea, headache, rash, and dizziness.

Can Acivir be taken with other medications?

Acivir may interact with other medications, such as warfarin and probenecid, so it is important to tell your doctor about all medications you are taking.

What should be done in case of an overdose?

If an overdose of Acivir is suspected, contact a poison control center or emergency room immediately.

What should I do if I miss a dose?

If you miss a dose of Acivir, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

How long should I take Acivir?

The length of treatment with Acivir will depend on the type and severity of the infection. Follow all instructions given to you by your doctor.

Can I buy Acivir over-the-counter?

No, Acivir is available only with a doctor’s prescription.

What is the most common brand name for Acivir?

The most common brand name for Acivir is Zovirax.

Does Acivir cause drowsiness?

Yes, Acivir may cause drowsiness. It is important to use caution when operating heavy machinery or driving while taking Acivir.

How long does it take for Acivir to start working?

Acivir usually starts to work within a few days, but it can take up to a week or more for symptoms to resolve.

Can Acivir be used to treat infections other than those caused by herpes viruses?

No, Acivir is not effective against infections caused by other types of viruses.

What is the recommended dosage of Acivir?

The recommended dosage of Acivir will vary depending on the type and severity of the infection. Follow all instructions on the label or as prescribed by your doctor.

Can Acivir be used in children?

Yes, Acivir can be used in children over the age of two. Children younger than two years should not take Acivir.

Is Acivir safe for pregnant or breastfeeding women?

No, Acivir should not be taken by pregnant or breastfeeding women, as it can harm the baby.

How long does Acivir stay in the body?

The half-life of Acivir is around 2-4 hours, meaning it is generally out of the body within a day or two.

What are the storage instructions for Acivir?

Acivir should be stored at room temperature, away from heat and moisture. Keep out of reach of children.

Should Acivir be taken with food?

It is recommended to take Acivir with food.

Can Acivir be used to prevent infections?

In some cases, Acivir can be used to prevent infections. Consult your doctor for more information.

Can Acivir be used to treat shingles?

Yes, Acivir is an effective treatment for shingles. It is important to start treatment as soon as possible.

What should I do if I experience any allergic reactions while taking Acivir?

If you experience any allergic reactions while taking Acivir, discontinue use and contact your doctor immediately.

Can Acivir cause weight gain?

No, Acivir does not cause weight gain.

Is Acivir an antibiotic?

No, Acivir is an antiviral drug, not an antibiotic.

Can Acivir be used during an outbreak?

Yes, Acivir can be used to treat a herpes outbreak.

Can Acivir be used to treat cold sores?

Yes, Acivir is an effective treatment for cold sores.

What are the side effects of Acivir in children?

The most common side effects of Acivir in children are nausea, vomiting, diarrhea, headache, rash, and dizziness.

How soon after taking Acivir should I expect to see improvement?

You may see some improvement in symptoms within a few days of starting Acivir, but it can take up to a week or more for full symptom relief.

What should I do if I experience any other side effects while taking Acivir?

If you experience any other side effects while taking Acivir, contact your doctor immediately.

Are there any interactions between Acivir and alcohol?

Yes, alcohol can interact with Acivir and should be avoided while taking the medication.

Can I take Acivir with other medicines?

It is important to tell your doctor about all medications you are taking, including over-the-counter medications and dietary supplements, as Acivir can interact with some medications. Your doctor will advise you on any potential interactions.

Are there any long-term side effects associated with using Acivir?

No, there are no known long-term side effects associated with Acivir.

Does Acivir have any effect on the effectiveness of birth control?

No, Acivir does not have any effect on the effectiveness of birth control.

What is the recommended dose of Acivir in children?

The recommended dose of Acivir in children will depend on the child's body weight and the type and severity of the infection. Consult your doctor for specific dosage and dosing interval recommendations.

What are the possible side effects of Acivir in infants?

The most common side effects of Acivir in infants are nausea, vomiting, diarrhea, headache, rash, and dizziness.

Can Acivir be used for long-term treatment?

In some cases, Acivir may be used for long-term treatment. Consult your doctor for specific recommendations.

Can Acivir be used to treat chickenpox?

Yes, Acivir can be used to treat chickenpox in children over the age of two.

Is Acivir safe to take with other medicines?

Yes, Acivir is generally safe to take with other medications, but you should always tell your doctor about all medications you are taking as some interactions may occur.

Does Acivir cause any upset stomach?

Yes, Acivir may cause mild stomach upset, such as nausea, vomiting, and diarrhea.

Can Acivir be used to treat genital herpes?

Yes, Acivir is an effective treatment for genital herpes.

Does Acivir interact with any other drugs?

Yes, Acivir can interact with other medications. It is important to tell your doctor about all medications you are taking as some interactions may occur.

Can Acivir be taken with other vitamins or supplements?

It is important to tell your doctor about all vitamins, herbal supplements, and medications you are taking, as some may interact with Acivir.