A-Meb Tablet 135 mg
A-Meb Tablet 135 mg Uses, Dosage, Side Effects, Mechanism of Action, How Long Does it Take to Work? A-Meb Tablet 135 mg is a brand name. Its generic name is Mebeverine Hydrochloride.
A-Meb Tablet 135 mg
A-Meb Tablet 135 mg is a powerful antispasmodic agent belonging to the antimuscarinic group of drugs. It acts directly on the smooth muscle of the gut wall to relax it and reduce spasms in the intestinal tract. It is effective in relieving symptoms of irritable bowel syndrome (IBS) such as stomach pain, cramps, bloating, constipation, and diarrhea.
Uses For
A-Meb Tablet 135 mg is indicated for the relief of abdominal pain and cramps associated with irritable bowel syndrome (IBS) and other abdominal disorders such as colitis and Crohn's disease.
Mechanism of Action
A-Meb Tablet 135 mg works by blocking the action of acetylcholine, a chemical messenger which transmits signals to the muscles in the intestine. By blocking this action, the muscles relax, resulting in relief from pain and other symptoms associated with IBS.
How Long Does it Take to Work?
A-Meb Tablet 135 mg generally takes between 24 to 48 hours to take complete effect, depending on the individual.
Absorption
A-Meb Tablet 135 mg is rapidly absorbed from the digestive tract, with peak levels reached within 1-3 hours.
Route of Elimination
A-Meb Tablet 135 mg is eliminated mainly through the feces, with only a small amount being excreted in the urine.
Dosage
A-Meb Tablet 135 mg is available in tablets for oral administration containing 135 mg of the active ingredient. It is typically taken up to three times a day, with or without food. The maximum recommended daily dose is 405 mg.
Administration
A-Meb Tablet 135 mg tablets should be swallowed whole with plenty of water. They should not be crushed or chewed as this can reduce the absorption of the medication.
Side Effects
The most common side effects of A-Meb Tablet 135 mg are dry mouth, blurred vision, nausea, vomiting, abdominal pain, constipation, and headache.
Toxicity
A-Meb Tablet 135 mg is generally well tolerated and is not expected to be toxic at recommended doses.
Precautions
A-Meb Tablet 135 mg can interact with other medications and may not be suitable for people with certain medical conditions such as renal or hepatic impairment. It should also be used with caution in people with glaucoma and those who are pregnant or breastfeeding.
Interaction
A-Meb Tablet 135 mg can interact with other medications, particularly those which affect the nervous system such as anticholinergics, antidepressants, antihistamines, and antispasmodics. It should not be used concurrently with other anticholinergic medications.
Disease Interaction
A-Meb Tablet 135 mg can interact with certain medical conditions such as heart disease, glaucoma, urinary tract blockage or difficulty urinating, enlarged prostate, and narrow-angle glaucoma.
Drug Interaction
A-Meb Tablet 135 mg may interact with other medications and is not recommended for concurrent use with anticholinergics, antidepressants, antihistamines, and antispasmodics.
Food Interactions
A-Meb Tablet 135 mg may interact with certain foods and alcohol, so it is important to check with your doctor before taking this medication if you are on a special diet or if you drink alcohol.
Pregnancy Use
A-Meb Tablet 135 mg is not recommended for use during pregnancy, and it is not known whether it is safe to use during pregnancy. It should be avoided during the first trimester.
Lactation Use
A-Meb Tablet 135 mg is not recommended for use during breastfeeding, and it is not known whether it is safe to use during breastfeeding. It should be avoided during the first trimester.
Acute Overdose
The symptoms of an acute overdose of A-Meb Tablet 135 mg include dry mouth, blurred vision, nausea, vomiting, abdominal cramps, constipation, and drowsiness. In severe cases, an anticholinergic crisis may occur, and medical attention should be sought immediately.
Contraindication
A-Meb Tablet 135 mg is contraindicated in patients with known hypersensitivity to the drug or any of its components. It should also be used with caution in patients with hepatic impairment or glaucoma.
Use Directions
A-Meb Tablet 135 mg should be taken as directed by your doctor, typically up to three times a day with or without food. It should be swallowed whole and should not be crushed or chewed. The maximum recommended daily dose is 405 mg.
Storage Condition
A-Meb Tablet 135 mg should be stored at room temperature (15-30°C) in a well-closed container, away from moisture and sunlight.
Volume of Distribution
A-Meb Tablet 135 mg has a volume of distribution of approximately 4 L/kg.
Half Life
A-Meb Tablet 135 mg has a half-life of approximately 2-3 hours.
Clearance
A-Meb Tablet 135 mg has a clearance of approximately 0.2 L/h/kg.
Here you find in details version of A-Meb Tablet 135 mg